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- Cyanodothiepin abstract "Cyanodothiepin (developmental code name BTS-56,424) is a tricyclic antidepressant (TCA) acting as a potent and highly selective (over norepinephrine and dopamine uptake) inhibitor of the reuptake of serotonin that was never marketed. It also has moderate affinity for the mACh receptors and weak/negligible affinity for the α1-adrenergic, 5-HT2A, D1, and D2 receptors; the H1 receptor has not been assayed, but cyanodothiepin is less sedating than the related drug cianopramine, suggesting its antihistamine activity is not as pronounced as other TCAs. Cyanodothiepin is active in the forced swimming test (FST), inferring that it may possess antidepressant properties in humans. However, it is only weakly active compared to cianopramine and imipramine in monoamine depletion-based tests of antidepressant potential.".
- Cyanodothiepin atcPrefix "None".
- Cyanodothiepin casNumber "90667-37-1".
- Cyanodothiepin iupacName "11-(3-(Dimethylamino)propylidene)-6,11-dihydrodibenzo[b,e]thiepine-2-carbonitrile".
- Cyanodothiepin thumbnail Cyanodothiepin.svg?width=300.
- Cyanodothiepin wikiPageID "33870282".
- Cyanodothiepin wikiPageLength "3927".
- Cyanodothiepin wikiPageOutDegree "28".
- Cyanodothiepin wikiPageRevisionID "699675914".
- Cyanodothiepin wikiPageWikiLink 5-HT2A_receptor.
- Cyanodothiepin wikiPageWikiLink Alpha-1_adrenergic_receptor.
- Cyanodothiepin wikiPageWikiLink Antidepressant.
- Cyanodothiepin wikiPageWikiLink Antihistamine.
- Cyanodothiepin wikiPageWikiLink Behavioural_despair_test.
- Cyanodothiepin wikiPageWikiLink Binding_selectivity.
- Cyanodothiepin wikiPageWikiLink Biological_activity.
- Cyanodothiepin wikiPageWikiLink Category:H1_receptor_antagonists.
- Cyanodothiepin wikiPageWikiLink Category:Muscarinic_antagonists.
- Cyanodothiepin wikiPageWikiLink Category:Selective_serotonin_reuptake_inhibitors.
- Cyanodothiepin wikiPageWikiLink Category:Tricyclic_antidepressants.
- Cyanodothiepin wikiPageWikiLink Cianopramine.
- Cyanodothiepin wikiPageWikiLink Clomipramine.
- Cyanodothiepin wikiPageWikiLink Dopamine.
- Cyanodothiepin wikiPageWikiLink Dopamine_receptor_D1.
- Cyanodothiepin wikiPageWikiLink Dopamine_receptor_D2.
- Cyanodothiepin wikiPageWikiLink Histamine_H1_receptor.
- Cyanodothiepin wikiPageWikiLink Imipramine.
- Cyanodothiepin wikiPageWikiLink Ligand_(biochemistry).
- Cyanodothiepin wikiPageWikiLink Monoamine_neurotransmitter.
- Cyanodothiepin wikiPageWikiLink Muscarinic_acetylcholine_receptor.
- Cyanodothiepin wikiPageWikiLink Norepinephrine.
- Cyanodothiepin wikiPageWikiLink Potency_(pharmacology).
- Cyanodothiepin wikiPageWikiLink Reuptake.
- Cyanodothiepin wikiPageWikiLink Reuptake_inhibitor.
- Cyanodothiepin wikiPageWikiLink Sedative.
- Cyanodothiepin wikiPageWikiLink Serotonin.
- Cyanodothiepin wikiPageWikiLink Tricyclic_antidepressant.
- Cyanodothiepin wikiPageWikiLinkText "Cyanodothiepin".
- Cyanodothiepin atcPrefix "None".
- Cyanodothiepin c "20".
- Cyanodothiepin casNumber "90667".
- Cyanodothiepin chemspiderid "30780728".
- Cyanodothiepin h "20".
- Cyanodothiepin inchi "1".
- Cyanodothiepin inchikey "FSIRGTNPQFDCCD-QGMBQPNBBO".
- Cyanodothiepin iupacName "11".
- Cyanodothiepin molecularWeight "320.45".
- Cyanodothiepin n "2".
- Cyanodothiepin s "1".
- Cyanodothiepin smiles "CNCC/C=C1C2=CSCC3=C/1C=CC=C3".
- Cyanodothiepin stdinchi "1".
- Cyanodothiepin stdinchikey "FSIRGTNPQFDCCD-QGMBQPNBSA-N".
- Cyanodothiepin wikiPageUsesTemplate Template:Antidepressants.
- Cyanodothiepin wikiPageUsesTemplate Template:Cholinergics.
- Cyanodothiepin wikiPageUsesTemplate Template:Drugbox.
- Cyanodothiepin wikiPageUsesTemplate Template:Histaminergics.
- Cyanodothiepin wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- Cyanodothiepin wikiPageUsesTemplate Template:Reflist.
- Cyanodothiepin wikiPageUsesTemplate Template:Serotonergics.
- Cyanodothiepin wikiPageUsesTemplate Template:Tricyclics.
- Cyanodothiepin subject Category:H1_receptor_antagonists.
- Cyanodothiepin subject Category:Muscarinic_antagonists.
- Cyanodothiepin subject Category:Selective_serotonin_reuptake_inhibitors.
- Cyanodothiepin subject Category:Tricyclic_antidepressants.
- Cyanodothiepin hypernym Antidepressant.
- Cyanodothiepin type ChemicalSubstance.
- Cyanodothiepin type Drug.
- Cyanodothiepin type Antagonist.
- Cyanodothiepin type Antidepressant.
- Cyanodothiepin type Antihistamine.
- Cyanodothiepin type Chemical.
- Cyanodothiepin type Drug.
- Cyanodothiepin type Inhibitor.
- Cyanodothiepin type ChemicalObject.
- Cyanodothiepin type Thing.
- Cyanodothiepin type Q8386.
- Cyanodothiepin comment "Cyanodothiepin (developmental code name BTS-56,424) is a tricyclic antidepressant (TCA) acting as a potent and highly selective (over norepinephrine and dopamine uptake) inhibitor of the reuptake of serotonin that was never marketed.".
- Cyanodothiepin label "Cyanodothiepin".
- Cyanodothiepin sameAs Q5197458.
- Cyanodothiepin sameAs m.0hn95jk.
- Cyanodothiepin sameAs Cijanodotiepin.
- Cyanodothiepin sameAs Cijanodotiepin.
- Cyanodothiepin sameAs Q5197458.
- Cyanodothiepin wasDerivedFrom Cyanodothiepin?oldid=699675914.
- Cyanodothiepin depiction Cyanodothiepin.svg.
- Cyanodothiepin isPrimaryTopicOf Cyanodothiepin.