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- Base_analog abstract "A base analog is chemical that can substitute for a normal nucleobase in nucleic acids.They are categorized in two separate groups, purine analogues and pyrimidine analogues.One of the most common base analogs is 5-bromouracil (5BU), the abnormal base found in the mutagenic nucleotide analog BrdU. When a nucleotide containing 5-bromouracil is incorporated into the DNA, it is most likely to pair with adenine; however, it can spontaneously shift into another isomer which pairs with a different nucleobase, guanine. If this happens during DNA replication, a guanine will be inserted as the opposite base analog, and in the next DNA replication, that guanine will pair with a cytosine. This results in a change in one base pair of DNA, specifically a transition mutation.".
- Base_analog thumbnail 5bu_2.png?width=300.
- Base_analog wikiPageID "487401".
- Base_analog wikiPageLength "1137".
- Base_analog wikiPageOutDegree "13".
- Base_analog wikiPageRevisionID "686912202".
- Base_analog wikiPageWikiLink 5-Bromouracil.
- Base_analog wikiPageWikiLink Antimetabolite.
- Base_analog wikiPageWikiLink Category:Nucleobases.
- Base_analog wikiPageWikiLink Guanine.
- Base_analog wikiPageWikiLink Isomer.
- Base_analog wikiPageWikiLink Mutation.
- Base_analog wikiPageWikiLink Nucleic_acid.
- Base_analog wikiPageWikiLink Nucleobase.
- Base_analog wikiPageWikiLink Purine_analogue.
- Base_analog wikiPageWikiLink Pyrimidine_analogue.
- Base_analog wikiPageWikiLink Transition_(genetics).
- Base_analog wikiPageWikiLink File:5bu_2.png.
- Base_analog wikiPageWikiLinkText "'''Base Analogs'''".
- Base_analog wikiPageWikiLinkText "Base analog".
- Base_analog wikiPageWikiLinkText "analog".
- Base_analog wikiPageWikiLinkText "base analog".
- Base_analog wikiPageWikiLinkText "nucleoside analog".
- Base_analog subject Category:Nucleobases.
- Base_analog hypernym Chemical.
- Base_analog type ChemicalCompound.
- Base_analog comment "A base analog is chemical that can substitute for a normal nucleobase in nucleic acids.They are categorized in two separate groups, purine analogues and pyrimidine analogues.One of the most common base analogs is 5-bromouracil (5BU), the abnormal base found in the mutagenic nucleotide analog BrdU.".
- Base_analog label "Base analog".
- Base_analog sameAs Q809940.
- Base_analog sameAs Basenanaloga.
- Base_analog sameAs m.02gdlx.
- Base_analog sameAs Q809940.
- Base_analog sameAs 碱基类似物.
- Base_analog wasDerivedFrom Base_analog?oldid=686912202.
- Base_analog depiction 5bu_2.png.
- Base_analog isPrimaryTopicOf Base_analog.