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- Curacin_A abstract "Curacin A is a hybrid Polyketide Synthase(PKS) Non-Ribosomal Peptide Synthase(NRPS) derived natural product produced by and isolated from the cyanobacterium Lyngya Majuscula. Curacin A belongs to a family of natural products including jamaicamide, mupriocin, and pederin that have an unusual terminal alkene. Additionally, Curacin A contains a notable thiazoline ring and a unique cyclopropyl moiety, which is essential to the compound's biological activity. Curacin A has been characterized as potent antiproliferative cytotoxic compound with notable anticancer activity for several cancer lines including renal, colon, and breast cancer. Curacin A has been shown to interact with colchicine binding sites on tubulin, which inhibits microtubule polymerization, an essential process for cell division and proliferation.".
- Curacin_A iupacName "(4R)-4-[(1Z,5E,7E,11R)-11-Methoxy-8-methyl-1,5,7,13-tetradecatetraen-1-yl]-2-[(1R,2S)-2-methylcyclopropyl]-4,5-dihydro-1,3-thiazol".
- Curacin_A pubchem "5281967".
- Curacin_A wikiPageID "46946757".
- Curacin_A wikiPageLength "7164".
- Curacin_A wikiPageOutDegree "3".
- Curacin_A wikiPageRevisionID "705728015".
- Curacin_A wikiPageWikiLink Category:Lyases.
- Curacin_A wikiPageWikiLink File:CuracinA_Biosynthetic_Pathway.pdf.
- Curacin_A wikiPageWikiLink File:CuracinA_Cyclopropyl_Moiety_Biosynthesis.pdf.
- Curacin_A wikiPageWikiLinkText "curacin A".
- Curacin_A c "23".
- Curacin_A chemspiderid "4445239".
- Curacin_A h "35".
- Curacin_A inchi "1".
- Curacin_A inchikey "LUEYTMPPCOCKBX-KWYHTCOPBB".
- Curacin_A iupacName "-4".
- Curacin_A n "1".
- Curacin_A o "1".
- Curacin_A pubchem "5281967".
- Curacin_A s "1".
- Curacin_A smiles "C[C@H]1C[C@H]1C2=N[C@@H]/C=C\CC/C=C/C=C/CC[C@H]OC".
- Curacin_A stdinchi "1".
- Curacin_A stdinchikey "LUEYTMPPCOCKBX-KWYHTCOPSA-N".
- Curacin_A verifiedrevid "464189839".
- Curacin_A width "300".
- Curacin_A wikiPageUsesTemplate Template:Drugbox.
- Curacin_A wikiPageUsesTemplate Template:Reflist.
- Curacin_A wikiPageUsesTemplate Template:Underlinked.
- Curacin_A subject Category:Lyases.
- Curacin_A hypernym Synthase.
- Curacin_A type ChemicalSubstance.
- Curacin_A type Drug.
- Curacin_A type ChemicalObject.
- Curacin_A type Thing.
- Curacin_A type Q8386.
- Curacin_A comment "Curacin A is a hybrid Polyketide Synthase(PKS) Non-Ribosomal Peptide Synthase(NRPS) derived natural product produced by and isolated from the cyanobacterium Lyngya Majuscula. Curacin A belongs to a family of natural products including jamaicamide, mupriocin, and pederin that have an unusual terminal alkene. Additionally, Curacin A contains a notable thiazoline ring and a unique cyclopropyl moiety, which is essential to the compound's biological activity.".
- Curacin_A label "Curacin A".
- Curacin_A sameAs m.013dc22s.
- Curacin_A wasDerivedFrom Curacin_A?oldid=705728015.
- Curacin_A isPrimaryTopicOf Curacin_A.