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- Dispersin_B abstract "Dispersin B (also known as DspB or DispersinB) is a 40 kDa glycoside hydrolase produced by the periodontal pathogen, Aggregatibacter actinomycetemcomitans. The bacteria secrete Dispersin B to release adherent cells from a mature biofilm colony by disrupting biofilm formation. The enzyme catalyzes the hydrolysis of linear polymers of N-acetyl-D-glucosamines found in the biofilm matrices. Poly-acetyl glucosamines are integral to the structural integrity of the biofilms of various Gram-positive bacteria and Gram-negative bacteria and are referred to as PIA (PNAG,PS/A) in Staphylococcus species and PGA in Escherichia coli. By degrading the biofilm matrix, Dispersin B allows for the release of bacterial cells that can adhere to new surfaces close by and extend the biofilm or start new colonies. Currently there is interest in Dispersin B as a commercial anti-biofilm agent that could be combined with antibiotics for the treatment of bacterial infections.".
- Dispersin_B ecNumber "3.2.1.52".
- Dispersin_B thumbnail DispB.jpeg?width=300.
- Dispersin_B wikiPageExternalLink dispersinb.htm.
- Dispersin_B wikiPageID "20834652".
- Dispersin_B wikiPageLength "14598".
- Dispersin_B wikiPageOutDegree "23".
- Dispersin_B wikiPageRevisionID "706104654".
- Dispersin_B wikiPageWikiLink Aggregatibacter_actinomycetemcomitans.
- Dispersin_B wikiPageWikiLink Carbamate.
- Dispersin_B wikiPageWikiLink Catalysis.
- Dispersin_B wikiPageWikiLink Category:EC_3.2.1.
- Dispersin_B wikiPageWikiLink Catheter.
- Dispersin_B wikiPageWikiLink Chlorhexidine.
- Dispersin_B wikiPageWikiLink Degree_of_polymerization.
- Dispersin_B wikiPageWikiLink Escherichia_coli.
- Dispersin_B wikiPageWikiLink Glycoside_hydrolase.
- Dispersin_B wikiPageWikiLink Gram-negative_bacteria.
- Dispersin_B wikiPageWikiLink Gram-positive_bacteria.
- Dispersin_B wikiPageWikiLink High-performance_liquid_chromatography.
- Dispersin_B wikiPageWikiLink Hydrolysis.
- Dispersin_B wikiPageWikiLink Periodontal_pathogen.
- Dispersin_B wikiPageWikiLink Ribbon_diagram.
- Dispersin_B wikiPageWikiLink Staphylococcus.
- Dispersin_B wikiPageWikiLink Sulfadiazine.
- Dispersin_B wikiPageWikiLink TIM_barrel.
- Dispersin_B wikiPageWikiLink Triclosan.
- Dispersin_B wikiPageWikiLink File:Active_Site_of_Dispersin_B.png.
- Dispersin_B wikiPageWikiLink File:DispersinB_Mechanism.png.
- Dispersin_B wikiPageWikiLink File:PNAG.png.
- Dispersin_B wikiPageWikiLink File:Single_Domain_of_Dispersin_B.png.
- Dispersin_B wikiPageWikiLinkText "dispersin B".
- Dispersin_B caption "Ribbon diagram of Dispersin B".
- Dispersin_B ecNumber "3.2".
- Dispersin_B ecnumber "3.2".
- Dispersin_B name "Dispersin B".
- Dispersin_B pdb "1".
- Dispersin_B refseq "YP_001449721".
- Dispersin_B symbol "DspB".
- Dispersin_B uniprot "Q840G9".
- Dispersin_B width "250".
- Dispersin_B wikiPageUsesTemplate Template:Enzyme.
- Dispersin_B wikiPageUsesTemplate Template:Enzymes.
- Dispersin_B wikiPageUsesTemplate Template:Portal_bar.
- Dispersin_B wikiPageUsesTemplate Template:Reflist.
- Dispersin_B wikiPageUsesTemplate Template:Sugar_hydrolases.
- Dispersin_B subject Category:EC_3.2.1.
- Dispersin_B hypernym Hydrolase.
- Dispersin_B type Biomolecule.
- Dispersin_B type Enzyme.
- Dispersin_B type Chemical.
- Dispersin_B type Thing.
- Dispersin_B type Q206229.
- Dispersin_B type Q8047.
- Dispersin_B comment "Dispersin B (also known as DspB or DispersinB) is a 40 kDa glycoside hydrolase produced by the periodontal pathogen, Aggregatibacter actinomycetemcomitans. The bacteria secrete Dispersin B to release adherent cells from a mature biofilm colony by disrupting biofilm formation. The enzyme catalyzes the hydrolysis of linear polymers of N-acetyl-D-glucosamines found in the biofilm matrices.".
- Dispersin_B label "Dispersin B".
- Dispersin_B sameAs Q5282577.
- Dispersin_B sameAs m.055g_wp.
- Dispersin_B sameAs Q5282577.
- Dispersin_B wasDerivedFrom Dispersin_B?oldid=706104654.
- Dispersin_B depiction DispB.jpeg.
- Dispersin_B isPrimaryTopicOf Dispersin_B.
- Dispersin_B name "Dispersin B".