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- Bone_marrow_suppression abstract "Bone marrow suppression or myelotoxicity (adjective myelotoxic) or myelosuppression is the decrease in production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes). Bone marrow suppression is a serious side effect of chemotherapy and certain drugs affecting the immune system such as azathioprine. The risk is especially high in cytotoxic chemotherapy for leukemia.Non-steroidal anti-inflammatory drugs, in some rare instances, may also cause bone marrow suppression.The decrease in blood cell counts does not occur right at the start of chemotherapy because the drugs do not destroy the cells already in the bloodstream (these are not dividing rapidly). Instead, the drugs affect new blood cells that are being made by the bone marrow.When myelosuppression is severe, it is called myeloablation.Because the bone marrow is the manufacturing center of blood cells, the suppression of bone marrow activity causes a deficiency of blood cells. This condition can rapidly lead to life-threatening infection, as the body cannot produce leukocytes in response to invading bacteria and viruses, as well as leading to anaemia due to a lack of red blood cells and spontaneous severe bleeding due to deficiency of platelets.Parvovirus B19 inhibits erythropoiesis by lytically infecting RBC precursors in the bone marrow and is associated with a number of different diseases ranging from benign to severe. In immunocompromised patients, B19 infection may persist for months, leading to chronic anemia with B19 viremia due to chronic marrow suppression.Thiazide diuretics can also lead to bone marrow suppression as an adverse effect.".
- Bone_marrow_suppression wikiPageID "530505".
- Bone_marrow_suppression wikiPageLength "5636".
- Bone_marrow_suppression wikiPageOutDegree "34".
- Bone_marrow_suppression wikiPageRevisionID "690118455".
- Bone_marrow_suppression wikiPageWikiLink Anemia.
- Bone_marrow_suppression wikiPageWikiLink Antibiotics.
- Bone_marrow_suppression wikiPageWikiLink Azathioprine.
- Bone_marrow_suppression wikiPageWikiLink Bacteria.
- Bone_marrow_suppression wikiPageWikiLink Bone_marrow.
- Bone_marrow_suppression wikiPageWikiLink Category:Hematology.
- Bone_marrow_suppression wikiPageWikiLink Category:Oncology.
- Bone_marrow_suppression wikiPageWikiLink Chemotherapy.
- Bone_marrow_suppression wikiPageWikiLink Crohns_disease.
- Bone_marrow_suppression wikiPageWikiLink Erythropoiesis.
- Bone_marrow_suppression wikiPageWikiLink Granulocyte_colony-stimulating_factor.
- Bone_marrow_suppression wikiPageWikiLink Granulocyte_macrophage_colony-stimulating_factor.
- Bone_marrow_suppression wikiPageWikiLink Immune_system.
- Bone_marrow_suppression wikiPageWikiLink Immunodeficiency.
- Bone_marrow_suppression wikiPageWikiLink Infection.
- Bone_marrow_suppression wikiPageWikiLink Leukemia.
- Bone_marrow_suppression wikiPageWikiLink Mycophenolic_acid.
- Bone_marrow_suppression wikiPageWikiLink Neutropenia.
- Bone_marrow_suppression wikiPageWikiLink Nonsteroidal_anti-inflammatory_drug.
- Bone_marrow_suppression wikiPageWikiLink Parvovirus_B19.
- Bone_marrow_suppression wikiPageWikiLink Platelet.
- Bone_marrow_suppression wikiPageWikiLink Red_blood_cell.
- Bone_marrow_suppression wikiPageWikiLink Rheumatoid_arthritis.
- Bone_marrow_suppression wikiPageWikiLink Side_effect.
- Bone_marrow_suppression wikiPageWikiLink Thiazide.
- Bone_marrow_suppression wikiPageWikiLink Virus.
- Bone_marrow_suppression wikiPageWikiLink White_blood_cell.
- Bone_marrow_suppression wikiPageWikiLinkText "Bone marrow suppression".
- Bone_marrow_suppression wikiPageWikiLinkText "Myelosuppression".
- Bone_marrow_suppression wikiPageWikiLinkText "bone marrow depression".
- Bone_marrow_suppression wikiPageWikiLinkText "bone marrow suppression".
- Bone_marrow_suppression wikiPageWikiLinkText "bone marrow toxicity".
- Bone_marrow_suppression wikiPageWikiLinkText "suppresses the bone marrow".
- Bone_marrow_suppression wikiPageUsesTemplate Template:Cn.
- Bone_marrow_suppression wikiPageUsesTemplate Template:Refimprove.
- Bone_marrow_suppression wikiPageUsesTemplate Template:Reflist.
- Bone_marrow_suppression subject Category:Hematology.
- Bone_marrow_suppression subject Category:Oncology.
- Bone_marrow_suppression hypernym Decrease.
- Bone_marrow_suppression type Disease.
- Bone_marrow_suppression type Specialty.
- Bone_marrow_suppression comment "Bone marrow suppression or myelotoxicity (adjective myelotoxic) or myelosuppression is the decrease in production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes). Bone marrow suppression is a serious side effect of chemotherapy and certain drugs affecting the immune system such as azathioprine.".
- Bone_marrow_suppression label "Bone marrow suppression".
- Bone_marrow_suppression sameAs Q864868.
- Bone_marrow_suppression sameAs تثبيط_نقي_العظم.
- Bone_marrow_suppression sameAs Myelosuppression.
- Bone_marrow_suppression sameAs Mielosupresión.
- Bone_marrow_suppression sameAs نارسایی_مغز_استخوان.
- Bone_marrow_suppression sameAs Soppressione_del_midollo_osseo.
- Bone_marrow_suppression sameAs m.02m3ky.
- Bone_marrow_suppression sameAs Q864868.
- Bone_marrow_suppression sameAs 骨髓抑制.
- Bone_marrow_suppression wasDerivedFrom Bone_marrow_suppression?oldid=690118455.
- Bone_marrow_suppression isPrimaryTopicOf Bone_marrow_suppression.