Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/CKMT2> ?p ?o }
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- CKMT2 abstract "Creatine kinase S-type, mitochondrial is an enzyme that in humans is encoded by the CKMT2 gene.Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. The \"energy-rich\" gamma-phosphate group of ATP that is generated by oxidative phosphorylation inside mitochondria is trans-phosphorylated to creatine (Cr) to give phospho-creatine (PCr), which then is exported from the mitochondria into the cytosol, where it is made available to cytosolic creatine kinases (CK) for in situ regeneration of the ATP that has been used for cellular work. Cr then is returning to the mitochondria where it stimulates mitochondrial respiration and again is charged-up by mitochondrial ATP via MtCK. This process is termed the PCr/Cr-shuttle or circuit. MtCK belongs to the creatine kinase (CK) isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis.".
- CKMT2 entrezgene "1160".
- CKMT2 wikiPageID "14772952".
- CKMT2 wikiPageLength "10087".
- CKMT2 wikiPageOutDegree "13".
- CKMT2 wikiPageRevisionID "673171856".
- CKMT2 wikiPageWikiLink Adenosine_triphosphate.
- CKMT2 wikiPageWikiLink Creatine.
- CKMT2 wikiPageWikiLink Creatine_kinase.
- CKMT2 wikiPageWikiLink Creatine_phosphate_shuttle.
- CKMT2 wikiPageWikiLink Cytosol.
- CKMT2 wikiPageWikiLink Dimer_(chemistry).
- CKMT2 wikiPageWikiLink Enzyme.
- CKMT2 wikiPageWikiLink Gene.
- CKMT2 wikiPageWikiLink Homology_(biology).
- CKMT2 wikiPageWikiLink Isozyme.
- CKMT2 wikiPageWikiLink Mitochondrion.
- CKMT2 wikiPageWikiLink Octamers.
- CKMT2 wikiPageWikiLink Oxidative_phosphorylation.
- CKMT2 wikiPageWikiLinkText "CKMT2".
- CKMT2 requireManualInspection "no".
- CKMT2 summaryText "Mitochondrial creatine kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. The "energy-rich" gamma-phosphate group of ATP that is generated by oxidative phosphorylation inside mitochondria is trans-phosphorylated to creatine to give phospho-creatine , which then is exported from the mitochondria into the cytosol, where it is made available to cytosolic creatine kinases for in situ regeneration of the ATP that has been used for cellular work. Cr then is returning to the mitochondria where it stimulates mitochondrial respiration and again is charged-up by mitochondrial ATP via MtCK. This process is termed the PCr/Cr-shuttle or circuit. MtCK belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis.".
- CKMT2 updateCitations "yes".
- CKMT2 updatePage "yes".
- CKMT2 updateProteinBox "yes".
- CKMT2 updateSummary "yes".
- CKMT2 wikiPageUsesTemplate Template:Cite_journal.
- CKMT2 wikiPageUsesTemplate Template:Gene-5-stub.
- CKMT2 wikiPageUsesTemplate Template:PBB.
- CKMT2 wikiPageUsesTemplate Template:PBB_Controls.
- CKMT2 wikiPageUsesTemplate Template:PBB_Further_reading.
- CKMT2 wikiPageUsesTemplate Template:PBB_Summary.
- CKMT2 wikiPageUsesTemplate Template:PDB_Gallery.
- CKMT2 wikiPageUsesTemplate Template:Refbegin.
- CKMT2 wikiPageUsesTemplate Template:Refend.
- CKMT2 wikiPageUsesTemplate Template:Reflist.
- CKMT2 hypernym Enzyme.
- CKMT2 type Biomolecule.
- CKMT2 type Protein.
- CKMT2 type Thing.
- CKMT2 type Q206229.
- CKMT2 type Q8054.
- CKMT2 comment "Creatine kinase S-type, mitochondrial is an enzyme that in humans is encoded by the CKMT2 gene.Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine.".
- CKMT2 label "CKMT2".
- CKMT2 sameAs Q17862004.
- CKMT2 sameAs m.03gxh_v.
- CKMT2 sameAs Q17862004.
- CKMT2 wasDerivedFrom CKMT2?oldid=673171856.
- CKMT2 isPrimaryTopicOf CKMT2.