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- DNA_damage_theory_of_aging abstract "The DNA damage theory of aging proposes that aging is a consequence of unrepaired accumulation of naturally occurring DNA damages. Damage in this context is a DNA alteration that has an abnormal structure. Although both mitochondrial and nuclear DNA damage can contribute to aging, nuclear DNA is the main subject of this analysis. Nuclear DNA damage can contribute to aging either indirectly (by increasing apoptosis or cellular senescence) or directly (by increasing cell dysfunction).In humans and other mammals, DNA damage occurs frequently and DNA repair processes have evolved to compensate. In estimates made for mice, on average approximately 1,500 to 7,000 DNA lesions occur per hour in each mouse cell, or about 36,000 to 160,000 per cell per day. In any cell some DNA damage may remain despite the action of repair processes. The accumulation of unrepaired DNA damage is more prevalent in certain types of cells, particularly in non-replicating or slowly replicating cells, such as cells in the brain, skeletal and cardiac muscle.".
- DNA_damage_theory_of_aging wikiPageID "17062920".
- DNA_damage_theory_of_aging wikiPageLength "39698".
- DNA_damage_theory_of_aging wikiPageOutDegree "65".
- DNA_damage_theory_of_aging wikiPageRevisionID "698475368".
- DNA_damage_theory_of_aging wikiPageWikiLink 8-Oxo-2-deoxyguanosine.
- DNA_damage_theory_of_aging wikiPageWikiLink Ageing.
- DNA_damage_theory_of_aging wikiPageWikiLink Aging_brain.
- DNA_damage_theory_of_aging wikiPageWikiLink Apoptosis.
- DNA_damage_theory_of_aging wikiPageWikiLink Ataxia_telangiectasia.
- DNA_damage_theory_of_aging wikiPageWikiLink Base_excision_repair.
- DNA_damage_theory_of_aging wikiPageWikiLink Biological_immortality.
- DNA_damage_theory_of_aging wikiPageWikiLink Bloom_syndrome.
- DNA_damage_theory_of_aging wikiPageWikiLink Calorie_restriction.
- DNA_damage_theory_of_aging wikiPageWikiLink Cancer.
- DNA_damage_theory_of_aging wikiPageWikiLink Category:Ageing.
- DNA_damage_theory_of_aging wikiPageWikiLink Category:DNA.
- DNA_damage_theory_of_aging wikiPageWikiLink Category:Programmed_cell_death.
- DNA_damage_theory_of_aging wikiPageWikiLink Category:Proximate_theories_of_biological_aging.
- DNA_damage_theory_of_aging wikiPageWikiLink Category:Senescence.
- DNA_damage_theory_of_aging wikiPageWikiLink Category:Theories_of_aging.
- DNA_damage_theory_of_aging wikiPageWikiLink Category:Theories_of_biological_aging.
- DNA_damage_theory_of_aging wikiPageWikiLink Cell_(biology).
- DNA_damage_theory_of_aging wikiPageWikiLink Cell_division.
- DNA_damage_theory_of_aging wikiPageWikiLink Cell_nucleus.
- DNA_damage_theory_of_aging wikiPageWikiLink Cockayne_syndrome.
- DNA_damage_theory_of_aging wikiPageWikiLink DNA_damage_(naturally_occurring).
- DNA_damage_theory_of_aging wikiPageWikiLink DNA_repair.
- DNA_damage_theory_of_aging wikiPageWikiLink DNA_repair-deficiency_disorder.
- DNA_damage_theory_of_aging wikiPageWikiLink Evolution_of_ageing.
- DNA_damage_theory_of_aging wikiPageWikiLink Fanconi_anemia.
- DNA_damage_theory_of_aging wikiPageWikiLink G0_phase.
- DNA_damage_theory_of_aging wikiPageWikiLink Hayflick_limit.
- DNA_damage_theory_of_aging wikiPageWikiLink Kidney.
- DNA_damage_theory_of_aging wikiPageWikiLink Ku70.
- DNA_damage_theory_of_aging wikiPageWikiLink Ku80.
- DNA_damage_theory_of_aging wikiPageWikiLink Ku_(protein).
