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- Cat_genetics abstract "Cat genetics describes the study of inheritance as it occurs in domestic cats. In feline husbandry it can predict established traits (phenotypes) of the offspring of particular crosses. In medical genetics, cat models are occasionally used to discover the function of homologous human disease genes.The domesticated cat and its closest wild ancestor are both diploid organisms that possess 38 chromosomes and roughly 20,000 genes. About 250 heritable genetic disorders have been identified in cats, many similar to human inborn errors. The high level of similarity among the metabolisms of mammals allows many of these feline diseases to be diagnosed using genetic tests that were originally developed for use in humans, as well as the use of cats in the study of the human diseases.An example of a mutation that is shared among all felines, including the big cats, is a mutant chemosensor in their taste buds that prevents them from tasting sweetness, which may explain their indifference to fruits, berries, and other sugary foods. In some breeds of cats congenital deafness is very common, with most white cats (but not albinos) being affected, particularly if they also have blue eyes. The genes responsible for this defect are unknown, but the disease is studied in the hope that it may shed light on the causes of hereditary deafness in humans.Since a large variety of coat patterns exist within the various cat breeds, the cat is an excellent animal to study the coat genetics of hair growth and coloration. Several genes interact to produce cats' hair color and coat patterns. Different combinations of these genes give different phenotypes. For example, the enzyme tyrosinase is needed to produce the dark pigment melanin and Burmese cats have a mutant form that is only active at low temperatures, resulting in color appearing only on the cooler ears, tail and paws. A completely inactive gene for tyrosinase is found in albino cats, which therefore lack all pigment. Hair length is determined by the gene for fibroblast growth factor 5, with inactive copies of this gene causing long hair.The Cat Genome Project, sponsored by the Laboratory of Genomic Diversity at the U.S. National Cancer Institute Frederick Cancer Research and Development Center in Frederick, Maryland, aims to help the development of the cat as an animal model for human hereditary and infectious diseases, as well as contributing to the understanding of the evolution of mammals. This effort led to the publication in 2007 of an initial draft of the genome of an Abyssinian cat called Cinnamon. The existence of a draft genome has led to the discovery of several cat disease genes, and even allowed the development of cat genetic fingerprinting for use in forensics.".
- Cat_genetics thumbnail WhiteCat.jpg?width=300.
- Cat_genetics wikiPageID "14844398".
- Cat_genetics wikiPageLength "8584".
- Cat_genetics wikiPageOutDegree "35".
- Cat_genetics wikiPageRevisionID "656957464".
- Cat_genetics wikiPageWikiLink Abyssinian_cat.
- Cat_genetics wikiPageWikiLink Albinism.
- Cat_genetics wikiPageWikiLink Burmese_cat.
- Cat_genetics wikiPageWikiLink Cat.
- Cat_genetics wikiPageWikiLink Cat_body-type_mutation.
- Cat_genetics wikiPageWikiLink Cat_coat_genetics.
- Cat_genetics wikiPageWikiLink Category:Cat_genetics.
- Cat_genetics wikiPageWikiLink Chemoreceptor.
- Cat_genetics wikiPageWikiLink Chromosome.
- Cat_genetics wikiPageWikiLink DNA_profiling.
- Cat_genetics wikiPageWikiLink Deaf_white_cat.
- Cat_genetics wikiPageWikiLink Enzyme.
- Cat_genetics wikiPageWikiLink FGF5.
- Cat_genetics wikiPageWikiLink Forensic_science.
- Cat_genetics wikiPageWikiLink Frederick,_Maryland.
- Cat_genetics wikiPageWikiLink Gene.
- Cat_genetics wikiPageWikiLink Genetic_disorder.
- Cat_genetics wikiPageWikiLink Genetic_testing.
- Cat_genetics wikiPageWikiLink Hearing_loss.
- Cat_genetics wikiPageWikiLink Inborn_error_of_metabolism.
- Cat_genetics wikiPageWikiLink Infection.
- Cat_genetics wikiPageWikiLink Medical_genetics.
- Cat_genetics wikiPageWikiLink Melanin.
- Cat_genetics wikiPageWikiLink Metabolism.
- Cat_genetics wikiPageWikiLink Model_organism.
- Cat_genetics wikiPageWikiLink Mutation.
- Cat_genetics wikiPageWikiLink National_Cancer_Institute.
- Cat_genetics wikiPageWikiLink Phenotype.
- Cat_genetics wikiPageWikiLink Ploidy.
- Cat_genetics wikiPageWikiLink Taste_bud.
- Cat_genetics wikiPageWikiLink Tyrosinase.
- Cat_genetics wikiPageWikiLink File:WhiteCat.jpg.
- Cat_genetics wikiPageWikiLinkText "Cat genetics".
- Cat_genetics wikiPageUsesTemplate Template:Domestic_cat.
- Cat_genetics wikiPageUsesTemplate Template:Reflist.
- Cat_genetics subject Category:Cat_genetics.
- Cat_genetics comment "Cat genetics describes the study of inheritance as it occurs in domestic cats. In feline husbandry it can predict established traits (phenotypes) of the offspring of particular crosses. In medical genetics, cat models are occasionally used to discover the function of homologous human disease genes.The domesticated cat and its closest wild ancestor are both diploid organisms that possess 38 chromosomes and roughly 20,000 genes.".
- Cat_genetics label "Cat genetics".
- Cat_genetics sameAs Q5051093.
- Cat_genetics sameAs m.03gzwf4.
- Cat_genetics sameAs Q5051093.
- Cat_genetics wasDerivedFrom Cat_genetics?oldid=656957464.
- Cat_genetics depiction WhiteCat.jpg.
- Cat_genetics isPrimaryTopicOf Cat_genetics.