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- EBC-46 abstract "EBC-46 is a experimental drug candidate being studied pre-clinically by the Australian company Ecobiotics (specifically its drug discovery subsidiary Qbiotics). It was discovered through an automated screening process of natural products by selecting increasingly purified fractions of plant extracts, based on their ability to produce the desired activity profile. This is then followed by artificial synthesis of the isolated compound to confirm its chemical structure. EBC-46 is a phorbol ester which, along with other related compounds, acts as a protein kinase C regulator.The initial lead came from observation that marsupials found the seed of Fontainea picrosperma unpalatable due to an inflammatory chemical present in reasonably high concentrations. This was identified as 12-tigloyl-13-(2-methylbutanoyl)-6,7-epoxy-4,5,9,12,13,20-hexahydroxy-1-tiglian-3-one.ECB-46 is an extract from the blushwood berries of Queensland, Australia.".
- EBC-46 pubchem "23627739".
- EBC-46 thumbnail EBC-46.svg?width=300.
- EBC-46 wikiPageID "28166609".
- EBC-46 wikiPageLength "3375".
- EBC-46 wikiPageOutDegree "12".
- EBC-46 wikiPageRevisionID "697794425".
- EBC-46 wikiPageWikiLink Category:Diterpenes.
- EBC-46 wikiPageWikiLink Category:Experimental_cancer_drugs.
- EBC-46 wikiPageWikiLink Ester.
- EBC-46 wikiPageWikiLink Fontainea_picrosperma.
- EBC-46 wikiPageWikiLink Hylandia.
- EBC-46 wikiPageWikiLink Ingenol_mebutate.
- EBC-46 wikiPageWikiLink Marsupial.
- EBC-46 wikiPageWikiLink Natural_product.
- EBC-46 wikiPageWikiLink Phorbol.
- EBC-46 wikiPageWikiLink Pre-clinical_development.
- EBC-46 wikiPageWikiLink Protein_kinase_C.
- EBC-46 wikiPageWikiLink Thapsigargin.
- EBC-46 wikiPageWikiLinkText "EBC-46".
- EBC-46 c "30".
- EBC-46 h "42".
- EBC-46 molecularWeight "562.647".
- EBC-46 o "10".
- EBC-46 pubchem "23627739".
- EBC-46 routesOfAdministration "injected".
- EBC-46 smiles "O=C1CCC4CCC2CC2C4C5OC35CO".
- EBC-46 verifiedrevid "451562722".
- EBC-46 wikiPageUsesTemplate Template:Cascite.
- EBC-46 wikiPageUsesTemplate Template:Citation_needed.
- EBC-46 wikiPageUsesTemplate Template:Drugbankcite.
- EBC-46 wikiPageUsesTemplate Template:Drugbox.
- EBC-46 wikiPageUsesTemplate Template:Medref.
- EBC-46 wikiPageUsesTemplate Template:Reflist.
- EBC-46 subject Category:Diterpenes.
- EBC-46 subject Category:Experimental_cancer_drugs.
- EBC-46 hypernym Candidate.
- EBC-46 type ChemicalSubstance.
- EBC-46 type Drug.
- EBC-46 type Person.
- EBC-46 type Chemical.
- EBC-46 type Diterpene.
- EBC-46 type Drug.
- EBC-46 type Terpene.
- EBC-46 type ChemicalObject.
- EBC-46 type Thing.
- EBC-46 type Q8386.
- EBC-46 comment "EBC-46 is a experimental drug candidate being studied pre-clinically by the Australian company Ecobiotics (specifically its drug discovery subsidiary Qbiotics). It was discovered through an automated screening process of natural products by selecting increasingly purified fractions of plant extracts, based on their ability to produce the desired activity profile. This is then followed by artificial synthesis of the isolated compound to confirm its chemical structure.".
- EBC-46 label "EBC-46".
- EBC-46 sameAs Q5322564.
- EBC-46 sameAs EBC-46.
- EBC-46 sameAs m.0cmb6ws.
- EBC-46 sameAs EBC-46.
- EBC-46 sameAs EBC-46.
- EBC-46 sameAs Q5322564.
- EBC-46 wasDerivedFrom EBC-46?oldid=697794425.
- EBC-46 depiction EBC-46.svg.
- EBC-46 isPrimaryTopicOf EBC-46.