- DNA_damage_theory_of_aging wikiPageWikiLink Life_expectancy.
- DNA_damage_theory_of_aging wikiPageWikiLink Liver.
- DNA_damage_theory_of_aging wikiPageWikiLink Longevity.
- DNA_damage_theory_of_aging wikiPageWikiLink Maximum_life_span.
- DNA_damage_theory_of_aging wikiPageWikiLink Mitochondrion.
- DNA_damage_theory_of_aging wikiPageWikiLink Muscle.
- DNA_damage_theory_of_aging wikiPageWikiLink Mutation.
- DNA_damage_theory_of_aging wikiPageWikiLink Nijmegen_breakage_syndrome.
- DNA_damage_theory_of_aging wikiPageWikiLink Non-homologous_end_joining.
- DNA_damage_theory_of_aging wikiPageWikiLink Progeria.
- DNA_damage_theory_of_aging wikiPageWikiLink Reactive_oxygen_species.
- DNA_damage_theory_of_aging wikiPageWikiLink Rejuvenation_(aging).
- DNA_damage_theory_of_aging wikiPageWikiLink Rothmund–Thomson_syndrome.
- DNA_damage_theory_of_aging wikiPageWikiLink Senescence.
- DNA_damage_theory_of_aging wikiPageWikiLink Skeletal_muscle.
- DNA_damage_theory_of_aging wikiPageWikiLink Stem_cell.
- DNA_damage_theory_of_aging wikiPageWikiLink Stem_cell_theory_of_aging.
- DNA_damage_theory_of_aging wikiPageWikiLink Telomere.
- DNA_damage_theory_of_aging wikiPageWikiLink Trichothiodystrophy.
- DNA_damage_theory_of_aging wikiPageWikiLink Werner_syndrome.
- DNA_damage_theory_of_aging wikiPageWikiLink Xeroderma_pigmentosum.
- DNA_damage_theory_of_aging wikiPageWikiLinkText "DNA damage theory of ageing".
- DNA_damage_theory_of_aging wikiPageWikiLinkText "DNA damage theory of aging".
- DNA_damage_theory_of_aging wikiPageWikiLinkText "DNA damage theory of aging#Mutation theories of aging".
- DNA_damage_theory_of_aging wikiPageWikiLinkText "DNA damage".
- DNA_damage_theory_of_aging wikiPageWikiLinkText "damage DNA".
- DNA_damage_theory_of_aging wikiPageWikiLinkText "damage to DNA".
- DNA_damage_theory_of_aging wikiPageUsesTemplate Template:Further2.
- DNA_damage_theory_of_aging wikiPageUsesTemplate Template:Senescence.
- DNA_damage_theory_of_aging subject Category:Ageing.
- DNA_damage_theory_of_aging subject Category:DNA.
- DNA_damage_theory_of_aging subject Category:Programmed_cell_death.
- DNA_damage_theory_of_aging subject Category:Proximate_theories_of_biological_aging.
- DNA_damage_theory_of_aging subject Category:Senescence.
- DNA_damage_theory_of_aging subject Category:Theories_of_aging.
- DNA_damage_theory_of_aging subject Category:Theories_of_biological_aging.
- DNA_damage_theory_of_aging hypernym Consequence.
- DNA_damage_theory_of_aging type Disease.
- DNA_damage_theory_of_aging type Process.
- DNA_damage_theory_of_aging type Theory.
- DNA_damage_theory_of_aging comment "The DNA damage theory of aging proposes that aging is a consequence of unrepaired accumulation of naturally occurring DNA damages. Damage in this context is a DNA alteration that has an abnormal structure. Although both mitochondrial and nuclear DNA damage can contribute to aging, nuclear DNA is the main subject of this analysis.".
- DNA_damage_theory_of_aging label "DNA damage theory of aging".
- DNA_damage_theory_of_aging sameAs Q5205751.
- DNA_damage_theory_of_aging sameAs m.0417458.
- DNA_damage_theory_of_aging sameAs Q5205751.
- DNA_damage_theory_of_aging wasDerivedFrom DNA_damage_theory_of_aging?oldid=698475368.
- DNA_damage_theory_of_aging isPrimaryTopicOf DNA_damage_theory_of_aging.