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- Brome_mosaic_virus abstract "Brome mosaic virus (BMV) is a small (28 nm, 86S), positive-stranded, icosahedral RNA plant virus belonging to the genus Bromovirus, family Bromoviridae, in the alphavirus-like superfamily.BMV commonly infects Bromus inermis (see Bromus) and other grasses, can be found almost anywhere wheat is grown, and thrives in areas with heavy foot or machinery traffic. It is also one of the few grass viruses that infects dicotyledonous plants; however, it primarily infects monocotyledonous plants, such as barley and others in the family Gramineae.BMV was first isolated in 1942 from bromegrass (Bromus inermis), had its genomic organization determined by the 1970s, and was completely sequenced with commercially available clones by the 1980s.The alphavirus-like superfamily includes more than 250 plant and animal viruses including Tobacco mosaic virus, Semliki forest virus, Hepatitis E virus, Sindbis virus, and arboviruses (which cause certain types of encephalitis). Many of the positive-strand RNA viruses that belong to the alphavirus family share a high degree of similarity in proteins involved in genomic replication and synthesis. The sequence similarities of RNA replication genes and strategies for BMV have been shown to extend to a wide range of plant and animal viruses beyond the alphaviruses, including many other positive-strand RNA viruses from other families. Understanding how these viruses replicate and targeting key points in their life cycle can help advance antiviral treatments worldwide.BMV has a genome that is divided into three 5' capped RNAs. RNA1 (3.2 kb) encodes a protein called 1a (109 kDa), which contains both an N-proximal methyltransferase domain and a C-proximal helicase-like domain. The methyltransferase domain shows sequence similarity to other alphavirus m7G methyltransferases and guanyltransferases, called nsP1 proteins, involved in RNA capping. RNA2 (2.9 kb) encodes the 2a protein (94 kDa), the RNA-dependent RNA polymerase, responsible for replication of the viral genome. The dicistronic RNA3 (2.1 kb) encodes for two proteins, the 3a protein (involved in cell-to-cell migration during infection) and the coat protein (for RNA encapsidation and vascular spread), which is expressed from a subgenomic replication intermediate mRNA, called RNA4 (0.9 kb). 3a and coat protein are essential for systemic infection in plants but not RNA replication.".
- Brome_mosaic_virus family Bromoviridae.
- Brome_mosaic_virus genus Bromovirus.
- Brome_mosaic_virus thumbnail Image1js9.png?width=300.
- Brome_mosaic_virus wikiPageID "1640923".
- Brome_mosaic_virus wikiPageLength "6737".
- Brome_mosaic_virus wikiPageOutDegree "30".
- Brome_mosaic_virus wikiPageRevisionID "701953170".
- Brome_mosaic_virus wikiPageWikiLink Alphavirus.
- Brome_mosaic_virus wikiPageWikiLink Arbovirus.
- Brome_mosaic_virus wikiPageWikiLink Bromoviridae.
- Brome_mosaic_virus wikiPageWikiLink Bromovirus.
- Brome_mosaic_virus wikiPageWikiLink Bromus.
- Brome_mosaic_virus wikiPageWikiLink Bromus_inermis.
- Brome_mosaic_virus wikiPageWikiLink Category:Bromoviridae.
- Brome_mosaic_virus wikiPageWikiLink Category:Viral_plant_pathogens_and_diseases.
- Brome_mosaic_virus wikiPageWikiLink Cloning.
- Brome_mosaic_virus wikiPageWikiLink Dicotyledon.
- Brome_mosaic_virus wikiPageWikiLink Encephalitis.
- Brome_mosaic_virus wikiPageWikiLink Five-prime_cap.
- Brome_mosaic_virus wikiPageWikiLink Gene.
- Brome_mosaic_virus wikiPageWikiLink Genome.
- Brome_mosaic_virus wikiPageWikiLink Helicase.
- Brome_mosaic_virus wikiPageWikiLink Hepatitis_E_virus.
- Brome_mosaic_virus wikiPageWikiLink Messenger_RNA.
- Brome_mosaic_virus wikiPageWikiLink Methyltransferase.
- Brome_mosaic_virus wikiPageWikiLink Monocotyledon.
- Brome_mosaic_virus wikiPageWikiLink Nanometre.
- Brome_mosaic_virus wikiPageWikiLink Plant_virus.
- Brome_mosaic_virus wikiPageWikiLink Poaceae.
- Brome_mosaic_virus wikiPageWikiLink RNA.
- Brome_mosaic_virus wikiPageWikiLink Regular_icosahedron.
- Brome_mosaic_virus wikiPageWikiLink Semliki_Forest_virus.
- Brome_mosaic_virus wikiPageWikiLink Sindbis_virus.
- Brome_mosaic_virus wikiPageWikiLink Tobacco_mosaic_virus.
- Brome_mosaic_virus wikiPageWikiLinkText "Brome mosaic virus (BMV)".
- Brome_mosaic_virus wikiPageWikiLinkText "Brome mosaic virus".
- Brome_mosaic_virus wikiPageWikiLinkText "Brome mosaic".
- Brome_mosaic_virus wikiPageWikiLinkText "brome mosaic virus".
- Brome_mosaic_virus familia "Bromoviridae".
- Brome_mosaic_virus genus "Bromovirus".
- Brome_mosaic_virus imageCaption "Crystal structure of Brome Mosaic Virus. PDB entry".
- Brome_mosaic_virus name "Brome mosaic virus".
- Brome_mosaic_virus species "Brome mosaic virus".
- Brome_mosaic_virus virusGroup "iv".
- Brome_mosaic_virus wikiPageUsesTemplate Template:PDBe.
- Brome_mosaic_virus wikiPageUsesTemplate Template:Reflist.
- Brome_mosaic_virus wikiPageUsesTemplate Template:Taxobox.
- Brome_mosaic_virus subject Category:Bromoviridae.
- Brome_mosaic_virus subject Category:Viral_plant_pathogens_and_diseases.
- Brome_mosaic_virus hypernym Virus.
- Brome_mosaic_virus type Species.
- Brome_mosaic_virus type Organism.
- Brome_mosaic_virus type Pathogen.
- Brome_mosaic_virus type Organism.
- Brome_mosaic_virus type Thing.
- Brome_mosaic_virus comment "Brome mosaic virus (BMV) is a small (28 nm, 86S), positive-stranded, icosahedral RNA plant virus belonging to the genus Bromovirus, family Bromoviridae, in the alphavirus-like superfamily.BMV commonly infects Bromus inermis (see Bromus) and other grasses, can be found almost anywhere wheat is grown, and thrives in areas with heavy foot or machinery traffic.".
- Brome_mosaic_virus label "Brome mosaic virus".
- Brome_mosaic_virus sameAs Q4163153.
- Brome_mosaic_virus sameAs فيروس_تبرقش_الشويعرة.
- Brome_mosaic_virus sameAs m.05jxbd.
- Brome_mosaic_virus sameAs Q4163153.
- Brome_mosaic_virus wasDerivedFrom Brome_mosaic_virus?oldid=701953170.
- Brome_mosaic_virus depiction Image1js9.png.
- Brome_mosaic_virus isPrimaryTopicOf Brome_mosaic_virus.
- Brome_mosaic_virus name "Brome mosaic virus".