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- Cetilistat abstract "Cetilistat is a drug designed to treat obesity. It acts in the same way as the older drug orlistat (Xenical) by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine. Without this enzyme, triglycerides from the diet are prevented from being hydrolyzed into absorbable free fatty acids and are excreted undigested.In human trials, cetilistat was shown to produce similar weight loss to orlistat, but also produced similar side effects such as oily, loose stools, fecal incontinence, frequent bowel movements, and flatulence. It is likely that the same precautions would apply in that absorption of fat-soluble vitamins and other fat-soluble nutrients may be inhibited, requiring vitamin supplements to be used to avoid deficiencies.Cetilistat has completed Phase 1 and 2 trials in the West and is currently in Phase 3 trials in Japan where it is partnered with Takeda. Norgina BV has now acquired the full global rights to cetilistat from Alizyme after the latter went into administration.A published phase 2 trial found cetilistat significantly reduced weight with and was better tolerated than orlistat.".
- Cetilistat atcPrefix "none".
- Cetilistat casNumber "282526-98-1".
- Cetilistat fdaUniiCode "LC5G1JUA39".
- Cetilistat iupacName "2-(Hexadecyloxy)-6-methyl-4H-3,1-benzoxazin-4-one".
- Cetilistat pubchem "9952916".
- Cetilistat thumbnail Cetilistat.svg?width=300.
- Cetilistat wikiPageID "19954180".
- Cetilistat wikiPageLength "4795".
- Cetilistat wikiPageOutDegree "16".
- Cetilistat wikiPageRevisionID "701656489".
- Cetilistat wikiPageWikiLink Anti-obesity_medication.
- Cetilistat wikiPageWikiLink Category:Antiobesity_drugs.
- Cetilistat wikiPageWikiLink Category:Benzoxazines.
- Cetilistat wikiPageWikiLink Category:Ethers.
- Cetilistat wikiPageWikiLink Category:Lactones.
- Cetilistat wikiPageWikiLink Enzyme.
- Cetilistat wikiPageWikiLink Fatty_acid.
- Cetilistat wikiPageWikiLink Fecal_incontinence.
- Cetilistat wikiPageWikiLink Flatulence.
- Cetilistat wikiPageWikiLink Gastrointestinal_tract.
- Cetilistat wikiPageWikiLink Hydrolysis.
- Cetilistat wikiPageWikiLink Obesity.
- Cetilistat wikiPageWikiLink Orlistat.
- Cetilistat wikiPageWikiLink Pancreatic_lipase.
- Cetilistat wikiPageWikiLink Triglyceride.
- Cetilistat wikiPageWikiLink Vitamin.
- Cetilistat wikiPageWikiLinkText "Cetilistat".
- Cetilistat wikiPageWikiLinkText "cetilistat".
- Cetilistat atcPrefix "none".
- Cetilistat c "25".
- Cetilistat casNumber "282526".
- Cetilistat chembl "2103825".
- Cetilistat chemspiderid "8128526".
- Cetilistat h "39".
- Cetilistat inchi "1".
- Cetilistat inchikey "MVCQKIKWYUURMU-UHFFFAOYAR".
- Cetilistat iupacName "2".
- Cetilistat kegg "D09208".
- Cetilistat molecularWeight "401.582".
- Cetilistat n "1".
- Cetilistat o "3".
- Cetilistat pubchem "9952916".
- Cetilistat smiles "CCCCCCCCCCCCCCCCOc2occ1ccccc1n2".
- Cetilistat stdinchi "1".
- Cetilistat stdinchikey "MVCQKIKWYUURMU-UHFFFAOYSA-N".
- Cetilistat unii "LC5G1JUA39".
- Cetilistat verifiedfields "changed".
- Cetilistat verifiedrevid "443842048".
- Cetilistat watchedfields "changed".
- Cetilistat width "350".
- Cetilistat wikiPageUsesTemplate Template:Antiobesity_preparations.
- Cetilistat wikiPageUsesTemplate Template:Cascite.
- Cetilistat wikiPageUsesTemplate Template:Chemspidercite.
- Cetilistat wikiPageUsesTemplate Template:Drugbankcite.
- Cetilistat wikiPageUsesTemplate Template:Drugbox.
- Cetilistat wikiPageUsesTemplate Template:Ebicite.
- Cetilistat wikiPageUsesTemplate Template:Fdacite.
- Cetilistat wikiPageUsesTemplate Template:Keggcite.
- Cetilistat wikiPageUsesTemplate Template:Stdinchicite.
- Cetilistat subject Category:Antiobesity_drugs.
- Cetilistat subject Category:Benzoxazines.
- Cetilistat subject Category:Ethers.
- Cetilistat subject Category:Lactones.
- Cetilistat hypernym Drug.
- Cetilistat type ChemicalSubstance.
- Cetilistat type Drug.
- Cetilistat type Group.
- Cetilistat type Chemical.
- Cetilistat type Drug.
- Cetilistat type Ester.
- Cetilistat type Ether.
- Cetilistat type Group.
- Cetilistat type Heterocycle.
- Cetilistat type Lactone.
- Cetilistat type ChemicalObject.
- Cetilistat type Thing.
- Cetilistat type Q8386.
- Cetilistat comment "Cetilistat is a drug designed to treat obesity. It acts in the same way as the older drug orlistat (Xenical) by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine.".
- Cetilistat label "Cetilistat".
- Cetilistat sameAs Q3010545.
- Cetilistat sameAs Cétilistat.
- Cetilistat sameAs セチリスタット.
- Cetilistat sameAs m.04y8f5r.
- Cetilistat sameAs Cetilistat.
- Cetilistat sameAs Cetilistat.
- Cetilistat sameAs Q3010545.
- Cetilistat sameAs 西替利司他.
- Cetilistat wasDerivedFrom Cetilistat?oldid=701656489.
- Cetilistat depiction Cetilistat.svg.
- Cetilistat isPrimaryTopicOf Cetilistat.