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- Cortical_granule abstract "Cortical granules are regulatory secretory organelles (ranging from 0.2 um to 0.6 um in diameter) found within oocytes and are most associated with polyspermy prevention after the event of fertilization. Cortical granules are found among all mammals, many vertebrates, and some invertebrates. Within the oocyte, cortical granules are located along the cortex, the region furthest from the cell's center. Following fertilization, a signaling pathway induces the cortical granules to fuse with the oocyte's cell membrane and release their contents into the oocyte's extracellular matrix. This exocytosis of cortical granules is known as the cortical reaction. In mammals, the oocyte's extracellular matrix includes a surrounding layer of perivitelline space, zona pellucida, and finally cumulus cells. Experimental evidence has demonstrated that the released contents of the cortical granules modify the oocyte's extracellular matrix, particularly the zone pellucida. This alteration of the zona pellucida components is known as the zona reaction. The cortical reaction does not occur in all mammals, suggesting the likelihood of other functional purposes for cortical granules. In addition to modifying the oocyte's extracellular matrix and establishing a block to polyspermy, the exocytosis of cortical granules may also contribute towards protection and support of the developing embryo during preimplantation. Once the cortical granules complete their functions, the oocyte does not replenish them.".
- Cortical_granule thumbnail Cortical_granules.jpg?width=300.
- Cortical_granule wikiPageID "41445162".
- Cortical_granule wikiPageLength "14908".
- Cortical_granule wikiPageOutDegree "48".
- Cortical_granule wikiPageRevisionID "698312730".
- Cortical_granule wikiPageWikiLink Acrosome_reaction.
- Cortical_granule wikiPageWikiLink Actin.
- Cortical_granule wikiPageWikiLink C1QBP.
- Cortical_granule wikiPageWikiLink Calmodulin.
- Cortical_granule wikiPageWikiLink Calreticulin.
- Cortical_granule wikiPageWikiLink Category:Germ_cell_structures.
- Cortical_granule wikiPageWikiLink Category:Secretory_vesicles.
- Cortical_granule wikiPageWikiLink Chaperone_(protein).
- Cortical_granule wikiPageWikiLink Cortical_reaction.
- Cortical_granule wikiPageWikiLink Cumulus_oophorus.
- Cortical_granule wikiPageWikiLink Cytoskeleton.
- Cortical_granule wikiPageWikiLink Diglyceride.
- Cortical_granule wikiPageWikiLink Echinoderm.
- Cortical_granule wikiPageWikiLink Endoplasmic_reticulum.
- Cortical_granule wikiPageWikiLink File:Cortical_granules.jpg.
- Cortical_granule wikiPageWikiLink Gelsolin.
- Cortical_granule wikiPageWikiLink Glycoside_hydrolase.
- Cortical_granule wikiPageWikiLink Glycosylation.
- Cortical_granule wikiPageWikiLink Golgi_apparatus.
- Cortical_granule wikiPageWikiLink Inositol_phosphate.
- Cortical_granule wikiPageWikiLink Inositol_trisphosphate.
- Cortical_granule wikiPageWikiLink Invertebrate.
- Cortical_granule wikiPageWikiLink Mammal.
- Cortical_granule wikiPageWikiLink Meiosis.
- Cortical_granule wikiPageWikiLink Microfilament.
- Cortical_granule wikiPageWikiLink N-Acetylgalactosamine.
- Cortical_granule wikiPageWikiLink N-Acetylglucosamine.
- Cortical_granule wikiPageWikiLink N-Acetyllactosamine.
- Cortical_granule wikiPageWikiLink N-Acetylneuraminic_acid.
- Cortical_granule wikiPageWikiLink N-Glycolylneuraminic_acid.
- Cortical_granule wikiPageWikiLink NAGLU.
- Cortical_granule wikiPageWikiLink Oocyte.
- Cortical_granule wikiPageWikiLink Ovulation.
- Cortical_granule wikiPageWikiLink Perivitelline_space.
- Cortical_granule wikiPageWikiLink Plasmin.
- Cortical_granule wikiPageWikiLink Plasminogen_activator.
- Cortical_granule wikiPageWikiLink Polar_body.
- Cortical_granule wikiPageWikiLink Polyspermy.
- Cortical_granule wikiPageWikiLink Protease.
- Cortical_granule wikiPageWikiLink Protein-arginine_deiminase.
- Cortical_granule wikiPageWikiLink Protein_kinase_C.
- Cortical_granule wikiPageWikiLink Trypsin.
- Cortical_granule wikiPageWikiLink Vertebrate.
- Cortical_granule wikiPageWikiLink Zona_pellucida.
- Cortical_granule wikiPageWikiLinkText "Cortical granule".
- Cortical_granule wikiPageWikiLinkText "cortical granule".
- Cortical_granule wikiPageUsesTemplate Template:Reflist.
- Cortical_granule subject Category:Germ_cell_structures.
- Cortical_granule subject Category:Secretory_vesicles.
- Cortical_granule hypernym Organelles.
- Cortical_granule type AnatomicalStructure.
- Cortical_granule comment "Cortical granules are regulatory secretory organelles (ranging from 0.2 um to 0.6 um in diameter) found within oocytes and are most associated with polyspermy prevention after the event of fertilization. Cortical granules are found among all mammals, many vertebrates, and some invertebrates. Within the oocyte, cortical granules are located along the cortex, the region furthest from the cell's center.".
- Cortical_granule label "Cortical granule".
- Cortical_granule sameAs Q16965740.
- Cortical_granule sameAs m.0ztdbw_.
- Cortical_granule sameAs Q16965740.
- Cortical_granule wasDerivedFrom Cortical_granule?oldid=698312730.
- Cortical_granule depiction Cortical_granules.jpg.
- Cortical_granule isPrimaryTopicOf Cortical_granule.