Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Carcinogen> ?p ?o }
- Carcinogen abstract "A carcinogen is any substance, radionuclide, or radiation that is an agent directly involved in causing cancer. This may be due to the ability to damage the genome or to the disruption of cellular metabolic processes. Several radioactive substances are considered carcinogens, but their carcinogenic activity is attributed to the radiation, for example gamma rays and alpha particles, which they emit. Common examples of non-radioactive carcinogens are inhaled asbestos, certain dioxins, and tobacco smoke. Although the public generally associates carcinogenicity with synthetic chemicals, it is equally likely to arise in both natural and synthetic substances. Carcinogens are not necessarily immediately toxic, thus their effect can be insidious.Cancer is any disease in which normal cells are damaged and do not undergo programmed cell death as fast as they divide via mitosis. Carcinogens may increase the risk of cancer by altering cellular metabolism or damaging DNA directly in cells, which interferes with biological processes, and induces the uncontrolled, malignant division, ultimately leading to the formation of tumors. Usually, severe DNA damage leads to apoptosis, but if the programmed cell death pathway is damaged, then the cell cannot prevent itself from becoming a cancer cell.There are many natural carcinogens. Aflatoxin B1, which is produced by the fungus Aspergillus flavus growing on stored grains, nuts and peanut butter, is an example of a potent, naturally occurring microbial carcinogen. Certain viruses such as hepatitis B and human papilloma virus have been found to cause cancer in humans. The first one shown to cause cancer in animals is Rous sarcoma virus, discovered in 1910 by Peyton Rous. Other infectious organisms which cause cancer in humans include some bacteria (e.g. Helicobacter pylori ) and helminths (e.g. Opisthorchis viverrini and Clonorchis sinensis ).Dioxins and dioxin-like compounds, benzene, kepone, EDB, and asbestos have all been classified as carcinogenic. As far back as the 1930s, industrial smoke and tobacco smoke were identified as sources of dozens of carcinogens, including benzo[a]pyrene, tobacco-specific nitrosamines such as nitrosonornicotine, and reactive aldehydes such as formaldehyde—which is also a hazard in embalming and making plastics. Vinyl chloride, from which PVC is manufactured, is a carcinogen and thus a hazard in PVC production.Co-carcinogens are chemicals that do not necessarily cause cancer on their own, but promote the activity of other carcinogens in causing cancer.After the carcinogen enters the body, the body makes an attempt to eliminate it through a process called biotransformation. The purpose of these reactions is to make the carcinogen more water-soluble so that it can be removed from the body. However, in some cases, these reactions can also convert a less toxic carcinogen into a more toxic carcinogen.DNA is nucleophilic, therefore soluble carbon electrophiles are carcinogenic, because DNA attacks them. For example, some alkenes are toxicated by human enzymes to produce an electrophilic epoxide. DNA attacks the epoxide, and is bound permanently to it. This is the mechanism behind the carcinogenicity of benzo[a]pyrene in tobacco smoke, other aromatics, aflatoxin and mustard gas.".
- Carcinogen thumbnail GHS-pictogram-silhouette.svg?width=300.
- Carcinogen wikiPageExternalLink PED_1_3x_Known_and_Probable_Carcinogens.asp?sitearea=PED.
- Carcinogen wikiPageExternalLink npotocca.html.
- Carcinogen wikiPageExternalLink index.cfm?objectid=03C9B512-ACF8-C1F3-ADBA53CAE848F635.
- Carcinogen wikiPageExternalLink potency.berkeley.edu.
- Carcinogen wikiPageExternalLink MOE.html.
- Carcinogen wikiPageExternalLink chemicals.tcl?short_hazard_name=cancer&all_p=t.
- Carcinogen wikiPageID "6445".
- Carcinogen wikiPageLength "38997".
- Carcinogen wikiPageOutDegree "214".
- Carcinogen wikiPageRevisionID "705239913".
- Carcinogen wikiPageWikiLink 1,2-Dibromoethane.
- Carcinogen wikiPageWikiLink Acrylamide.
- Carcinogen wikiPageWikiLink Aflatoxin.
- Carcinogen wikiPageWikiLink Alcohol.
- Carcinogen wikiPageWikiLink Aldehyde.
- Carcinogen wikiPageWikiLink Alkene.
- Carcinogen wikiPageWikiLink Alkylating_antineoplastic_agent.
- Carcinogen wikiPageWikiLink Alkylation.
- Carcinogen wikiPageWikiLink Alpha_particle.
- Carcinogen wikiPageWikiLink American_Conference_of_Governmental_Industrial_Hygienists.
- Carcinogen wikiPageWikiLink Apoptosis.
- Carcinogen wikiPageWikiLink Arsenic.
- Carcinogen wikiPageWikiLink Asbestos.
- Carcinogen wikiPageWikiLink Asbestosis.
- Carcinogen wikiPageWikiLink Asian_Dust.
