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- Cholic_acid abstract "Cholic acid, also known as 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid is a primary bile acid that is insoluble in water (soluble in alcohol and acetic acid), it is a white crystalline substance. Salts of cholic acid are called cholates. Cholic acid, along with chenodeoxycholic acid, is one of the two major bile acids produced by the liver, where it is synthesized from cholesterol. These two major bile acids are roughly equal in concentration in humans. Derivatives are made from cholyl-CoA, which exchanges its CoA with either glycine, or taurine, yielding glycocholic and taurocholic acid, respectively.Cholic acid downregulates cholesterol-7-α-hydroxylase (rate-limiting step in bile acid synthesis), and cholesterol does the opposite. This is why chenodeoxycholic acid, and not cholic acid, can be used to treat gallstones (because decreasing bile acid synthesis would supersaturate the stones even more).Cholic acid and chenodeoxycholic acid are the most important human bile acids. Other species may synthesize different bile acids as their predominant primary bile acids.Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug Administration as a treatment for children and adults with bile acid synthesis disorders due to single enzyme defects, and for peroxisomal disorders (such as Zellweger syndrome).".
- Cholic_acid iupacName "(R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-Trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid".
- Cholic_acid thumbnail Cholsäure.svg?width=300.
- Cholic_acid wikiPageID "2984470".
- Cholic_acid wikiPageLength "6045".
- Cholic_acid wikiPageOutDegree "19".
- Cholic_acid wikiPageRevisionID "693134660".
- Cholic_acid wikiPageWikiLink Acetic_acid.
- Cholic_acid wikiPageWikiLink Bile_acid.
- Cholic_acid wikiPageWikiLink Category:Alcohols.
- Cholic_acid wikiPageWikiLink Category:Bile_acids.
- Cholic_acid wikiPageWikiLink Chenodeoxycholic_acid.
- Cholic_acid wikiPageWikiLink Cholesterol.
- Cholic_acid wikiPageWikiLink Coenzyme_A.
- Cholic_acid wikiPageWikiLink Ethanol.
- Cholic_acid wikiPageWikiLink Food_and_Drug_Administration.
- Cholic_acid wikiPageWikiLink Gallstone.
- Cholic_acid wikiPageWikiLink Glycine.
- Cholic_acid wikiPageWikiLink Glycocholic_acid.
- Cholic_acid wikiPageWikiLink Liver.
- Cholic_acid wikiPageWikiLink Taurine.
- Cholic_acid wikiPageWikiLink Taurocholic_acid.
- Cholic_acid wikiPageWikiLink Zellweger_syndrome.
- Cholic_acid wikiPageWikiLink File:Cholic_Acid_vs_Other_Bile_Acids.svg.
- Cholic_acid wikiPageWikiLinkText "Cholate".
- Cholic_acid wikiPageWikiLinkText "Cholic acid".
- Cholic_acid wikiPageWikiLinkText "E1000".
- Cholic_acid wikiPageWikiLinkText "cholic acid".
- Cholic_acid wikiPageWikiLinkText "cholic".
- Cholic_acid imagefile "Cholic acid ball-and-stick.png".
- Cholic_acid imagefile "Cholsäure.svg".
- Cholic_acid imagename "Cholic acid".
- Cholic_acid iupacname "-4".
- Cholic_acid name "Cholic acid".
- Cholic_acid othernames "3".
- Cholic_acid verifiedfields "changed".
- Cholic_acid verifiedrevid "401957444".
- Cholic_acid watchedfields "changed".
- Cholic_acid wikiPageUsesTemplate Template:Authority_control.
- Cholic_acid wikiPageUsesTemplate Template:Bile_and_liver_therapy.
- Cholic_acid wikiPageUsesTemplate Template:Cascite.
- Cholic_acid wikiPageUsesTemplate Template:Chembox.
- Cholic_acid wikiPageUsesTemplate Template:Chembox_Identifiers.
- Cholic_acid wikiPageUsesTemplate Template:Chembox_Pharmacology.
- Cholic_acid wikiPageUsesTemplate Template:Chembox_Properties.
- Cholic_acid wikiPageUsesTemplate Template:Chemspidercite.
- Cholic_acid wikiPageUsesTemplate Template:Drugbankcite.
- Cholic_acid wikiPageUsesTemplate Template:Ebicite.
- Cholic_acid wikiPageUsesTemplate Template:Fdacite.
- Cholic_acid wikiPageUsesTemplate Template:Reflist.
- Cholic_acid wikiPageUsesTemplate Template:StatinPathway_WP430.
- Cholic_acid wikiPageUsesTemplate Template:Stdinchicite.
- Cholic_acid subject Category:Alcohols.
- Cholic_acid subject Category:Bile_acids.
- Cholic_acid hypernym Acid.
- Cholic_acid type ChemicalCompound.
- Cholic_acid type ChemicalSubstance.
- Cholic_acid type Alcohol.
- Cholic_acid type Chemical.
- Cholic_acid type Redirect.
- Cholic_acid type Steroid.
- Cholic_acid type ChemicalObject.
- Cholic_acid type Thing.
- Cholic_acid type Q11173.
- Cholic_acid comment "Cholic acid, also known as 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid is a primary bile acid that is insoluble in water (soluble in alcohol and acetic acid), it is a white crystalline substance. Salts of cholic acid are called cholates. Cholic acid, along with chenodeoxycholic acid, is one of the two major bile acids produced by the liver, where it is synthesized from cholesterol. These two major bile acids are roughly equal in concentration in humans.".
- Cholic_acid label "Cholic acid".
- Cholic_acid sameAs Q287415.
- Cholic_acid sameAs Àcid_còlic.
- Cholic_acid sameAs Kyselina_cholová.
- Cholic_acid sameAs Cholsäure.
- Cholic_acid sameAs Ácido_cólico.
- Cholic_acid sameAs اسید_کولیک.
- Cholic_acid sameAs Acide_cholique.
- Cholic_acid sameAs Ácido_cólico.
- Cholic_acid sameAs חומצה_כולית.
- Cholic_acid sameAs Acido_colico.
- Cholic_acid sameAs コール酸.
- Cholic_acid sameAs Kwas_cholowy.
- Cholic_acid sameAs m.02kcrkf.
- Cholic_acid sameAs Холевая_кислота.
- Cholic_acid sameAs Holna_kiselina.
- Cholic_acid sameAs Holna_kiselina.
- Cholic_acid sameAs Cholsyra.
- Cholic_acid sameAs Q287415.
- Cholic_acid wasDerivedFrom Cholic_acid?oldid=693134660.
- Cholic_acid depiction Cholsäure.svg.
- Cholic_acid isPrimaryTopicOf Cholic_acid.
- Cholic_acid name "Cholic acid".