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- Cardiac_Arrhythmia_Suppression_Trial abstract "The Cardiac Arrhythmia Suppression Trial (CAST) was a double-blind, randomized controlled study designed to test the hypothesis that suppression of premature ventricular complexes (PVC) with class I antiarrhythmic agents after a myocardial infarction (MI) would reduce mortality. It was conducted between 1986 and 1989 and included over 1700 patients in 27 centres. The study found that the tested drugs increased mortality instead of lowering it as was expected. The publication of these results in 1991/92, in combination with large follow-up studies for drugs that had not been tested in CAST, led to a paradigm shift in the treatment of MI patients. Class I and III antiarrhythmics are now only used with extreme caution after MI, or they are contraindicated completely. Heart Rhythm Society Distinguished Scientist D. George Wyse was a member of the CAST trial's steering and executive committees.".
- Cardiac_Arrhythmia_Suppression_Trial wikiPageID "33224638".
- Cardiac_Arrhythmia_Suppression_Trial wikiPageLength "6159".
- Cardiac_Arrhythmia_Suppression_Trial wikiPageOutDegree "18".
- Cardiac_Arrhythmia_Suppression_Trial wikiPageRevisionID "700176441".
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink Antiarrhythmic_agent.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink Cardiac_arrhythmia.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink Category:Antiarrhythmic_agents.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink Category:Clinical_trials_related_to_cardiology.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink D._George_Wyse.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink Ejection_fraction.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink Encainide.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink Flecainide.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink Holter_monitor.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink Ischemia.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink Moracizine.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink Mortality_rate.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink Myocardial_infarction.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink National_Heart,_Lung,_and_Blood_Institute.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink Paradigm_shift.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink Premature_ventricular_contraction.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink Randomized_controlled_trial.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLink Sudden_cardiac_death.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLinkText "CAST study".
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLinkText "Cardiac Arrhythmia Suppression Trial (CAST)".
- Cardiac_Arrhythmia_Suppression_Trial wikiPageWikiLinkText "Cardiac Arrhythmia Suppression Trial".
- Cardiac_Arrhythmia_Suppression_Trial wikiPageUsesTemplate Template:ClinicalTrialsGov.
- Cardiac_Arrhythmia_Suppression_Trial wikiPageUsesTemplate Template:Reflist.
- Cardiac_Arrhythmia_Suppression_Trial subject Category:Antiarrhythmic_agents.
- Cardiac_Arrhythmia_Suppression_Trial subject Category:Clinical_trials_related_to_cardiology.
- Cardiac_Arrhythmia_Suppression_Trial hypernym Study.
- Cardiac_Arrhythmia_Suppression_Trial type Agent.
- Cardiac_Arrhythmia_Suppression_Trial type Book.
- Cardiac_Arrhythmia_Suppression_Trial type Drug.
- Cardiac_Arrhythmia_Suppression_Trial type Agent.
- Cardiac_Arrhythmia_Suppression_Trial type Drug.
- Cardiac_Arrhythmia_Suppression_Trial type Trial.
- Cardiac_Arrhythmia_Suppression_Trial comment "The Cardiac Arrhythmia Suppression Trial (CAST) was a double-blind, randomized controlled study designed to test the hypothesis that suppression of premature ventricular complexes (PVC) with class I antiarrhythmic agents after a myocardial infarction (MI) would reduce mortality. It was conducted between 1986 and 1989 and included over 1700 patients in 27 centres. The study found that the tested drugs increased mortality instead of lowering it as was expected.".
- Cardiac_Arrhythmia_Suppression_Trial label "Cardiac Arrhythmia Suppression Trial".
- Cardiac_Arrhythmia_Suppression_Trial sameAs Q1022877.
- Cardiac_Arrhythmia_Suppression_Trial sameAs CAST_(Studie).
- Cardiac_Arrhythmia_Suppression_Trial sameAs m.0h_bbq3.
- Cardiac_Arrhythmia_Suppression_Trial sameAs Q1022877.
- Cardiac_Arrhythmia_Suppression_Trial wasDerivedFrom Cardiac_Arrhythmia_Suppression_Trial?oldid=700176441.
- Cardiac_Arrhythmia_Suppression_Trial isPrimaryTopicOf Cardiac_Arrhythmia_Suppression_Trial.