- Carcinogen wikiPageWikiLink Aspergillus_flavus.
- Carcinogen wikiPageWikiLink Bacteria.
- Carcinogen wikiPageWikiLink Barbecue.
- Carcinogen wikiPageWikiLink Benzene.
- Carcinogen wikiPageWikiLink Benzo(a)pyrene.
- Carcinogen wikiPageWikiLink Beryllium.
- Carcinogen wikiPageWikiLink Beta_particle.
- Carcinogen wikiPageWikiLink Biology.
- Carcinogen wikiPageWikiLink Biotransformation.
- Carcinogen wikiPageWikiLink Bladder_cancer.
- Carcinogen wikiPageWikiLink Bone_seeker.
- Carcinogen wikiPageWikiLink Bone_tumor.
- Carcinogen wikiPageWikiLink Breast_cancer.
- Carcinogen wikiPageWikiLink Cadmium.
- Carcinogen wikiPageWikiLink Cancer.
- Carcinogen wikiPageWikiLink Carbohydrate.
- Carcinogen wikiPageWikiLink Carcinogen.
- Carcinogen wikiPageWikiLink Carcinogenesis.
- Carcinogen wikiPageWikiLink Category:Carcinogenesis.
- Carcinogen wikiPageWikiLink Category:Carcinogens.
- Carcinogen wikiPageWikiLink Category:Radiation_health_effects.
- Carcinogen wikiPageWikiLink Cell_(biology).
- Carcinogen wikiPageWikiLink Cereal.
- Carcinogen wikiPageWikiLink Charring.
- Carcinogen wikiPageWikiLink Chlormethine.
- Carcinogen wikiPageWikiLink Chromium.
- Carcinogen wikiPageWikiLink Circadian_rhythm.
- Carcinogen wikiPageWikiLink Clonorchis_sinensis.
- Carcinogen wikiPageWikiLink Co-carcinogen.
- Carcinogen wikiPageWikiLink Coke_(fuel).
- Carcinogen wikiPageWikiLink Colorectal_cancer.
- Carcinogen wikiPageWikiLink DNA.
- Carcinogen wikiPageWikiLink Dangerous_Preparations_Directive.
- Carcinogen wikiPageWikiLink EEC).
- Carcinogen wikiPageWikiLink Detergent.
- Carcinogen wikiPageWikiLink Diesel_exhaust.
- Carcinogen wikiPageWikiLink Dimethyl_sulfate.
- Carcinogen wikiPageWikiLink Dioxins_and_dioxin-like_compounds.
- Carcinogen wikiPageWikiLink Electromagnetic_radiation_and_health.
- Carcinogen wikiPageWikiLink Electromagnetic_spectrum.
- Carcinogen wikiPageWikiLink Electrophile.
- Carcinogen wikiPageWikiLink Embalming.
- Carcinogen wikiPageWikiLink Enzyme.
- Carcinogen wikiPageWikiLink Epoxide.
- Carcinogen wikiPageWikiLink Ethylene_oxide.
- Carcinogen wikiPageWikiLink Europe.
- Carcinogen wikiPageWikiLink Exhaust_gas.
- Carcinogen wikiPageWikiLink Food_Standards_Agency.
- Carcinogen wikiPageWikiLink Food_and_Drug_Administration.
- Carcinogen wikiPageWikiLink Food_irradiation.
- Carcinogen wikiPageWikiLink Formaldehyde.
- Carcinogen wikiPageWikiLink France.
- Carcinogen wikiPageWikiLink Francis_Peyton_Rous.
- Carcinogen wikiPageWikiLink French_fries.
- Carcinogen wikiPageWikiLink Fuel_oil.
- Carcinogen wikiPageWikiLink Fumigation.
- Carcinogen wikiPageWikiLink Fungus.
- Carcinogen wikiPageWikiLink Gamma_ray.
- Carcinogen wikiPageWikiLink Gasoline.
- Carcinogen wikiPageWikiLink Gastrointestinal_cancer.
- Carcinogen wikiPageWikiLink Genome.
- Carcinogen wikiPageWikiLink Genotoxicity.
- Carcinogen wikiPageWikiLink Globally_Harmonized_System_of_Classification_and_Labelling_of_Chemicals.
- Carcinogen wikiPageWikiLink Grilling.
- Carcinogen wikiPageWikiLink Helicobacter_pylori.
- Carcinogen wikiPageWikiLink Helminths.
- Carcinogen wikiPageWikiLink Hemangiosarcoma.
- Carcinogen wikiPageWikiLink Hepatitis_B.
- Carcinogen wikiPageWikiLink History_of_cancer.
- Carcinogen wikiPageWikiLink Hodgkins_lymphoma.
- Carcinogen wikiPageWikiLink Human_papillomavirus.
- Carcinogen wikiPageWikiLink Industrial_Union_Department_v._American_Petroleum_Institute.
- Carcinogen wikiPageWikiLink Industry.