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- Blood–gas_partition_coefficient abstract "Blood–gas partition coefficient, also known as Ostwald coefficient for blood–gas, is a term used in pharmacology to describe the solubility of inhaled general anesthetics in blood. The coefficient is defined as the ratio of the concentration in blood to the concentration in gas that is in contact with that blood, when the partial pressure in both compartments is equal. The coefficient, thence, has no units. The concentration of the anesthetic in blood includes the portion that is undissolved in plasma and the portion that is dissolved (bound to plasma proteins). The more soluble the inhaled anesthetic is in blood compared to in air, the more it binds to plasma proteins in the blood and the higher the blood–gas partition coefficient.It is inversely related to induction rate.Newer anesthetics (such as desflurane) typically have smaller blood-gas partition coefficients than older ones (such as ether); these are preferred because they lead to faster onset of anesthesia and faster emergence from anesthesia once application of the anesthetic is stopped. If an anesthetic has a high coefficient, then a large amount of it will have to be taken up in the body's blood before being passed on to the fatty (lipid) tissues of the brain where it can exert its effect.The potency of an anesthetic is associated with its lipid solubility which is measured by its oil/gas partition coefficient.Minimum Alveolar Concentration (MAC) is the concentration required to produce anaesthetic effects - an inverse indicator of anaesthetic potency.".
- Blood–gas_partition_coefficient wikiPageID "35737600".
- Blood–gas_partition_coefficient wikiPageLength "3997".
- Blood–gas_partition_coefficient wikiPageOutDegree "8".
- Blood–gas_partition_coefficient wikiPageRevisionID "680625099".
- Blood–gas_partition_coefficient wikiPageWikiLink Category:Anesthesia.
- Blood–gas_partition_coefficient wikiPageWikiLink Category:Pharmacokinetics.
- Blood–gas_partition_coefficient wikiPageWikiLink Desflurane.
- Blood–gas_partition_coefficient wikiPageWikiLink Ether.
- Blood–gas_partition_coefficient wikiPageWikiLink General_anaesthetic.
- Blood–gas_partition_coefficient wikiPageWikiLink Partition_coefficient.
- Blood–gas_partition_coefficient wikiPageWikiLink Pharmacology.
- Blood–gas_partition_coefficient wikiPageWikiLink Solubility.
- Blood–gas_partition_coefficient wikiPageWikiLinkText "Blood–gas partition coefficient".
- Blood–gas_partition_coefficient wikiPageUsesTemplate Template:Anesthesia.
- Blood–gas_partition_coefficient wikiPageUsesTemplate Template:Reflist.
- Blood–gas_partition_coefficient subject Category:Anesthesia.
- Blood–gas_partition_coefficient subject Category:Pharmacokinetics.
- Blood–gas_partition_coefficient hypernym Term.
- Blood–gas_partition_coefficient type Science.
- Blood–gas_partition_coefficient comment "Blood–gas partition coefficient, also known as Ostwald coefficient for blood–gas, is a term used in pharmacology to describe the solubility of inhaled general anesthetics in blood. The coefficient is defined as the ratio of the concentration in blood to the concentration in gas that is in contact with that blood, when the partial pressure in both compartments is equal. The coefficient, thence, has no units.".
- Blood–gas_partition_coefficient label "Blood–gas partition coefficient".
- Blood–gas_partition_coefficient sameAs Q4927528.
- Blood–gas_partition_coefficient sameAs m.0jt6csr.
- Blood–gas_partition_coefficient sameAs Q4927528.
- Blood–gas_partition_coefficient wasDerivedFrom Blood–gas_partition_coefficient?oldid=680625099.
- Blood–gas_partition_coefficient isPrimaryTopicOf Blood–gas_partition_coefficient.