Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Captodiame> ?p ?o }
- Captodiame abstract "Captodiame (INN), also known as captodiamine, is an antihistamine sold under the trade names Covatine, Covatix, and Suvren which is used as a sedative and anxiolytic. It is a derivative of diphenhydramine.A 2004 study suggested captodiame may be helpful in preventing benzodiazepine withdrawal syndrome in people discontinuing benzodiazepine treatment.In addition to its actions as an antihistamine, captodiamine has been found to act as a 5-HT2C receptor antagonist and σ1 receptor and D3 receptor agonist. It produces antidepressant-like effects in rats. However, captodiamine is unique among antidepressant-like drugs in that it increases brain-derived neurotrophic factor (BDNF) levels in the hypothalamus but not in the frontal cortex or hippocampus. This unique action may be related to its ability to attenuate stress-induced anhedonia and corticotropin-releasing factor (CRF) signaling in the hypothalamus.".
- Captodiame atcPrefix "N05".
- Captodiame atcSuffix "BB02".
- Captodiame casNumber "486-17-9".
- Captodiame drugbank "DB09014".
- Captodiame fdaUniiCode "H93K9455DD".
- Captodiame iupacName "2-[(4-butylsulfanylphenyl)-phenyl-methyl]sulfanyl-N,N-dimethylethanamine".
- Captodiame pubchem "10240".
- Captodiame thumbnail Captodiame.svg?width=300.
- Captodiame wikiPageID "12718693".
- Captodiame wikiPageLength "4894".
- Captodiame wikiPageOutDegree "38".
- Captodiame wikiPageRevisionID "703427104".
- Captodiame wikiPageWikiLink 5-HT2C_receptor.
- Captodiame wikiPageWikiLink Agonist.
- Captodiame wikiPageWikiLink Anhedonia.
- Captodiame wikiPageWikiLink Antidepressant.
- Captodiame wikiPageWikiLink Antihistamine.
- Captodiame wikiPageWikiLink Anxiolytic.
- Captodiame wikiPageWikiLink Benzodiazepine.
- Captodiame wikiPageWikiLink Benzodiazepine_withdrawal_syndrome.
- Captodiame wikiPageWikiLink Benzophenone.
- Captodiame wikiPageWikiLink Benzoyl_chloride.
- Captodiame wikiPageWikiLink Brain-derived_neurotrophic_factor.
- Captodiame wikiPageWikiLink Category:5-HT2C_antagonists.
- Captodiame wikiPageWikiLink Category:Anticholinergics.
- Captodiame wikiPageWikiLink Category:Antihistamines.
- Captodiame wikiPageWikiLink Category:Anxiolytics.
- Captodiame wikiPageWikiLink Category:Dopamine_agonists.
- Captodiame wikiPageWikiLink Category:Sedatives.
- Captodiame wikiPageWikiLink Category:Sigma_agonists.
- Captodiame wikiPageWikiLink Category:Thioethers.
- Captodiame wikiPageWikiLink Corticotropin-releasing_factor_family.
- Captodiame wikiPageWikiLink Cyproheptadine.
- Captodiame wikiPageWikiLink Derivative_(chemistry).
- Captodiame wikiPageWikiLink Diphenhydramine.
- Captodiame wikiPageWikiLink Dopamine_receptor_D3.
- Captodiame wikiPageWikiLink Friedel–Crafts_reaction.
- Captodiame wikiPageWikiLink Frontal_lobe.
- Captodiame wikiPageWikiLink Hippocampus.
- Captodiame wikiPageWikiLink Hydroxyzine.
- Captodiame wikiPageWikiLink Hypothalamus.
- Captodiame wikiPageWikiLink International_nonproprietary_name.
- Captodiame wikiPageWikiLink Isothiouronium.
- Captodiame wikiPageWikiLink Kidney.
- Captodiame wikiPageWikiLink Receptor_antagonist.
- Captodiame wikiPageWikiLink Sedative.
- Captodiame wikiPageWikiLink Sigma-1_receptor.
- Captodiame wikiPageWikiLink Stress_(psychological).
- Captodiame wikiPageWikiLink Thiourea.
- Captodiame wikiPageWikiLink File:Captodiamine_synthesis.png.
- Captodiame wikiPageWikiLinkText "Captodiame".
- Captodiame wikiPageWikiLinkText "captodiame".
- Captodiame atcPrefix "N05".
- Captodiame atcSuffix "BB02".
- Captodiame c "21".
- Captodiame casNumber "486".
- Captodiame chemspiderid "9823".
- Captodiame drugbank "DB09014".
- Captodiame excretion Kidney.
- Captodiame h "29".
- Captodiame inchi "1".
- Captodiame inchikey "IZLPZXSZLLELBJ-UHFFFAOYAE".
- Captodiame iupacName "2".
- Captodiame kegg "D07316".
- Captodiame legalStatus "Rx-only".
- Captodiame molecularWeight "359.594".
- Captodiame n "1".
- Captodiame pubchem "10240".
- Captodiame routesOfAdministration "Oral".
- Captodiame s "2".
- Captodiame smiles "SCCCC".
- Captodiame stdinchi "1".
- Captodiame stdinchikey "IZLPZXSZLLELBJ-UHFFFAOYSA-N".
- Captodiame unii "H93K9455DD".
- Captodiame verifiedfields "changed".
- Captodiame verifiedrevid "447821290".
- Captodiame wikiPageUsesTemplate Template:Anxiolytics.
- Captodiame wikiPageUsesTemplate Template:Cascite.
- Captodiame wikiPageUsesTemplate Template:Chemspidercite.
- Captodiame wikiPageUsesTemplate Template:Cholinergics.
- Captodiame wikiPageUsesTemplate Template:Dopaminergics.
- Captodiame wikiPageUsesTemplate Template:Drugbankcite.
- Captodiame wikiPageUsesTemplate Template:Drugbox.
- Captodiame wikiPageUsesTemplate Template:Drugs.com.
- Captodiame wikiPageUsesTemplate Template:Fdacite.
- Captodiame wikiPageUsesTemplate Template:Histaminergics.
- Captodiame wikiPageUsesTemplate Template:Keggcite.
- Captodiame wikiPageUsesTemplate Template:Reflist.
- Captodiame wikiPageUsesTemplate Template:Sedatives.
- Captodiame wikiPageUsesTemplate Template:Serotonergics.
- Captodiame wikiPageUsesTemplate Template:Sigmaergics.
- Captodiame wikiPageUsesTemplate Template:Stdinchicite.
- Captodiame wikiPageUsesTemplate Template:US_patent.
- Captodiame subject Category:5-HT2C_antagonists.
- Captodiame subject Category:Anticholinergics.
- Captodiame subject Category:Antihistamines.
- Captodiame subject Category:Anxiolytics.
- Captodiame subject Category:Dopamine_agonists.
- Captodiame subject Category:Sedatives.