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- Bing–Neel_syndrome abstract "Bing–Neel syndrome (BNS) is an extremely rare neurologic complication of Waldenström macroglobulinemia (WM). It was first described in 1936 by Jens Bing and Axel Valdemar Neel, who observed a case of 2 women, 56 and 39 years old, presenting with rapid neurodegeneration in the setting of hyperglobulinemia.It involves central nervous system infiltration by neoplastic lymphoplasmacytoid and plasma cells with or without cerebrospinal fluid (CSF) hyperglobulinemia. This increases blood viscosity, which impairs its circulation through small brain and eye blood vessels. Patients with BNS can be classified into Group A and Group B based on the presence of these cells within the brain parenchyma, leptomeninges, dura, and/or the CSF.Symptoms include episodes of confusion, slurred speech, headache, fatigue, ataxia, memory problems, nausea, vomiting, and extremity numbness.Complete blood count, electrolytes, and liver enzymes are normal in patients with Bing-Neel syndrome. Diagnosis can include lumbar puncture and magnetic resonance imaging (MRI) of the brain and spinal cord.Treatment involves central nervous system penetrating chemotherapy. Some significant improvement has been shown in patients as a result of cranial radiation treatment preceding a brief course of intrathecal chemotherapy. In Arkansas, a patient was treated with \"intrathecal chemotherapy with several cycles of systemic chemotherapy followed by autologous stem cell-supported high-dose therapy transplant\". The patient discontinued all treatment in 2009 and was still asymptomatic by the time a follow-up report was published in 2013.".
- Bing–Neel_syndrome wikiPageID "34852083".
- Bing–Neel_syndrome wikiPageLength "4208".
- Bing–Neel_syndrome wikiPageOutDegree "21".
- Bing–Neel_syndrome wikiPageRevisionID "659847850".
- Bing–Neel_syndrome wikiPageWikiLink Autotransplantation.
- Bing–Neel_syndrome wikiPageWikiLink Category:Hematologic_neoplasms.
- Bing–Neel_syndrome wikiPageWikiLink Category:Syndromes.
- Bing–Neel_syndrome wikiPageWikiLink Central_nervous_system.
- Bing–Neel_syndrome wikiPageWikiLink Cerebrospinal_fluid.
- Bing–Neel_syndrome wikiPageWikiLink Chemotherapy.
- Bing–Neel_syndrome wikiPageWikiLink Dura_mater.
- Bing–Neel_syndrome wikiPageWikiLink High-dose_chemotherapy_and_bone_marrow_transplant.
- Bing–Neel_syndrome wikiPageWikiLink Hyperglobulinemia.
- Bing–Neel_syndrome wikiPageWikiLink Intrathecal_administration.
- Bing–Neel_syndrome wikiPageWikiLink Lumbar_puncture.
- Bing–Neel_syndrome wikiPageWikiLink Magnetic_resonance_imaging.
- Bing–Neel_syndrome wikiPageWikiLink Meninges.
- Bing–Neel_syndrome wikiPageWikiLink Neurodegeneration.
- Bing–Neel_syndrome wikiPageWikiLink Neurology.
- Bing–Neel_syndrome wikiPageWikiLink Parenchyma.
- Bing–Neel_syndrome wikiPageWikiLink Plasma_cell.
- Bing–Neel_syndrome wikiPageWikiLink Radiation_therapy.
- Bing–Neel_syndrome wikiPageWikiLink Stem_cell.
- Bing–Neel_syndrome wikiPageWikiLink Waldenstrxc3xb6ms_macroglobulinemia.
- Bing–Neel_syndrome wikiPageWikiLinkText "Bing–Neel syndrome".
- Bing–Neel_syndrome diseasesdb "20944".
- Bing–Neel_syndrome name "Bing-Neel syndrome".
- Bing–Neel_syndrome wikiPageUsesTemplate Template:Cite_journal.
- Bing–Neel_syndrome wikiPageUsesTemplate Template:Infobox_disease.
- Bing–Neel_syndrome wikiPageUsesTemplate Template:Oncology-stub.
- Bing–Neel_syndrome wikiPageUsesTemplate Template:Reflist.
- Bing–Neel_syndrome subject Category:Hematologic_neoplasms.
- Bing–Neel_syndrome subject Category:Syndromes.
- Bing–Neel_syndrome type Disease.
- Bing–Neel_syndrome type Type.
- Bing–Neel_syndrome type Disorder.
- Bing–Neel_syndrome type Syndrome.
- Bing–Neel_syndrome type Type.
- Bing–Neel_syndrome type Thing.
- Bing–Neel_syndrome type Q12136.
- Bing–Neel_syndrome comment "Bing–Neel syndrome (BNS) is an extremely rare neurologic complication of Waldenström macroglobulinemia (WM). It was first described in 1936 by Jens Bing and Axel Valdemar Neel, who observed a case of 2 women, 56 and 39 years old, presenting with rapid neurodegeneration in the setting of hyperglobulinemia.It involves central nervous system infiltration by neoplastic lymphoplasmacytoid and plasma cells with or without cerebrospinal fluid (CSF) hyperglobulinemia.".
- Bing–Neel_syndrome label "Bing–Neel syndrome".
- Bing–Neel_syndrome sameAs Q4914327.
- Bing–Neel_syndrome sameAs m.0j46mnr.
- Bing–Neel_syndrome sameAs Q4914327.
- Bing–Neel_syndrome wasDerivedFrom Bing–Neel_syndrome?oldid=659847850.
- Bing–Neel_syndrome isPrimaryTopicOf Bing–Neel_syndrome.