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- Candoxatril abstract "Candoxatril is the orally active prodrug of candoxatrilat (UK-73967) human neutral endopeptidase (Neprilysin) as the neutral endopeptidase 24.11 complexed (RB-101) with phosphoramidon degrades and inactivates a number of bioactive peptides. Two multiply connected folding domains of the neutral endopeptidase locus splicing of exons 1, 2a, or 2b to the common exon 3 composed of 24 exons of the human CALLA/NEP gene containing the active site, it is known as peptidase family M13 (neprilysin family, clan MA(E)) the gluzincins a faint but significant structural relationship of the metzincins to the thermolysin-like enzymes, Zincin is the simplest descriptor of biological space. The structure reveals two multiply connected folding domains which embrace a large central cavity containing the active site of the 5-indanyl ester prodrug candoxatril and differs from phosphoramidon [N-(N-(((6-Deoxy-α-L-mannopyranosyl)oxy)hydroxyphosphinyl)-L- leucyl)-L-tryptophan] in several respects the structure of human neutral endopeptidase complexed with phosphoramidon is lost due to desolvation of the enzyme and ligand on formation of the complex Candoxatril.".
- Candoxatril iupacName "4-{[(1-{3-(2,3-dihydro-1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl}cyclopentyl)carbonyl]amino}cyclohexanecarboxylic acid".
- Candoxatril thumbnail Candoxatril.png?width=300.
- Candoxatril wikiPageID "29418677".
- Candoxatril wikiPageLength "8693".
- Candoxatril wikiPageOutDegree "12".
- Candoxatril wikiPageRevisionID "707257985".
- Candoxatril wikiPageWikiLink Category:Carboxamides.
- Candoxatril wikiPageWikiLink Category:Carboxylate_esters.
- Candoxatril wikiPageWikiLink Category:Carboxylic_acids.
- Candoxatril wikiPageWikiLink Category:Drugs_acting_on_the_gastrointestinal_system_and_metabolism.
- Candoxatril wikiPageWikiLink Category:Ethers.
- Candoxatril wikiPageWikiLink Category:Indanes.
- Candoxatril wikiPageWikiLink Ecadotril.
- Candoxatril wikiPageWikiLink Neprilysin.
- Candoxatril wikiPageWikiLink Phosphoramidon.
- Candoxatril wikiPageWikiLink RB-101.
- Candoxatril wikiPageWikiLink Thermolysin.
- Candoxatril wikiPageWikiLinkText "Candoxatril".
- Candoxatril wikiPageWikiLinkText "candoxatril".
- Candoxatril imagefile "Candoxatril.png".
- Candoxatril iupacname "4".
- Candoxatril wikiPageUsesTemplate Template:Chembox.
- Candoxatril wikiPageUsesTemplate Template:Chembox_Hazards.
- Candoxatril wikiPageUsesTemplate Template:Chembox_Identifiers.
- Candoxatril wikiPageUsesTemplate Template:Chembox_Properties.
- Candoxatril wikiPageUsesTemplate Template:Fdacite.
- Candoxatril wikiPageUsesTemplate Template:Opioidergics.
- Candoxatril wikiPageUsesTemplate Template:Reflist.
- Candoxatril subject Category:Carboxamides.
- Candoxatril subject Category:Carboxylate_esters.
- Candoxatril subject Category:Carboxylic_acids.
- Candoxatril subject Category:Drugs_acting_on_the_gastrointestinal_system_and_metabolism.
- Candoxatril subject Category:Ethers.
- Candoxatril subject Category:Indanes.
- Candoxatril type ChemicalCompound.
- Candoxatril type ChemicalSubstance.
- Candoxatril type Drug.
- Candoxatril type Group.
- Candoxatril type Amide.
- Candoxatril type Drug.
- Candoxatril type Ester.
- Candoxatril type Ether.
- Candoxatril type Group.
- Candoxatril type Hydrocarbon.
- Candoxatril type Redirect.
- Candoxatril type ChemicalObject.
- Candoxatril type Thing.
- Candoxatril type Q11173.
- Candoxatril comment "Candoxatril is the orally active prodrug of candoxatrilat (UK-73967) human neutral endopeptidase (Neprilysin) as the neutral endopeptidase 24.11 complexed (RB-101) with phosphoramidon degrades and inactivates a number of bioactive peptides.".
- Candoxatril label "Candoxatril".
- Candoxatril sameAs Q5032033.
- Candoxatril sameAs m.0dsc7bn.
- Candoxatril sameAs Kandoksatril.
- Candoxatril sameAs Kandoksatril.
- Candoxatril sameAs Q5032033.
- Candoxatril wasDerivedFrom Candoxatril?oldid=707257985.
- Candoxatril depiction Candoxatril.png.
- Candoxatril isPrimaryTopicOf Candoxatril.