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- Bradanicline abstract "Bradanicline (INN) (code name TC-5619) is a drug which was being developed by Targacept that acts as a partial agonist at the α7 subtype of the neural nicotinic acetylcholine receptors. It showed cognitive enhancing effects in animal studies, and was being developed through a collaboration between Targacept and AstraZeneca as a potential treatment for schizophrenia and attention deficit disorder. Phase I clinical trials were completed successfully, and it was in phase II trials.In May 2011, AstraZeneca declined to exercise its right to license the compound. In September 2012, Targacept ended its development of badanicline for the purpose of treating ADHD in adults. It was being studied for cognitive and memory enhancement.Bradanicline was discontinued for Alzheimer's disease and cognitive impairment in schizophrenia in late 2013. It was also discontinued for ADHD, and no longer seems to be being developed.".
- Bradanicline casNumber "639489-84-2".
- Bradanicline fdaUniiCode "UM3821998K".
- Bradanicline iupacName "N-[(2S,3R)-2-(Pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzofuran-2- carboxamide".
- Bradanicline pubchem "16727410".
- Bradanicline thumbnail Bradanicline.svg?width=300.
- Bradanicline wikiPageID "19476092".
- Bradanicline wikiPageLength "2784".
- Bradanicline wikiPageOutDegree "18".
- Bradanicline wikiPageRevisionID "701790238".
- Bradanicline wikiPageWikiLink Alpha-7_nicotinic_receptor.
- Bradanicline wikiPageWikiLink Alzheimers_disease.
- Bradanicline wikiPageWikiLink AstraZeneca.
- Bradanicline wikiPageWikiLink Attention_deficit_hyperactivity_disorder.
- Bradanicline wikiPageWikiLink Category:Antipsychotics.
- Bradanicline wikiPageWikiLink Category:Benzofurans.
- Bradanicline wikiPageWikiLink Category:Carboxamides.
- Bradanicline wikiPageWikiLink Category:Nicotinic_agonists.
- Bradanicline wikiPageWikiLink Category:Pyridines.
- Bradanicline wikiPageWikiLink Category:Quinuclidines.
- Bradanicline wikiPageWikiLink Category:Stimulants.
- Bradanicline wikiPageWikiLink Clinical_trial.
- Bradanicline wikiPageWikiLink Drug_development.
- Bradanicline wikiPageWikiLink International_nonproprietary_name.
- Bradanicline wikiPageWikiLink Nicotinic_acetylcholine_receptor.
- Bradanicline wikiPageWikiLink Partial_agonist.
- Bradanicline wikiPageWikiLink Schizophrenia.
- Bradanicline wikiPageWikiLink Targacept.
- Bradanicline wikiPageWikiLinkText "Bradanicline".
- Bradanicline wikiPageWikiLinkText "bradanicline".
- Bradanicline c "22".
- Bradanicline casNumber "639489".
- Bradanicline chembl "1258006".
- Bradanicline h "23".
- Bradanicline iupacName "N-[-2--1-azabicyclo[2.2.2]oct-3-yl]-1-benzofuran-2- carboxamide".
- Bradanicline molecularWeight "361.437".
- Bradanicline n "3".
- Bradanicline o "2".
- Bradanicline pubchem "16727410".
- Bradanicline smiles "C1CN2CCC1[C@@H]NCC4=CC5=CC=CC=C5O4".
- Bradanicline synonyms "TC-5619".
- Bradanicline unii "UM3821998K".
- Bradanicline verifiedrevid "444128206".
- Bradanicline width "200".
- Bradanicline wikiPageUsesTemplate Template:Cholinergics.
- Bradanicline wikiPageUsesTemplate Template:Drugbankcite.
- Bradanicline wikiPageUsesTemplate Template:Drugbox.
- Bradanicline wikiPageUsesTemplate Template:Fdacite.
- Bradanicline wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- Bradanicline wikiPageUsesTemplate Template:Nootropics.
- Bradanicline wikiPageUsesTemplate Template:Reflist.
- Bradanicline wikiPageUsesTemplate Template:Stimulants.
- Bradanicline subject Category:Antipsychotics.
- Bradanicline subject Category:Benzofurans.
- Bradanicline subject Category:Carboxamides.
- Bradanicline subject Category:Nicotinic_agonists.
- Bradanicline subject Category:Pyridines.
- Bradanicline subject Category:Quinuclidines.
- Bradanicline subject Category:Stimulants.
- Bradanicline hypernym Drug.
- Bradanicline type ChemicalSubstance.
- Bradanicline type Drug.
- Bradanicline type Group.
- Bradanicline type Agonist.
- Bradanicline type Amide.
- Bradanicline type Chemical.
- Bradanicline type Group.
- Bradanicline type Heterocycle.
- Bradanicline type Parasympathomimetic.
- Bradanicline type Psychoanaleptic.
- Bradanicline type Stimulant.
- Bradanicline type ChemicalObject.
- Bradanicline type Thing.
- Bradanicline type Q8386.
- Bradanicline comment "Bradanicline (INN) (code name TC-5619) is a drug which was being developed by Targacept that acts as a partial agonist at the α7 subtype of the neural nicotinic acetylcholine receptors. It showed cognitive enhancing effects in animal studies, and was being developed through a collaboration between Targacept and AstraZeneca as a potential treatment for schizophrenia and attention deficit disorder.".
- Bradanicline label "Bradanicline".
- Bradanicline sameAs Q7669595.
- Bradanicline sameAs m.04n3wqp.
- Bradanicline sameAs TC-5619.
- Bradanicline sameAs TC-5619.
- Bradanicline sameAs Q7669595.
- Bradanicline wasDerivedFrom Bradanicline?oldid=701790238.
- Bradanicline depiction Bradanicline.svg.
- Bradanicline isPrimaryTopicOf Bradanicline.