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- BAY_38-7271 abstract "Originally synthesized by chemist Wayne E. Kenney, BAY 38-7271 (KN 38-7271) is a drug which is a cannabinoid receptor agonist developed by Bayer AG. It has analgesic and neuroprotective effects and is used in scientific research, with proposed uses in the treatment of traumatic brain injury. It is a full agonist with around the same potency as CP 55,940 in animal studies, and has fairly high affinity for both CB1 and CB2 receptors, with Ki values of 2.91nM at CB1 and 4.24nM at CB2. It has now been licensed to KeyNeurotek Pharmaceuticals for clinical development, and is currently in Phase II trials. But its development appears stopped.".
- BAY_38-7271 casNumber "212188-60-8".
- BAY_38-7271 iupacName "(−)-(R)-3-(2-Hydroxymethylindanyl-4-oxy)phenyl-4,4,4-trifluorobutyl-1-sulfonate".
- BAY_38-7271 pubchem "9845561".
- BAY_38-7271 thumbnail BAY38-7271.svg?width=300.
- BAY_38-7271 wikiPageID "16567277".
- BAY_38-7271 wikiPageLength "3730".
- BAY_38-7271 wikiPageOutDegree "18".
- BAY_38-7271 wikiPageRevisionID "703379738".
- BAY_38-7271 wikiPageWikiLink Agonist.
- BAY_38-7271 wikiPageWikiLink Analgesic.
- BAY_38-7271 wikiPageWikiLink Bayer.
- BAY_38-7271 wikiPageWikiLink CP_55,940.
- BAY_38-7271 wikiPageWikiLink Cannabinoid_receptor.
- BAY_38-7271 wikiPageWikiLink Cannabinoid_receptor_type_1.
- BAY_38-7271 wikiPageWikiLink Cannabinoid_receptor_type_2.
- BAY_38-7271 wikiPageWikiLink Category:Alcohols.
- BAY_38-7271 wikiPageWikiLink Category:Cannabinoids.
- BAY_38-7271 wikiPageWikiLink Category:Indanes.
- BAY_38-7271 wikiPageWikiLink Category:Organofluorides.
- BAY_38-7271 wikiPageWikiLink Category:Phenol_ethers.
- BAY_38-7271 wikiPageWikiLink Category:Sulfonates.
- BAY_38-7271 wikiPageWikiLink Dissociation_constant.
- BAY_38-7271 wikiPageWikiLink KeyNeurotek_Pharmaceuticals.
- BAY_38-7271 wikiPageWikiLink Neuroprotection.
- BAY_38-7271 wikiPageWikiLink Phases_of_clinical_research.
- BAY_38-7271 wikiPageWikiLink Traumatic_brain_injury.
- BAY_38-7271 wikiPageWikiLinkText "BAY 38-7271".
- BAY_38-7271 c "20".
- BAY_38-7271 casNumber "212188".
- BAY_38-7271 chembl "1668508".
- BAY_38-7271 chemspiderid "8021275".
- BAY_38-7271 f "3".
- BAY_38-7271 h "21".
- BAY_38-7271 inchi "1".
- BAY_38-7271 inchikey "XJURALZPEJKKOV-CQSZACIVBW".
- BAY_38-7271 iupacName "--3-phenyl-4,4,4-trifluorobutyl-1-sulfonate".
- BAY_38-7271 legalCa "Schedule II".
- BAY_38-7271 molecularWeight "430.437".
- BAY_38-7271 o "5".
- BAY_38-7271 pubchem "9845561".
- BAY_38-7271 s "1".
- BAY_38-7271 smiles "FCCCCSOc3ccccc3".
- BAY_38-7271 stdinchi "1".
- BAY_38-7271 stdinchikey "XJURALZPEJKKOV-CQSZACIVSA-N".
- BAY_38-7271 verifiedfields "changed".
- BAY_38-7271 verifiedrevid "461342730".
- BAY_38-7271 watchedfields "changed".
- BAY_38-7271 width "220".
- BAY_38-7271 wikiPageUsesTemplate Template:Cannabinoids.
- BAY_38-7271 wikiPageUsesTemplate Template:Cascite.
- BAY_38-7271 wikiPageUsesTemplate Template:Chemspidercite.
- BAY_38-7271 wikiPageUsesTemplate Template:Drugbox.
- BAY_38-7271 wikiPageUsesTemplate Template:Ebicite.
- BAY_38-7271 wikiPageUsesTemplate Template:Stdinchicite.
- BAY_38-7271 subject Category:Alcohols.
- BAY_38-7271 subject Category:Cannabinoids.
- BAY_38-7271 subject Category:Indanes.
- BAY_38-7271 subject Category:Organofluorides.
- BAY_38-7271 subject Category:Phenol_ethers.
- BAY_38-7271 subject Category:Sulfonates.
- BAY_38-7271 hypernym Drug.
- BAY_38-7271 type ChemicalSubstance.
- BAY_38-7271 type Drug.
- BAY_38-7271 type Alcohol.
- BAY_38-7271 type Cannabinoid.
- BAY_38-7271 type Drug.
- BAY_38-7271 type Ether.
- BAY_38-7271 type Hydrocarbon.
- BAY_38-7271 type Organofluoride.
- BAY_38-7271 type Organohalide.
- BAY_38-7271 type Sulfonate.
- BAY_38-7271 type Organofluoride.
- BAY_38-7271 type Organohalide.
- BAY_38-7271 type ChemicalObject.
- BAY_38-7271 type Thing.
- BAY_38-7271 type Q8386.
- BAY_38-7271 comment "Originally synthesized by chemist Wayne E. Kenney, BAY 38-7271 (KN 38-7271) is a drug which is a cannabinoid receptor agonist developed by Bayer AG. It has analgesic and neuroprotective effects and is used in scientific research, with proposed uses in the treatment of traumatic brain injury. It is a full agonist with around the same potency as CP 55,940 in animal studies, and has fairly high affinity for both CB1 and CB2 receptors, with Ki values of 2.91nM at CB1 and 4.24nM at CB2.".
- BAY_38-7271 label "BAY 38-7271".
- BAY_38-7271 sameAs Q4834697.
- BAY_38-7271 sameAs m.03ybp59.
- BAY_38-7271 sameAs BAY_38-7271.
- BAY_38-7271 sameAs BAY_38-7271.
- BAY_38-7271 sameAs Q4834697.
- BAY_38-7271 wasDerivedFrom BAY_38-7271?oldid=703379738.
- BAY_38-7271 depiction BAY38-7271.svg.
- BAY_38-7271 isPrimaryTopicOf BAY_38-7271.