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- Brain_natriuretic_peptide abstract "Brain natriuretic peptide or B-type natriuretic peptide (BNP) (also ventricular natriuretic peptide) is a 32-amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). The release of BNP is modulated by calcium ions. BNP is named as such because it was originally identified in extracts of porcine brain, although in humans it is produced mainly in the cardiac ventricles.BNP is secreted along with a 76-amino acid N-terminal fragment (NT-proBNP) that is biologically inactive. BNP binds to and activates the atrial natriuretic factor receptors NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity. The biological half-life of BNP, however, is twice as long as that of ANP, and that of NT-proBNP is even longer, making these peptides better targets than ANP for diagnostic blood testing.The physiologic actions of BNP are similar to those of ANP and include decrease in systemic vascular resistance and central venous pressure as well as an increase in natriuresis. The net effect of these peptides is a decrease in blood pressure due to the decrease in systemic vascular resistance and, thus, afterload. Additionally, the actions of both BNP and ANP result in a decrease in cardiac output due to an overall decrease in central venous pressure and preload as a result of the reduction in blood volume that follows natriuresis and diuresis.".
- Brain_natriuretic_peptide entrezgene "4879".
- Brain_natriuretic_peptide wikiPageExternalLink test.
- Brain_natriuretic_peptide wikiPageID "1784980".
- Brain_natriuretic_peptide wikiPageLength "26064".
- Brain_natriuretic_peptide wikiPageOutDegree "25".
- Brain_natriuretic_peptide wikiPageRevisionID "701222003".
- Brain_natriuretic_peptide wikiPageWikiLink Atrial_natriuretic_peptide.
- Brain_natriuretic_peptide wikiPageWikiLink Atrial_natriuretic_peptide_receptor.
- Brain_natriuretic_peptide wikiPageWikiLink Biological_half-life.
- Brain_natriuretic_peptide wikiPageWikiLink Category:Cardiology.
- Brain_natriuretic_peptide wikiPageWikiLink Circulatory_system.
- Brain_natriuretic_peptide wikiPageWikiLink Corin.
- Brain_natriuretic_peptide wikiPageWikiLink Furin.
- Brain_natriuretic_peptide wikiPageWikiLink Glycoprotein.
- Brain_natriuretic_peptide wikiPageWikiLink Heart.
- Brain_natriuretic_peptide wikiPageWikiLink Immunoassay.
- Brain_natriuretic_peptide wikiPageWikiLink N-terminal_prohormone_of_brain_natriuretic_peptide.
- Brain_natriuretic_peptide wikiPageWikiLink Natriuresis.
- Brain_natriuretic_peptide wikiPageWikiLink Natriuretic_peptide_precursor_C.
- Brain_natriuretic_peptide wikiPageWikiLink Nesiritide.
- Brain_natriuretic_peptide wikiPageWikiLink Pig.
- Brain_natriuretic_peptide wikiPageWikiLink Sensitivity_and_specificity.
- Brain_natriuretic_peptide wikiPageWikiLink Vascular_resistance.
- Brain_natriuretic_peptide wikiPageWikiLink Ventricle_(heart).
- Brain_natriuretic_peptide wikiPageWikiLinkText "B-type Natriuretic Peptide (BNP)".
- Brain_natriuretic_peptide wikiPageWikiLinkText "B-type natriuretic peptide".
- Brain_natriuretic_peptide wikiPageWikiLinkText "BNP".
- Brain_natriuretic_peptide wikiPageWikiLinkText "Brain natriuretic peptide".
- Brain_natriuretic_peptide wikiPageWikiLinkText "Brain_natriuretic_peptide".
- Brain_natriuretic_peptide wikiPageWikiLinkText "NPPB".
- Brain_natriuretic_peptide wikiPageWikiLinkText "brain natriuretic peptide".
- Brain_natriuretic_peptide wikiPageWikiLinkText "natriuretic peptide B".
- Brain_natriuretic_peptide wikiPageWikiLinkText "ventricular".
- Brain_natriuretic_peptide wikiPageUsesTemplate Template:Citation_needed.
- Brain_natriuretic_peptide wikiPageUsesTemplate Template:Cite_journal.
- Brain_natriuretic_peptide wikiPageUsesTemplate Template:Dubious.
- Brain_natriuretic_peptide wikiPageUsesTemplate Template:Hormones.
- Brain_natriuretic_peptide wikiPageUsesTemplate Template:MeshName.
- Brain_natriuretic_peptide wikiPageUsesTemplate Template:Nerve_tissue_protein.
- Brain_natriuretic_peptide wikiPageUsesTemplate Template:PBB.
- Brain_natriuretic_peptide wikiPageUsesTemplate Template:Refbegin.
- Brain_natriuretic_peptide wikiPageUsesTemplate Template:Refend.
- Brain_natriuretic_peptide wikiPageUsesTemplate Template:Reflist.
- Brain_natriuretic_peptide subject Category:Cardiology.
- Brain_natriuretic_peptide hypernym Polypeptide.
- Brain_natriuretic_peptide type Biomolecule.
- Brain_natriuretic_peptide type Protein.
- Brain_natriuretic_peptide type Redirect.
- Brain_natriuretic_peptide type Specialty.
- Brain_natriuretic_peptide type Thing.
- Brain_natriuretic_peptide type Q206229.
- Brain_natriuretic_peptide type Q8054.
- Brain_natriuretic_peptide comment "Brain natriuretic peptide or B-type natriuretic peptide (BNP) (also ventricular natriuretic peptide) is a 32-amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). The release of BNP is modulated by calcium ions.".
- Brain_natriuretic_peptide label "Brain natriuretic peptide".
- Brain_natriuretic_peptide sameAs Q14865348.
- Brain_natriuretic_peptide sameAs Brain_Natriuretic_Peptide.
- Brain_natriuretic_peptide sameAs Péptido_natriurético_cerebral.
- Brain_natriuretic_peptide sameAs B-tyypin_natriureettinen_peptidi.
- Brain_natriuretic_peptide sameAs Peptide_cérébral_natriurétique.
- Brain_natriuretic_peptide sameAs Péptido_natriurético_cerebral.
- Brain_natriuretic_peptide sameAs 脳性ナトリウム利尿ペプチド.
- Brain_natriuretic_peptide sameAs Brain_natriuretic_peptide.
- Brain_natriuretic_peptide sameAs Mózgowy_peptyd_natriuretyczny.
- Brain_natriuretic_peptide sameAs Peptídeo_natriurético_cerebral.
- Brain_natriuretic_peptide sameAs m.05wpp7.
- Brain_natriuretic_peptide sameAs Мозговой_натрийуретический_пептид.
- Brain_natriuretic_peptide sameAs Moždani_natriuretski_peptid.
- Brain_natriuretic_peptide sameAs Moždani_natriuretski_peptid.
- Brain_natriuretic_peptide sameAs B-typ_natriuretisk_peptid.
- Brain_natriuretic_peptide sameAs Q14865348.
- Brain_natriuretic_peptide wasDerivedFrom Brain_natriuretic_peptide?oldid=701222003.
- Brain_natriuretic_peptide isPrimaryTopicOf Brain_natriuretic_peptide.