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- B-cell_receptor abstract "The B-cell receptor or BCR is a transmembrane receptor protein located on the outer surface of B cells. The receptor's binding moiety is composed of a membrane-bound antibody that, like all antibodies, has a unique and randomly determined antigen-binding site (see V(D)J recombination).When a B cell is activated by its first encounter with an antigen that binds to its receptor (its \"cognate antigen\"), the cell proliferates and differentiates to generate a population of antibody-secreting plasma B cells and memory B cells. The B cell receptor (BCR) has two crucial functions upon interaction with the antigen. One function is signal transduction, involving changes in receptor oligomerization. The second function is to mediate internalization for subsequent processing of the antigen and presentation of peptides to helper T cells.BCR functions are required for normal antibody production, and defects in BCR signal transduction may lead to immunodeficency, and B-cell malignancy.".
- B-cell_receptor thumbnail Bcellreceptor.svg?width=300.
- B-cell_receptor wikiPageID "5221850".
- B-cell_receptor wikiPageLength "10301".
- B-cell_receptor wikiPageOutDegree "39".
- B-cell_receptor wikiPageRevisionID "696891235".
- B-cell_receptor wikiPageWikiLink Antibody.
- B-cell_receptor wikiPageWikiLink Antigen.
- B-cell_receptor wikiPageWikiLink BCL10.
- B-cell_receptor wikiPageWikiLink B_cell.
- B-cell_receptor wikiPageWikiLink CARD11.
- B-cell_receptor wikiPageWikiLink CD79.
- B-cell_receptor wikiPageWikiLink CD79A.
- B-cell_receptor wikiPageWikiLink CD79B.
- B-cell_receptor wikiPageWikiLink Caspase.
- B-cell_receptor wikiPageWikiLink Category:Lymphocytes.
- B-cell_receptor wikiPageWikiLink Category:Receptors.
- B-cell_receptor wikiPageWikiLink Cell_membrane.
- B-cell_receptor wikiPageWikiLink Cytosol.
- B-cell_receptor wikiPageWikiLink Diglyceride.
- B-cell_receptor wikiPageWikiLink Disulfide.
- B-cell_receptor wikiPageWikiLink Endoplasmic_reticulum.
- B-cell_receptor wikiPageWikiLink Immunological_synapse.
- B-cell_receptor wikiPageWikiLink Immunoreceptor_tyrosine-based_activation_motif.
- B-cell_receptor wikiPageWikiLink Inositol_trisphosphate.
- B-cell_receptor wikiPageWikiLink Integral_membrane_protein.
- B-cell_receptor wikiPageWikiLink Ion_channel.
- B-cell_receptor wikiPageWikiLink IκB_kinase.
- B-cell_receptor wikiPageWikiLink MALT1.
- B-cell_receptor wikiPageWikiLink MAP3K7.
- B-cell_receptor wikiPageWikiLink Memory_B_cell.
- B-cell_receptor wikiPageWikiLink Moiety_(chemistry).
- B-cell_receptor wikiPageWikiLink NF-κB.
- B-cell_receptor wikiPageWikiLink PLCG1.
- B-cell_receptor wikiPageWikiLink PRKCB1.
- B-cell_receptor wikiPageWikiLink Phosphatidylinositol_4,5-bisphosphate.
- B-cell_receptor wikiPageWikiLink Plasma_cell.
- B-cell_receptor wikiPageWikiLink Protein_dimer.
- B-cell_receptor wikiPageWikiLink Receptor_(biochemistry).
- B-cell_receptor wikiPageWikiLink Second_messenger_system.
- B-cell_receptor wikiPageWikiLink Transmembrane_protein.
- B-cell_receptor wikiPageWikiLink V(D)J_recombination.
- B-cell_receptor wikiPageWikiLink File:Bcellreceptor.svg.
- B-cell_receptor wikiPageWikiLinkText "B cell receptors (BCRs)".
- B-cell_receptor wikiPageWikiLinkText "B".
- B-cell_receptor wikiPageWikiLinkText "B-cell co-receptor".
- B-cell_receptor wikiPageWikiLinkText "B-cell receptor".
- B-cell_receptor wikiPageWikiLinkText "B-cell".
- B-cell_receptor wikiPageWikiLinkText "BCR".
- B-cell_receptor wikiPageUsesTemplate Template:Immune_receptors.
- B-cell_receptor wikiPageUsesTemplate Template:MeshName.
- B-cell_receptor wikiPageUsesTemplate Template:Reflist.
- B-cell_receptor subject Category:Lymphocytes.
- B-cell_receptor subject Category:Receptors.
- B-cell_receptor hypernym Protein.
- B-cell_receptor type Protein.
- B-cell_receptor comment "The B-cell receptor or BCR is a transmembrane receptor protein located on the outer surface of B cells.".
- B-cell_receptor label "B-cell receptor".
- B-cell_receptor sameAs Q1100474.
- B-cell_receptor sameAs Receptor_dels_limfòcits_B.
- B-cell_receptor sameAs B-buněčný_receptor.
- B-cell_receptor sameAs B-Zell-Rezeptor.
- B-cell_receptor sameAs Receptor_de_linfocito_B.
- B-cell_receptor sameAs Récepteur_des_cellules_B.
- B-cell_receptor sameAs Receptor_de_células_B.
- B-cell_receptor sameAs Recettore_delle_cellule_B.
- B-cell_receptor sameAs Receptor_limfocytów_B.
- B-cell_receptor sameAs m.0d8ljj.
- B-cell_receptor sameAs B-клеточный_рецептор.
- B-cell_receptor sameAs Q1100474.
- B-cell_receptor wasDerivedFrom B-cell_receptor?oldid=696891235.
- B-cell_receptor depiction Bcellreceptor.svg.
- B-cell_receptor isPrimaryTopicOf B-cell_receptor.