Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Cotinine> ?p ?o }
- Cotinine abstract "Cotinine is an alkaloid found in tobacco and is also the predominant metabolite of nicotine. The word \"cotinine\" is an anagram of \"nicotine\". Cotinine is used as a biomarker for exposure to tobacco smoke. Cotinine is currently being studied as a treatment for depression, PTSD, schizophrenia, Alzheimer's disease and Parkinson's disease. Cotinine was developed as an antidepressant as a fumaric acid salt, cotinine fumarate, to be sold under the brand name Scotine but it was never marketed.Similarly to nicotine, cotinine binds to, activates, and desensitizes neuronal nicotinic acetylcholine receptors, though at much lower potency in comparison. It has demonstrated nootropic and antipsychotic-like effects in animal models. Cotinine treatment has also been shown to reduce depression, anxiety, and fear-related behavior as well as memory impairment in animal models of depression, PTSD, and Alzheimer's disease. Nonetheless, treatment with cotinine in humans was reported to have no significant physiologic, subjective, or performance effects in one study, though others suggest that this may not be the case.Because cotinine is the main metabolite to nicotine and has been shown to be pharmacologically active, it has been suggested that some of nicotine's effects in the nervous system may be mediated by cotinine and/or complex interactions with nicotine itself.".
- Cotinine atcPrefix "none".
- Cotinine casNumber "486-56-6".
- Cotinine fdaUniiCode "K5161X06LL".
- Cotinine iupacName "(5S)-1-methyl-5-(3-pyridyl)pyrrolidin-2-one".
- Cotinine pubchem "854019".
- Cotinine thumbnail Cotinine2DACS.svg?width=300.
- Cotinine wikiPageID "767086".
- Cotinine wikiPageLength "14487".
- Cotinine wikiPageOutDegree "44".
- Cotinine wikiPageRevisionID "706103809".
- Cotinine wikiPageWikiLink African_Americans.
- Cotinine wikiPageWikiLink Alkaloid.
- Cotinine wikiPageWikiLink Alzheimers_disease.
- Cotinine wikiPageWikiLink Anagram.
- Cotinine wikiPageWikiLink Animal_models_of_depression.
- Cotinine wikiPageWikiLink Antidepressant.
- Cotinine wikiPageWikiLink Antipsychotic.
- Cotinine wikiPageWikiLink Anxiety.
- Cotinine wikiPageWikiLink Biomarker.
- Cotinine wikiPageWikiLink Blood.
- Cotinine wikiPageWikiLink CYP2A6.
- Cotinine wikiPageWikiLink Category:Alkaloids_found_in_Nicotiana.
- Cotinine wikiPageWikiLink Category:Nicotinic_agonists.
- Cotinine wikiPageWikiLink Category:Pyridines.
- Cotinine wikiPageWikiLink Category:Pyrrolidones.
- Cotinine wikiPageWikiLink Category:Recreational_drug_metabolites.
- Cotinine wikiPageWikiLink Depression_(mood).
- Cotinine wikiPageWikiLink Drug_metabolism.
- Cotinine wikiPageWikiLink Electronic_cigarette.
- Cotinine wikiPageWikiLink Fear.
- Cotinine wikiPageWikiLink Fumaric_acid.
- Cotinine wikiPageWikiLink Half-life.
- Cotinine wikiPageWikiLink In_vivo.
- Cotinine wikiPageWikiLink Menthol.
- Cotinine wikiPageWikiLink Metabolite.
- Cotinine wikiPageWikiLink Nicotine.
- Cotinine wikiPageWikiLink Nicotinic_acetylcholine_receptor.
- Cotinine wikiPageWikiLink Nootropic.
- Cotinine wikiPageWikiLink Parkinsons_disease.
- Cotinine wikiPageWikiLink Passive_smoking.
- Cotinine wikiPageWikiLink Posttraumatic_stress_disorder.
- Cotinine wikiPageWikiLink Potency_(pharmacology).
- Cotinine wikiPageWikiLink Saliva.
- Cotinine wikiPageWikiLink Schizophrenia.
- Cotinine wikiPageWikiLink Tobacco.
- Cotinine wikiPageWikiLink Urine.
- Cotinine wikiPageWikiLink White_Americans.
- Cotinine wikiPageWikiLinkText "Cotinine".
- Cotinine wikiPageWikiLinkText "cotinine".
- Cotinine atcPrefix "none".
- Cotinine c "10".
- Cotinine casNumber "486".
- Cotinine chembl "578211".
- Cotinine chemspiderid "746405".
- Cotinine eliminationHalfLife "72000.0".
- Cotinine h "12".
- Cotinine inchi "1".
- Cotinine inchikey "UIKROCXWUNQSPJ-VIFPVBQEBC".
- Cotinine iupacName "-1".
- Cotinine legalStatus "Rx-only".
- Cotinine molecularWeight "176.22".
- Cotinine n "2".
- Cotinine o "1".
- Cotinine pubchem "854019".
- Cotinine routesOfAdministration "Oral, Smoked, Insufflation".
- Cotinine smiles "O=C2N[C@H]CC2".
- Cotinine stdinchi "1".
- Cotinine stdinchikey "UIKROCXWUNQSPJ-VIFPVBQESA-N".
- Cotinine unii "K5161X06LL".
- Cotinine verifiedrevid "414086996".
- Cotinine wikiPageUsesTemplate Template:Cascite.
- Cotinine wikiPageUsesTemplate Template:Chemspidercite.
- Cotinine wikiPageUsesTemplate Template:Cholinergics.
- Cotinine wikiPageUsesTemplate Template:Distinguish.
- Cotinine wikiPageUsesTemplate Template:Drugbox.
- Cotinine wikiPageUsesTemplate Template:Ebicite.
- Cotinine wikiPageUsesTemplate Template:Fdacite.
- Cotinine wikiPageUsesTemplate Template:Nootropics.
- Cotinine wikiPageUsesTemplate Template:Reflist.
- Cotinine wikiPageUsesTemplate Template:Stdinchicite.
- Cotinine wikiPageUsesTemplate Template:Use_dmy_dates.
- Cotinine subject Category:Alkaloids_found_in_Nicotiana.
- Cotinine subject Category:Nicotinic_agonists.
- Cotinine subject Category:Pyridines.
- Cotinine subject Category:Pyrrolidones.
- Cotinine subject Category:Recreational_drug_metabolites.
- Cotinine hypernym Alkaloid.
- Cotinine type ChemicalCompound.
- Cotinine type ChemicalSubstance.
- Cotinine type Drug.
- Cotinine type Agonist.
- Cotinine type Drug.
- Cotinine type Heterocycle.
- Cotinine type Lactam.
- Cotinine type Parasympathomimetic.
- Cotinine type Redirect.
- Cotinine type ChemicalObject.
- Cotinine type Thing.
- Cotinine type Q8386.