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- B4GALT2 abstract "Beta-1,4-galactosyltransferase 2 is an enzyme that in humans is encoded by the B4GALT2 gene.This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Two transcript variants encoding the same protein have been found for this gene.".
- B4GALT2 entrezgene "8704".
- B4GALT2 wikiPageID "15180967".
- B4GALT2 wikiPageLength "7669".
- B4GALT2 wikiPageOutDegree "25".
- B4GALT2 wikiPageRevisionID "659800903".
- B4GALT2 wikiPageWikiLink Alpha-lactalbumin.
- B4GALT2 wikiPageWikiLink Biological_membrane.
- B4GALT2 wikiPageWikiLink Biosynthesis.
- B4GALT2 wikiPageWikiLink Carbohydrate.
- B4GALT2 wikiPageWikiLink Enzyme.
- B4GALT2 wikiPageWikiLink Galactosyltransferase.
- B4GALT2 wikiPageWikiLink Gene.
- B4GALT2 wikiPageWikiLink Glucose.
- B4GALT2 wikiPageWikiLink Glycoconjugate.
- B4GALT2 wikiPageWikiLink Glycolipid.
- B4GALT2 wikiPageWikiLink Glycoprotein.
- B4GALT2 wikiPageWikiLink Golgi_apparatus.
- B4GALT2 wikiPageWikiLink Homology_(biology).
- B4GALT2 wikiPageWikiLink Hydrophobe.
- B4GALT2 wikiPageWikiLink Mammary_gland.
- B4GALT2 wikiPageWikiLink Membrane_protein.
- B4GALT2 wikiPageWikiLink N-Acetylglucosamine.
- B4GALT2 wikiPageWikiLink N-terminus.
- B4GALT2 wikiPageWikiLink Signal_peptide.
- B4GALT2 wikiPageWikiLink Substrate_(chemistry).
- B4GALT2 wikiPageWikiLink Uridine_diphosphate_galactose.
- B4GALT2 wikiPageWikiLinkText "B4GALT2".
- B4GALT2 requireManualInspection "no".
- B4GALT2 summaryText "This gene is one of seven beta-1,4-galactosyltransferase genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Two transcript variants encoding the same protein have been found for this gene.".
- B4GALT2 updateCitations "yes".
- B4GALT2 updatePage "yes".
- B4GALT2 updateProteinBox "yes".
- B4GALT2 updateSummary "yes".
- B4GALT2 wikiPageUsesTemplate Template:Cite_journal.
- B4GALT2 wikiPageUsesTemplate Template:Gene-1-stub.
- B4GALT2 wikiPageUsesTemplate Template:PBB.
- B4GALT2 wikiPageUsesTemplate Template:PBB_Controls.
- B4GALT2 wikiPageUsesTemplate Template:PBB_Further_reading.
- B4GALT2 wikiPageUsesTemplate Template:PBB_Summary.
- B4GALT2 wikiPageUsesTemplate Template:Refbegin.
- B4GALT2 wikiPageUsesTemplate Template:Refend.
- B4GALT2 wikiPageUsesTemplate Template:Reflist.
- B4GALT2 hypernym Enzyme.
- B4GALT2 type Biomolecule.
- B4GALT2 type Protein.
- B4GALT2 type Thing.
- B4GALT2 type Q206229.
- B4GALT2 type Q8054.
- B4GALT2 comment "Beta-1,4-galactosyltransferase 2 is an enzyme that in humans is encoded by the B4GALT2 gene.This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl.".
- B4GALT2 label "B4GALT2".
- B4GALT2 sameAs Q18033229.
- B4GALT2 sameAs m.03hl0t8.
- B4GALT2 sameAs Q18033229.
- B4GALT2 wasDerivedFrom B4GALT2?oldid=659800903.
- B4GALT2 isPrimaryTopicOf B4GALT2.