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- DEPT_(medicine) abstract "Directed Enzyme Prodrug Therapy (DEPT) uses enzymes artificially introduced into the body to convert Prodrugs, which have no or poor biological activity, to the active form in the desired location within the body. Many chemotherapy drugs for cancer lack tumour specificity and the doses required to reach therapeutic levels in the tumour are often toxic to other tissues. DEPT strategies are an experimental method of reducing the systemic toxicity of a drug, by achieving high levels of the active drug only at the desired site. This article describes the variations of DEPT technology.".
- DEPT_(medicine) wikiPageID "39150695".
- DEPT_(medicine) wikiPageLength "11244".
- DEPT_(medicine) wikiPageOutDegree "32".
- DEPT_(medicine) wikiPageRevisionID "708044147".
- DEPT_(medicine) wikiPageWikiLink Anaerobic_organism.
- DEPT_(medicine) wikiPageWikiLink Antigen.
- DEPT_(medicine) wikiPageWikiLink Beta-lactamase.
- DEPT_(medicine) wikiPageWikiLink Blood.
- DEPT_(medicine) wikiPageWikiLink Breast_cancer.
- DEPT_(medicine) wikiPageWikiLink Category:Biotechnology.
- DEPT_(medicine) wikiPageWikiLink Category:Experimental_cancer_treatments.
- DEPT_(medicine) wikiPageWikiLink Charing_Cross_Hospital.
- DEPT_(medicine) wikiPageWikiLink Chemotherapy.
- DEPT_(medicine) wikiPageWikiLink Choriocarcinoma.
- DEPT_(medicine) wikiPageWikiLink Ciclosporin.
- DEPT_(medicine) wikiPageWikiLink Clostridia.
- DEPT_(medicine) wikiPageWikiLink Cytosine_deaminase.
- DEPT_(medicine) wikiPageWikiLink Cytotoxicity.
- DEPT_(medicine) wikiPageWikiLink DEPT_(medicine).
- DEPT_(medicine) wikiPageWikiLink Enzyme.
- DEPT_(medicine) wikiPageWikiLink London.
- DEPT_(medicine) wikiPageWikiLink Management_of_cancer.
- DEPT_(medicine) wikiPageWikiLink N-(2-Hydroxypropyl)_methacrylamide.
- DEPT_(medicine) wikiPageWikiLink Neoplasm.
- DEPT_(medicine) wikiPageWikiLink Nitroreductase.
- DEPT_(medicine) wikiPageWikiLink Oncolytic_virus.
- DEPT_(medicine) wikiPageWikiLink Oxygen.
- DEPT_(medicine) wikiPageWikiLink Polymer-drug_conjugates.
- DEPT_(medicine) wikiPageWikiLink Prodrug.
- DEPT_(medicine) wikiPageWikiLink Royal_Free_Hospital.
- DEPT_(medicine) wikiPageWikiLink Suicide_gene.
- DEPT_(medicine) wikiPageWikiLink Tumor_hypoxia.
- DEPT_(medicine) wikiPageWikiLinkText "DEPT (medicine)".
- DEPT_(medicine) wikiPageWikiLinkText "DEPT (medicine)#Gene-directed enzyme prodrug therapy (GDEPT)".
- DEPT_(medicine) wikiPageWikiLinkText "DEPT (medicine)#Virus-directed enzyme prodrug therapy (VDEPT)".
- DEPT_(medicine) wikiPageWikiLinkText "DEPT_(medicine)".
- DEPT_(medicine) wikiPageWikiLinkText "Gene-directed enzyme-producing therapy (GDEPT)".
- DEPT_(medicine) wikiPageWikiLinkText "PDEPT".
- DEPT_(medicine) wikiPageWikiLinkText "virus-directed enzyme-prodrug therapy".
- DEPT_(medicine) wikiPageUsesTemplate Template:Expand_section.
- DEPT_(medicine) wikiPageUsesTemplate Template:Reflist.
- DEPT_(medicine) subject Category:Biotechnology.
- DEPT_(medicine) subject Category:Experimental_cancer_treatments.
- DEPT_(medicine) type Classification.
- DEPT_(medicine) type Redirect.
- DEPT_(medicine) comment "Directed Enzyme Prodrug Therapy (DEPT) uses enzymes artificially introduced into the body to convert Prodrugs, which have no or poor biological activity, to the active form in the desired location within the body. Many chemotherapy drugs for cancer lack tumour specificity and the doses required to reach therapeutic levels in the tumour are often toxic to other tissues.".
- DEPT_(medicine) label "DEPT (medicine)".
- DEPT_(medicine) sameAs Q5009918.
- DEPT_(medicine) sameAs m.02qlk1h.
- DEPT_(medicine) sameAs Q5009918.
- DEPT_(medicine) wasDerivedFrom DEPT_(medicine)?oldid=708044147.
- DEPT_(medicine) isPrimaryTopicOf DEPT_(medicine).