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- Denoising_Algorithm_based_on_Relevance_network_Topology abstract "Denoising Algorithm based on Relevance network Topology (DART) is an unsupervised algorithm that estimates an activity score for a pathway in a gene expression matrix, following a denoising step. In DART, a weighted average is used where the weights reflect the degree of the nodes in the pruned network. The denoising step removes prior information that is inconsistent with a data set. This strategy substantially improves unsupervised predictions of pathway activity that are based on a prior model, which was learned from a different biological system or context.Pre-existing methods such as gene set enrichment analysis method attempt to infer. However, it did not construct a structured list of genes. SPIA (Signaling Pathway Impact analysis) is a method that uses the phenotype information to evaluate the pathway activity between two phenotypes. However, it does not identify the pathway gene subset that could be used to differentiate individual samples.CORG is used to identify a relevant gene subset. It is a supervised method, which does not perform as well as DART in analyzing independent data setUnderstanding molecular pathway activity is crucial for risk assessment, clinical diagnosis and treatment. Meta-analysis of complex genomic data is often associated with difficulties such as extracting useful information from big data, eliminating confounding factors and providing more sensible interpretation. Different approaches have been taken to highlight the identification of relevant pathway in order to provide better gene expression prediction.".
- Denoising_Algorithm_based_on_Relevance_network_Topology wikiPageID "42451659".
- Denoising_Algorithm_based_on_Relevance_network_Topology wikiPageLength "6830".
- Denoising_Algorithm_based_on_Relevance_network_Topology wikiPageOutDegree "8".
- Denoising_Algorithm_based_on_Relevance_network_Topology wikiPageRevisionID "701621691".
- Denoising_Algorithm_based_on_Relevance_network_Topology wikiPageWikiLink Algorithm.
- Denoising_Algorithm_based_on_Relevance_network_Topology wikiPageWikiLink CORG.
- Denoising_Algorithm_based_on_Relevance_network_Topology wikiPageWikiLink Category:Computational_biology.
- Denoising_Algorithm_based_on_Relevance_network_Topology wikiPageWikiLink Estrogen_receptor_alpha.
- Denoising_Algorithm_based_on_Relevance_network_Topology wikiPageWikiLink Fisher_transformation.
- Denoising_Algorithm_based_on_Relevance_network_Topology wikiPageWikiLink Gene_expression.
- Denoising_Algorithm_based_on_Relevance_network_Topology wikiPageWikiLink Mammography.
- Denoising_Algorithm_based_on_Relevance_network_Topology wikiPageWikiLink Meta-analysis.
- Denoising_Algorithm_based_on_Relevance_network_Topology wikiPageUsesTemplate Template:Multiple_issues.
- Denoising_Algorithm_based_on_Relevance_network_Topology wikiPageUsesTemplate Template:Notability.
- Denoising_Algorithm_based_on_Relevance_network_Topology wikiPageUsesTemplate Template:Orphan.
- Denoising_Algorithm_based_on_Relevance_network_Topology wikiPageUsesTemplate Template:Reflist.
- Denoising_Algorithm_based_on_Relevance_network_Topology subject Category:Computational_biology.
- Denoising_Algorithm_based_on_Relevance_network_Topology hypernym Algorithm.
- Denoising_Algorithm_based_on_Relevance_network_Topology type Software.
- Denoising_Algorithm_based_on_Relevance_network_Topology comment "Denoising Algorithm based on Relevance network Topology (DART) is an unsupervised algorithm that estimates an activity score for a pathway in a gene expression matrix, following a denoising step. In DART, a weighted average is used where the weights reflect the degree of the nodes in the pruned network. The denoising step removes prior information that is inconsistent with a data set.".
- Denoising_Algorithm_based_on_Relevance_network_Topology label "Denoising Algorithm based on Relevance network Topology".
- Denoising_Algorithm_based_on_Relevance_network_Topology sameAs m.012hfg_9.
- Denoising_Algorithm_based_on_Relevance_network_Topology wasDerivedFrom Denoising_Algorithm_based_on_Relevance_network_Topology?oldid=701621691.
- Denoising_Algorithm_based_on_Relevance_network_Topology isPrimaryTopicOf Denoising_Algorithm_based_on_Relevance_network_Topology.