Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Camptothecin> ?p ?o }
- Camptothecin abstract "Camptothecin (CPT) is a cytotoxic quinoline alkaloid which inhibits the DNA enzyme topoisomerase I (topo I). It was discovered in 1966 by M. E. Wall and M. C. Wani in systematic screening of natural products for anticancer drugs. It was isolated from the bark and stem of Camptotheca acuminata (Camptotheca, Happy tree), a tree native to China used as a cancer treatment in Traditional Chinese Medicine. CPT showed remarkable anticancer activity in preliminary clinical trials but also low solubility and (high) adverse drug reaction. Because of these disadvantages synthetic and medicinal chemists have developed numerous syntheses of Camptothecin and various derivatives to increase the benefits of the chemical, with good results. Two CPT analogues have been approved and are used in cancer chemotherapy today, topotecan and irinotecan.".
- Camptothecin atcPrefix "none".
- Camptothecin casNumber "7689-03-4".
- Camptothecin chEBI "27656".
- Camptothecin drugbank "DB04690".
- Camptothecin fdaUniiCode "XT3Z54Z28A".
- Camptothecin iupacName "(S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]".
- Camptothecin iupacName "quinoline-3,14-(4H,12H)-dione".
- Camptothecin pubchem "2538".
- Camptothecin thumbnail Camptothecin.svg?width=300.
- Camptothecin wikiPageID "14127651".
- Camptothecin wikiPageLength "18533".
- Camptothecin wikiPageOutDegree "99".
- Camptothecin wikiPageRevisionID "708053355".
- Camptothecin wikiPageWikiLink Adverse_drug_reaction.
- Camptothecin wikiPageWikiLink Alkaloid.
- Camptothecin wikiPageWikiLink Alkyl.
- Camptothecin wikiPageWikiLink Alpha_and_beta_carbon.
- Camptothecin wikiPageWikiLink Amine.
- Camptothecin wikiPageWikiLink Apoptosis.
- Camptothecin wikiPageWikiLink Arginine.
- Camptothecin wikiPageWikiLink Aspartic_acid.
- Camptothecin wikiPageWikiLink BNP_1350.
- Camptothecin wikiPageWikiLink Bark.
- Camptothecin wikiPageWikiLink Blood_plasma.
- Camptothecin wikiPageWikiLink Blood–brain_barrier.
- Camptothecin wikiPageWikiLink Bromine.
- Camptothecin wikiPageWikiLink CKD_602.
- Camptothecin wikiPageWikiLink CRLX101.
- Camptothecin wikiPageWikiLink Camptotheca.
- Camptothecin wikiPageWikiLink Cancer.
- Camptothecin wikiPageWikiLink Carbon.
- Camptothecin wikiPageWikiLink Carbonyl.
- Camptothecin wikiPageWikiLink Category:Alcohols.
- Camptothecin wikiPageWikiLink Category:Alkaloids.
- Camptothecin wikiPageWikiLink Category:Lactams.
- Camptothecin wikiPageWikiLink Category:Lactones.
- Camptothecin wikiPageWikiLink Category:Pyranoindolizinoquinolines.
- Camptothecin wikiPageWikiLink Category:Topoisomerase_inhibitors.
- Camptothecin wikiPageWikiLink Cell_(biology).
- Camptothecin wikiPageWikiLink Chemical_compound.
- Camptothecin wikiPageWikiLink Chemical_equilibrium.
- Camptothecin wikiPageWikiLink Chemical_substance.
- Camptothecin wikiPageWikiLink Chemotherapy.
- Camptothecin wikiPageWikiLink China.
- Camptothecin wikiPageWikiLink Chirality_(chemistry).
- Camptothecin wikiPageWikiLink Chlorine.
- Camptothecin wikiPageWikiLink Clinical_trial.
- Camptothecin wikiPageWikiLink Conjugated_system.
- Camptothecin wikiPageWikiLink Cyclodextrin.
- Camptothecin wikiPageWikiLink Cytosine.
- Camptothecin wikiPageWikiLink Cytotoxicity.
- Camptothecin wikiPageWikiLink DB_67_(AR67).
- Camptothecin wikiPageWikiLink DNA.
- Camptothecin wikiPageWikiLink Drug.
- Camptothecin wikiPageWikiLink Drug_resistance.
- Camptothecin wikiPageWikiLink Enzyme.
- Camptothecin wikiPageWikiLink Enzyme_inhibitor.
- Camptothecin wikiPageWikiLink Ethyl_group.
- Camptothecin wikiPageWikiLink Exatecan.
- Camptothecin wikiPageWikiLink Hydrogen_bond.
- Camptothecin wikiPageWikiLink Hydrolysis.
- Camptothecin wikiPageWikiLink Hydrophile.
- Camptothecin wikiPageWikiLink Hydroxyl.
- Camptothecin wikiPageWikiLink Inductive_effect.
- Camptothecin wikiPageWikiLink Interaction.
- Camptothecin wikiPageWikiLink Intracellular.
- Camptothecin wikiPageWikiLink Irinotecan.
- Camptothecin wikiPageWikiLink Irreversible_process.
- Camptothecin wikiPageWikiLink Lactone.
- Camptothecin wikiPageWikiLink Lipophilicity.
- Camptothecin wikiPageWikiLink Lurtotecan.
- Camptothecin wikiPageWikiLink Methoxy.
- Camptothecin wikiPageWikiLink Methylene_bridge.
- Camptothecin wikiPageWikiLink Methylenedioxy.
- Camptothecin wikiPageWikiLink Molecular_configuration.
- Camptothecin wikiPageWikiLink Natural_product.
- Camptothecin wikiPageWikiLink Neoplasm.
- Camptothecin wikiPageWikiLink Nitro_compound.
- Camptothecin wikiPageWikiLink Nitrogen.
- Camptothecin wikiPageWikiLink Passive_transport.
- Camptothecin wikiPageWikiLink Peptide_sequence.
- Camptothecin wikiPageWikiLink Physical_property.
- Camptothecin wikiPageWikiLink Plant_stem.
- Camptothecin wikiPageWikiLink Polarizability.
- Camptothecin wikiPageWikiLink Protein.
- Camptothecin wikiPageWikiLink Pyridone.
- Camptothecin wikiPageWikiLink Pyrimidine.
- Camptothecin wikiPageWikiLink Pyrrole.
- Camptothecin wikiPageWikiLink Quinoline.
- Camptothecin wikiPageWikiLink Red_blood_cell.
- Camptothecin wikiPageWikiLink ST_1481.
- Camptothecin wikiPageWikiLink Solubility.
- Camptothecin wikiPageWikiLink Structural_analog.
- Camptothecin wikiPageWikiLink Structure.
- Camptothecin wikiPageWikiLink Substitution_reaction.
- Camptothecin wikiPageWikiLink Topotecan.
- Camptothecin wikiPageWikiLink Traditional_Chinese_medicine.
- Camptothecin wikiPageWikiLink Tree.
- Camptothecin wikiPageWikiLink Type_I_topoisomerase.