Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Cerivastatin> ?p ?o }
- Cerivastatin abstract "Cerivastatin (brand names: Baycol, Lipobay) is a synthetic member of the class of statins used to lower cholesterol and prevent cardiovascular disease. It was marketed by the pharmaceutical company Bayer A.G. in the late 1990s, competing with Pfizer's highly successful atorvastatin (Lipitor). Cerivastatin was voluntarily withdrawn from the market worldwide in 2001, due to reports of fatal rhabdomyolysis.During postmarketing surveillance, 52 deaths were reported in patients using cerivastatin, mainly from rhabdomyolysis and its resultant renal failure. Risks were higher in patients using fibrates, mainly gemfibrozil (Lopid), and in patients using the highest (0.8 mg/day) dose of cerivastatin. Bayer A.G. added a contraindication for the concomitant use of cerivastatin and gemfibrozil to the package 18 months after the drug interaction was found. The frequency of deadly cases of rhabdomyolysis with cerivastatin was 16 to 80 times higher than with other statins. Another 385 nonfatal cases of rhabdomyolysis were reported. This put the risk of this (rare) complication at 5-10 times that of the other statins. Cerivastatin also induced myopathy in a dose-dependent manner when administered as monotherapy, but that was revealed only after Bayer was sued and unpublished company documents were opened.".
- Cerivastatin atcPrefix "C10".
- Cerivastatin atcSuffix "AA06".
- Cerivastatin casNumber "145599-86-6".
- Cerivastatin chEBI "3558".
- Cerivastatin drugbank "DB00439".
- Cerivastatin fdaUniiCode "AM91H2KS67".
- Cerivastatin iupacName "(3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoic acid".
- Cerivastatin pubchem "446156".
- Cerivastatin thumbnail Cerivastatin2DCSD.svg?width=300.
- Cerivastatin wikiPageID "637177".
- Cerivastatin wikiPageLength "4606".
- Cerivastatin wikiPageOutDegree "24".
- Cerivastatin wikiPageRevisionID "674353364".
- Cerivastatin wikiPageWikiLink Atorvastatin.
- Cerivastatin wikiPageWikiLink Bayer.
- Cerivastatin wikiPageWikiLink Cardiovascular_disease.
- Cerivastatin wikiPageWikiLink Category:Carboxylic_acids.
- Cerivastatin wikiPageWikiLink Category:Diols.
- Cerivastatin wikiPageWikiLink Category:Ethers.
- Cerivastatin wikiPageWikiLink Category:Fluoroarenes.
- Cerivastatin wikiPageWikiLink Category:Pyridines.
- Cerivastatin wikiPageWikiLink Category:Statins.
- Cerivastatin wikiPageWikiLink Category:Withdrawn_drugs.
- Cerivastatin wikiPageWikiLink Cholesterol.
- Cerivastatin wikiPageWikiLink Fibrate.
- Cerivastatin wikiPageWikiLink Gemfibrozil.
- Cerivastatin wikiPageWikiLink Myopathy.
- Cerivastatin wikiPageWikiLink Pfizer.
- Cerivastatin wikiPageWikiLink Pharmaceutical_industry.
- Cerivastatin wikiPageWikiLink Postmarketing_surveillance.
- Cerivastatin wikiPageWikiLink Renal_failure.
- Cerivastatin wikiPageWikiLink Rhabdomyolysis.
- Cerivastatin wikiPageWikiLink Statin.
- Cerivastatin wikiPageWikiLinkText "Cerivastatin".
- Cerivastatin wikiPageWikiLinkText "cerivastatin".
- Cerivastatin atcPrefix "10.0".
- Cerivastatin atcSuffix "AA06".
- Cerivastatin c "26".
- Cerivastatin casNumber "145599".
- Cerivastatin chebi "3558".
- Cerivastatin chembl "1477".
- Cerivastatin chemspiderid "393588".
- Cerivastatin drugbank "DB00439".
- Cerivastatin eliminationHalfLife "-10800.0".
- Cerivastatin f "1".
- Cerivastatin h "34".
- Cerivastatin inchi "1".
- Cerivastatin inchikey "SEERZIQQUAZTOL-ANMDKAQQBT".
- Cerivastatin iupacName "-7".
- Cerivastatin iupharLigand "2950".
- Cerivastatin kegg "D07661".
- Cerivastatin legalStatus "Withdrawn from market".
- Cerivastatin molecularWeight "459.55".
- Cerivastatin n "1".
- Cerivastatin o "5".
- Cerivastatin pregnancyAu "D".
- Cerivastatin pubchem "446156".
- Cerivastatin smiles "O=CC[C@H]C[C@H]/C=C/c1cCC".
- Cerivastatin stdinchi "1".
- Cerivastatin stdinchikey "SEERZIQQUAZTOL-ANMDKAQQSA-N".
- Cerivastatin unii "AM91H2KS67".
- Cerivastatin verifiedfields "changed".
- Cerivastatin verifiedrevid "460025724".
- Cerivastatin width "180".
- Cerivastatin wikiPageUsesTemplate Template:Cascite.
- Cerivastatin wikiPageUsesTemplate Template:Chemspidercite.
- Cerivastatin wikiPageUsesTemplate Template:Drugbankcite.
- Cerivastatin wikiPageUsesTemplate Template:Drugbox.
- Cerivastatin wikiPageUsesTemplate Template:Ebicite.
- Cerivastatin wikiPageUsesTemplate Template:Fdacite.
- Cerivastatin wikiPageUsesTemplate Template:Keggcite.
- Cerivastatin wikiPageUsesTemplate Template:Reflist.
- Cerivastatin wikiPageUsesTemplate Template:Statins.
- Cerivastatin wikiPageUsesTemplate Template:Stdinchicite.
- Cerivastatin subject Category:Carboxylic_acids.
- Cerivastatin subject Category:Diols.
- Cerivastatin subject Category:Ethers.
- Cerivastatin subject Category:Fluoroarenes.
- Cerivastatin subject Category:Pyridines.
- Cerivastatin subject Category:Statins.
- Cerivastatin subject Category:Withdrawn_drugs.
- Cerivastatin hypernym Member.
- Cerivastatin type Agent.
- Cerivastatin type ChemicalSubstance.
- Cerivastatin type Drug.
- Cerivastatin type Group.
- Cerivastatin type Person.
- Cerivastatin type Agent.
- Cerivastatin type Alcohol.
- Cerivastatin type Chemical.
- Cerivastatin type Drug.
- Cerivastatin type Ether.
- Cerivastatin type Group.
- Cerivastatin type Heterocycle.
- Cerivastatin type Inhibitor.
- Cerivastatin type Organofluoride.
- Cerivastatin type Organohalide.
- Cerivastatin type Polyol.
- Cerivastatin type Redirect.