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- CpG_Oligodeoxynucleotide abstract "CpG oligodeoxynucleotides (or CpG ODN) are short single-stranded synthetic DNA molecules that contain a cytosine triphosphate deoxynucleotide (\"C\") followed by a guanine triphosphate deoxynucleotide (\"G\"). The \"p\" refers to the phosphodiester link between consecutive nucleotides, although some ODN have a modified phosphorothioate (PS) backbone instead. When these CpG motifs are unmethylated, they act as immunostimulants. CpG motifs are considered pathogen-associated molecular patterns (PAMPs) due to their abundance in microbial genomes but their rarity in vertebrate genomes. The CpG PAMP is recognized by the pattern recognition receptor (PRR) Toll-Like Receptor 9 (TLR9), which is constitutively expressed only in B cells and plasmacytoid dendritic cells (pDCs) in humans and other higher primates.".
- CpG_Oligodeoxynucleotide thumbnail CpG_ODN_effects.png?width=300.
- CpG_Oligodeoxynucleotide wikiPageID "23780702".
- CpG_Oligodeoxynucleotide wikiPageLength "10935".
- CpG_Oligodeoxynucleotide wikiPageOutDegree "33".
- CpG_Oligodeoxynucleotide wikiPageRevisionID "700895573".
- CpG_Oligodeoxynucleotide wikiPageWikiLink Adjuvant.
- CpG_Oligodeoxynucleotide wikiPageWikiLink B_cell.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Carcinoma.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Category:Immune_system.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Category:Immunostimulants.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Coleys_toxins.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Cytokine.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Cytosine.
- CpG_Oligodeoxynucleotide wikiPageWikiLink DNA.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Dendritic_cell.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Deoxyribonuclease.
- CpG_Oligodeoxynucleotide wikiPageWikiLink File:CpG_ODN_effects.png.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Guanine.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Immunologic_adjuvant.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Immunostimulant.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Inflammation.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Interferon_type_I.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Natural_killer_cell.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Nuclease.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Nucleotide.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Palindrome.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Pathogen-associated_molecular_pattern.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Pattern_recognition_receptor.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Peripheral_blood_mononuclear_cell.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Phosphodiester_bond.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Purine.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Pyrimidine.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Sequence_motif.
- CpG_Oligodeoxynucleotide wikiPageWikiLink TLR9.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Thiophosphate.
- CpG_Oligodeoxynucleotide wikiPageWikiLink Vaccine.
- CpG_Oligodeoxynucleotide wikiPageWikiLinkText "CpG DNA sequences".
- CpG_Oligodeoxynucleotide wikiPageWikiLinkText "CpG Oligodeoxynucleotide".
- CpG_Oligodeoxynucleotide wikiPageWikiLinkText "CpG sequences".
- CpG_Oligodeoxynucleotide wikiPageWikiLinkText "CpG".
- CpG_Oligodeoxynucleotide wikiPageWikiLinkText "unmethlyated CpG motif".
- CpG_Oligodeoxynucleotide wikiPageWikiLinkText "unmethylated CpG dinucleotides".
- CpG_Oligodeoxynucleotide wikiPageWikiLinkText "unmethylated CpG".
- CpG_Oligodeoxynucleotide wikiPageUsesTemplate Template:Confuse.
- CpG_Oligodeoxynucleotide wikiPageUsesTemplate Template:Reflist.
- CpG_Oligodeoxynucleotide subject Category:Immune_system.
- CpG_Oligodeoxynucleotide subject Category:Immunostimulants.
- CpG_Oligodeoxynucleotide hypernym Molecules.
- CpG_Oligodeoxynucleotide type Drug.
- CpG_Oligodeoxynucleotide type Protein.
- CpG_Oligodeoxynucleotide type Drug.
- CpG_Oligodeoxynucleotide type Thing.
- CpG_Oligodeoxynucleotide comment "CpG oligodeoxynucleotides (or CpG ODN) are short single-stranded synthetic DNA molecules that contain a cytosine triphosphate deoxynucleotide (\"C\") followed by a guanine triphosphate deoxynucleotide (\"G\"). The \"p\" refers to the phosphodiester link between consecutive nucleotides, although some ODN have a modified phosphorothioate (PS) backbone instead. When these CpG motifs are unmethylated, they act as immunostimulants.".
- CpG_Oligodeoxynucleotide label "CpG Oligodeoxynucleotide".
- CpG_Oligodeoxynucleotide differentFrom CpG_site.
- CpG_Oligodeoxynucleotide sameAs Q477471.
- CpG_Oligodeoxynucleotide sameAs CpG-Oligonukleotid.
- CpG_Oligodeoxynucleotide sameAs m.06_v6c9.
- CpG_Oligodeoxynucleotide sameAs Q477471.
- CpG_Oligodeoxynucleotide wasDerivedFrom CpG_Oligodeoxynucleotide?oldid=700895573.
- CpG_Oligodeoxynucleotide depiction CpG_ODN_effects.png.
- CpG_Oligodeoxynucleotide isPrimaryTopicOf CpG_Oligodeoxynucleotide.