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- Drug_repositioning abstract "Drug repositioning (also known as drug repurposing, re-profiling, re-tasking or therapeutic switching) is the application of known drugs and compounds to new indications (i.e., new diseases).A significant advantage of drug repositioning over traditional drug development is that since the repositioned drug has already passed a significant number of toxicity and other tests, its safety is known and the risk of failure for reasons of adverse toxicology are reduced. More than 90% of drugs fail during development, and this is the most significant reason for the high costs of pharmaceutical R&D. In addition, repurposed drugs can bypass much of the early cost and time needed to bring a drug to market. On the other hand drug repositioning faces some challenges itself since the intellectual property issues surrounding the original drug may be complex and from a commercial point of view it may not always make sense to take such a drug to market.Drug repositioning has been growing in importance in the last few years as an increasing number of drug development and pharmaceutical companies see their drug pipelines drying up and realize that many previously promising technologies have failed to deliver ‘as advertised’. Computational approaches based on virtual screening of comprehensive libraries of approved and other human use compounds against large numbers of protein targets simultaneously have been developed to enhance the efficiency and success rates of drug repositioning, particularly in terms of high-throughput shotgun repurposing.".
- Drug_repositioning wikiPageExternalLink www.cureswithinreach.org.
- Drug_repositioning wikiPageExternalLink www.fda.gov.
- Drug_repositioning wikiPageExternalLink S1359644614002530.
- Drug_repositioning wikiPageID "18657630".
- Drug_repositioning wikiPageLength "9859".
- Drug_repositioning wikiPageOutDegree "40".
- Drug_repositioning wikiPageRevisionID "698256772".
- Drug_repositioning wikiPageWikiLink Anxiety.
- Drug_repositioning wikiPageWikiLink Autoimmune_lymphoproliferative_syndrome.
- Drug_repositioning wikiPageWikiLink Biovista.
- Drug_repositioning wikiPageWikiLink Buprenorphine.
- Drug_repositioning wikiPageWikiLink CD34.
- Drug_repositioning wikiPageWikiLink CXCR4.
- Drug_repositioning wikiPageWikiLink Category:Drug_discovery.
- Drug_repositioning wikiPageWikiLink Category:Pharmaceutical_industry.
- Drug_repositioning wikiPageWikiLink Celgene.
- Drug_repositioning wikiPageWikiLink Chemical_compound.
- Drug_repositioning wikiPageWikiLink Colesevelam.
- Drug_repositioning wikiPageWikiLink Dihydroetorphine.
- Drug_repositioning wikiPageWikiLink Disease.
- Drug_repositioning wikiPageWikiLink Drug_development.
- Drug_repositioning wikiPageWikiLink Erectile_dysfunction.
- Drug_repositioning wikiPageWikiLink Etorphine.
- Drug_repositioning wikiPageWikiLink Familial_dysautonomia.
- Drug_repositioning wikiPageWikiLink Fentanyl.
- Drug_repositioning wikiPageWikiLink GVK_(conglomerate).
- Drug_repositioning wikiPageWikiLink Gabapentin.
- Drug_repositioning wikiPageWikiLink Half-life.
- Drug_repositioning wikiPageWikiLink Heroin.
- Drug_repositioning wikiPageWikiLink Hydromorphone.
- Drug_repositioning wikiPageWikiLink Inverse_benefit_law.
- Drug_repositioning wikiPageWikiLink Ligand_(biochemistry).
- Drug_repositioning wikiPageWikiLink Melior_Discovery.
- Drug_repositioning wikiPageWikiLink Morphine.
- Drug_repositioning wikiPageWikiLink Opioid.
- Drug_repositioning wikiPageWikiLink Oxycodone.
- Drug_repositioning wikiPageWikiLink Pfizer.
- Drug_repositioning wikiPageWikiLink Pharmaceutical_drug.
- Drug_repositioning wikiPageWikiLink Pharmaceutical_industry.
- Drug_repositioning wikiPageWikiLink Plerixafor.
- Drug_repositioning wikiPageWikiLink Pregabalin.
- Drug_repositioning wikiPageWikiLink Ropinirole.
- Drug_repositioning wikiPageWikiLink Sildenafil.
- Drug_repositioning wikiPageWikiLink Thalidomide.
- Drug_repositioning wikiPageWikiLink Toxicity.
- Drug_repositioning wikiPageWikiLinkText "Drug repositioning".
- Drug_repositioning wikiPageWikiLinkText "drug repositioning".
- Drug_repositioning wikiPageWikiLinkText "re-purposed older drugs".
- Drug_repositioning wikiPageUsesTemplate Template:Citation_needed.
- Drug_repositioning wikiPageUsesTemplate Template:Cite_journal.
- Drug_repositioning wikiPageUsesTemplate Template:Cite_web.
- Drug_repositioning wikiPageUsesTemplate Template:Refbegin.
- Drug_repositioning wikiPageUsesTemplate Template:Refend.
- Drug_repositioning wikiPageUsesTemplate Template:Reflist.
- Drug_repositioning subject Category:Drug_discovery.
- Drug_repositioning subject Category:Pharmaceutical_industry.
- Drug_repositioning hypernym Application.
- Drug_repositioning type Software.
- Drug_repositioning type Industry.
- Drug_repositioning type Pharmaceutic.
- Drug_repositioning type Science.
- Drug_repositioning comment "Drug repositioning (also known as drug repurposing, re-profiling, re-tasking or therapeutic switching) is the application of known drugs and compounds to new indications (i.e., new diseases).A significant advantage of drug repositioning over traditional drug development is that since the repositioned drug has already passed a significant number of toxicity and other tests, its safety is known and the risk of failure for reasons of adverse toxicology are reduced.".
- Drug_repositioning label "Drug repositioning".
- Drug_repositioning sameAs Q5308921.
- Drug_repositioning sameAs Επαναστόχευση_φαρμάκων.
- Drug_repositioning sameAs ドラッグリポジショニング.
- Drug_repositioning sameAs m.04gmx7p.
- Drug_repositioning sameAs Q5308921.
- Drug_repositioning wasDerivedFrom Drug_repositioning?oldid=698256772.
- Drug_repositioning isPrimaryTopicOf Drug_repositioning.