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- Central_spindle abstract "The central spindle is a microtubule based structure, which forms in between segregating chromosomes during anaphase where the two sets of microtubules, emanating from opposite halves of the cell, overlap, and become arranged into antiparallel bundles by various microtubule associated proteins (MAPs) and motor proteins. The central spindle is widely regarded as a key regulating center for cytokinesis, recruiting proteins for successful cleavage furrow positioning and membrane abscission. For these important roles to be achieved successfully the central spindle has to be carefully regulated to control the size of the overlap region, the alignment of those overlaps and the overall length and symmetry of the structure. Without this regulation, signaling faults in cytokinesis can occur, resulting in unequal chromosome segregation or polyploid cells, greatly increasing the risk of cancer.".
- Central_spindle wikiPageID "43939815".
- Central_spindle wikiPageLength "1849".
- Central_spindle wikiPageOutDegree "12".
- Central_spindle wikiPageRevisionID "632048414".
- Central_spindle wikiPageWikiLink Abscission.
- Central_spindle wikiPageWikiLink Anaphase.
- Central_spindle wikiPageWikiLink Cancer.
- Central_spindle wikiPageWikiLink Category:Cell_anatomy.
- Central_spindle wikiPageWikiLink Cell_(biology).
- Central_spindle wikiPageWikiLink Chromosome.
- Central_spindle wikiPageWikiLink Cleavage_furrow.
- Central_spindle wikiPageWikiLink Cytokinesis.
- Central_spindle wikiPageWikiLink Microtubule.
- Central_spindle wikiPageWikiLink Motor_protein.
- Central_spindle wikiPageWikiLink Polyploid.
- Central_spindle wikiPageWikiLinkText "central spindle".
- Central_spindle wikiPageUsesTemplate Template:Reflist.
- Central_spindle subject Category:Cell_anatomy.
- Central_spindle hypernym Microtubule.
- Central_spindle comment "The central spindle is a microtubule based structure, which forms in between segregating chromosomes during anaphase where the two sets of microtubules, emanating from opposite halves of the cell, overlap, and become arranged into antiparallel bundles by various microtubule associated proteins (MAPs) and motor proteins. The central spindle is widely regarded as a key regulating center for cytokinesis, recruiting proteins for successful cleavage furrow positioning and membrane abscission.".
- Central_spindle label "Central spindle".
- Central_spindle sameAs Q18345087.
- Central_spindle sameAs m.011x5d6b.
- Central_spindle sameAs Q18345087.
- Central_spindle wasDerivedFrom Central_spindle?oldid=632048414.
- Central_spindle isPrimaryTopicOf Central_spindle.