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- CCL8 abstract "Chemokine (C-C motif) ligand 8, also known as monocyte chemoattractant protein 2 (MCP-2), is a protein that in humans is encoded by the CCL8 gene.CCL8 is a small cytokine belonging to the CC chemokine family. The CCL8 protein is produced as a precursor containing 109 amino acids, which is cleaved to produce mature CCL8 containing 75 amino acids. The gene for CCL8 is encoded by 3 exons and is located within a large cluster of CC chemokines on chromosome 17q11.2 in humans. MCP-2 is chemotactic for and activates a many different immune cells, including mast cells, eosinophils and basophils, (that are implicated in allergic responses), and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors called chemokine receptors. These receptors include CCR1, CCR2B and CCR5.Monocyte chemotactic protein 2 (MCP-2) is a CC chemokine that utilizes multiple cellular receptors to attract and activate human leukocytes. MCP-2 is a potent inhibitor of HIV-1 by virtue of its high-affinity binding to the receptor CCR5, one of the major co-receptors for HIV-1.".
- CCL8 entrezgene "6355".
- CCL8 wikiPageID "8461487".
- CCL8 wikiPageLength "9683".
- CCL8 wikiPageOutDegree "23".
- CCL8 wikiPageRevisionID "659855288".
- CCL8 wikiPageWikiLink Allergy.
- CCL8 wikiPageWikiLink Amino_acid.
- CCL8 wikiPageWikiLink Basophil_granulocyte.
- CCL8 wikiPageWikiLink CC_chemokine_receptors.
- CCL8 wikiPageWikiLink Category:Cytokines.
- CCL8 wikiPageWikiLink Chemokine.
- CCL8 wikiPageWikiLink Chemokine_receptor.
- CCL8 wikiPageWikiLink Chemotaxis.
- CCL8 wikiPageWikiLink Chromosome_17_(human).
- CCL8 wikiPageWikiLink Cytokine.
- CCL8 wikiPageWikiLink Eosinophil_granulocyte.
- CCL8 wikiPageWikiLink Exon.
- CCL8 wikiPageWikiLink Gene.
- CCL8 wikiPageWikiLink Inflammation.
- CCL8 wikiPageWikiLink Mast_cell.
- CCL8 wikiPageWikiLink Monocyte.
- CCL8 wikiPageWikiLink Natural_killer_cell.
- CCL8 wikiPageWikiLink Protein.
- CCL8 wikiPageWikiLink Protein_precursor.
- CCL8 wikiPageWikiLink T_cell.
- CCL8 wikiPageWikiLinkText "CCL8".
- CCL8 wikiPageUsesTemplate Template:Chemokines.
- CCL8 wikiPageUsesTemplate Template:Cite_journal.
- CCL8 wikiPageUsesTemplate Template:Gene-17-stub.
- CCL8 wikiPageUsesTemplate Template:PBB.
- CCL8 wikiPageUsesTemplate Template:PDB_Gallery.
- CCL8 wikiPageUsesTemplate Template:Refbegin.
- CCL8 wikiPageUsesTemplate Template:Refend.
- CCL8 wikiPageUsesTemplate Template:Reflist.
- CCL8 subject Category:Cytokines.
- CCL8 hypernym Protein.
- CCL8 type Biomolecule.
- CCL8 type Protein.
- CCL8 type Thing.
- CCL8 type Q206229.
- CCL8 type Q8054.
- CCL8 comment "Chemokine (C-C motif) ligand 8, also known as monocyte chemoattractant protein 2 (MCP-2), is a protein that in humans is encoded by the CCL8 gene.CCL8 is a small cytokine belonging to the CC chemokine family. The CCL8 protein is produced as a precursor containing 109 amino acids, which is cleaved to produce mature CCL8 containing 75 amino acids. The gene for CCL8 is encoded by 3 exons and is located within a large cluster of CC chemokines on chromosome 17q11.2 in humans.".
- CCL8 label "CCL8".
- CCL8 sameAs Q14907647.
- CCL8 sameAs CCL8.
- CCL8 sameAs m.02748nb.
- CCL8 sameAs CCL8.
- CCL8 sameAs CCL8.
- CCL8 sameAs Q14907647.
- CCL8 wasDerivedFrom CCL8?oldid=659855288.
- CCL8 isPrimaryTopicOf CCL8.