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- Balapiravir abstract "Balapiravir (R-1626, Ro4588161) is an experimental antiviral drug which acts as a polymerase inhibitor. There were efforts to develop it as a potential treatment for hepatitis C, and it was subsequently also studied in Dengue fever, but was not found to be useful. Lower doses failed to produce measurable reductions in viral load, while higher doses produced serious side effects such as lymphopenia which precluded further development of the drug. Subsequent research found that excess cytokine production triggered by Dengue virus infection prevented the conversion of the balapiravir prodrug to its active form, thereby blocking the activity of the drug.".
- Balapiravir casNumber "690270-29-2".
- Balapiravir iupacName "[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-2-azido-3,4-bis(2-methylpropanoyloxy)oxolan-2-yl]methyl 2-methylpropanoate".
- Balapiravir pubchem "11691726".
- Balapiravir thumbnail Balapiravir_structure.png?width=300.
- Balapiravir wikiPageID "42683217".
- Balapiravir wikiPageLength "2564".
- Balapiravir wikiPageOutDegree "8".
- Balapiravir wikiPageRevisionID "706666750".
- Balapiravir wikiPageWikiLink Category:Antivirals.
- Balapiravir wikiPageWikiLink Category:Dengue_fever.
- Balapiravir wikiPageWikiLink Cytokine.
- Balapiravir wikiPageWikiLink Dengue_fever.
- Balapiravir wikiPageWikiLink Hepatitis_C.
- Balapiravir wikiPageWikiLink Lymphocytopenia.
- Balapiravir wikiPageWikiLink Polymerase_chain_reaction_inhibitors.
- Balapiravir wikiPageWikiLink Prodrug.
- Balapiravir wikiPageWikiLinkText "Balapiravir".
- Balapiravir c "21".
- Balapiravir casNumber "690270".
- Balapiravir chembl "550936".
- Balapiravir chemspiderid "9866453".
- Balapiravir h "30".
- Balapiravir inchi "1".
- Balapiravir inchikey "VKXWOLCNTHXCLF-DXEZIKHYBB".
- Balapiravir iupacName "[-5--2-azido-3,4-bisoxolan-2-yl]methyl 2-methylpropanoate".
- Balapiravir kegg "D09582".
- Balapiravir legalStatus "Investigational New Drug".
- Balapiravir molecularWeight "494.497".
- Balapiravir n "6".
- Balapiravir o "8".
- Balapiravir pubchem "11691726".
- Balapiravir smiles "O=c1ncccn1C2OCCC2OCCC".
- Balapiravir stdinchi "1".
- Balapiravir stdinchikey "VKXWOLCNTHXCLF-DXEZIKHYSA-N".
- Balapiravir wikiPageUsesTemplate Template:Antiinfective-drug-stub.
- Balapiravir wikiPageUsesTemplate Template:Cascite.
- Balapiravir wikiPageUsesTemplate Template:Drugbankcite.
- Balapiravir wikiPageUsesTemplate Template:Drugbox.
- Balapiravir wikiPageUsesTemplate Template:Reflist.
- Balapiravir subject Category:Antivirals.
- Balapiravir subject Category:Dengue_fever.
- Balapiravir hypernym Drug.
- Balapiravir type ChemicalSubstance.
- Balapiravir type Drug.
- Balapiravir type ChemicalObject.
- Balapiravir type Thing.
- Balapiravir type Q8386.
- Balapiravir comment "Balapiravir (R-1626, Ro4588161) is an experimental antiviral drug which acts as a polymerase inhibitor. There were efforts to develop it as a potential treatment for hepatitis C, and it was subsequently also studied in Dengue fever, but was not found to be useful. Lower doses failed to produce measurable reductions in viral load, while higher doses produced serious side effects such as lymphopenia which precluded further development of the drug.".
- Balapiravir label "Balapiravir".
- Balapiravir sameAs Q17070900.
- Balapiravir sameAs m.010hlhzq.
- Balapiravir sameAs Q17070900.
- Balapiravir wasDerivedFrom Balapiravir?oldid=706666750.
- Balapiravir depiction Balapiravir_structure.png.
- Balapiravir isPrimaryTopicOf Balapiravir.