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- Aspergillomarasmine_A abstract "Aspergillomarasmine A is an polyamino acid naturally produced by the mold Aspergillus versicolor. The substance has been reported to inhibit two antibiotic resistance carbapenemase proteins in bacteria, New Delhi metallo-beta-lactamase 1 (NDM-1) and Verona integron-encoded metallo-beta-lactamase (VIM-2), and make those antibiotic-resistant bacteria susceptible to antibiotics. Aspergillomarasmine A is toxic to leaves of barley and other plants, being termed as \"Toxin C\" when produced by Pyrenophora teres.The molecule is a tetracarboxylic acid with four -COOH groups. One section of the molecule is the amino acid aspartic acid. This has two alanine molecules attached. Aspergillomarasmine B differs in that the last alanine is replaced by glycine.The crystalline substance was first isolated in 1956, but its name was given until 1965.In addition to Aspergillus versicolor, aspergillomarasmine A is also produced by the ascomycete Pyrenophora teres where it acts as a toxin in the barley net-spot blotch disease. In P. teres, a biosynthetic precursor of aspergillomarasmine A, L,L-N-(2-amino-2-carboxyethyl)-aspartic acid has also been isolated and found to contribute to the phytotoxic properties of this microbe. This precursor, aspergillomarasmine A itself, and a lactam form (anhydroaspergillomarasmine A) are together termed the marasmines.Other producers of aspergillomarasmine A include Aspergillus flavus, Aspergillus oryzae, Colletotrichum gloeosporioides, and Fusarium oxysporum.In mice the LD50 toxic dose of aspergillomarasmine A is 159.8 mg/kg.".
- Aspergillomarasmine_A iupacName "(R-(R*,R*))-N-(2-((2-Amino-2-carboxyethyl)amino)-2-carboxyethyl)-L-aspartic acid".
- Aspergillomarasmine_A thumbnail Aspergillomarasmine_A.svg?width=300.
- Aspergillomarasmine_A wikiPageID "43149099".
- Aspergillomarasmine_A wikiPageLength "8542".
- Aspergillomarasmine_A wikiPageOutDegree "37".
- Aspergillomarasmine_A wikiPageRevisionID "703991036".
- Aspergillomarasmine_A wikiPageWikiLink 2,3-diamino-propionic_acid.
- Aspergillomarasmine_A wikiPageWikiLink Alanine.
- Aspergillomarasmine_A wikiPageWikiLink Antimicrobial_resistance.
- Aspergillomarasmine_A wikiPageWikiLink Aspartic_acid.
- Aspergillomarasmine_A wikiPageWikiLink Aspergillomarasmine_B.
- Aspergillomarasmine_A wikiPageWikiLink Aspergillus_flavus.
- Aspergillomarasmine_A wikiPageWikiLink Aspergillus_oryzae.
- Aspergillomarasmine_A wikiPageWikiLink Aspergillus_versicolor.
- Aspergillomarasmine_A wikiPageWikiLink Barley.
- Aspergillomarasmine_A wikiPageWikiLink Beta-lactamase.
- Aspergillomarasmine_A wikiPageWikiLink Carboxylic_acid.
- Aspergillomarasmine_A wikiPageWikiLink Category:Antibiotic_resistance.
- Aspergillomarasmine_A wikiPageWikiLink Chelation.
- Aspergillomarasmine_A wikiPageWikiLink Chemical_decomposition.
- Aspergillomarasmine_A wikiPageWikiLink Deamination.
- Aspergillomarasmine_A wikiPageWikiLink Dissociation_constant.
- Aspergillomarasmine_A wikiPageWikiLink Endothelin_converting_enzyme_1.
- Aspergillomarasmine_A wikiPageWikiLink Ferric.
- Aspergillomarasmine_A wikiPageWikiLink Fusarium_oxysporum.
- Aspergillomarasmine_A wikiPageWikiLink Glomerella_cingulata.
- Aspergillomarasmine_A wikiPageWikiLink Glycine.
- Aspergillomarasmine_A wikiPageWikiLink Hydrolysis.
- Aspergillomarasmine_A wikiPageWikiLink Isoserine.
- Aspergillomarasmine_A wikiPageWikiLink Lactam.
- Aspergillomarasmine_A wikiPageWikiLink Median_lethal_dose.
- Aspergillomarasmine_A wikiPageWikiLink Metalloproteinase.
- Aspergillomarasmine_A wikiPageWikiLink New_Delhi_metallo-beta-lactamase_1.
- Aspergillomarasmine_A wikiPageWikiLink Ninhydrin.
- Aspergillomarasmine_A wikiPageWikiLink Pyrenophora_teres.
- Aspergillomarasmine_A wikiPageWikiLink Solvent.
- Aspergillomarasmine_A wikiPageWikiLink Titration.
- Aspergillomarasmine_A wikiPageWikiLink Trifluoroacetic_acid.
- Aspergillomarasmine_A wikiPageWikiLink VIM-2.
- Aspergillomarasmine_A wikiPageWikiLink Verona_integron-encoded_metallo-beta-lactamase.
- Aspergillomarasmine_A wikiPageWikiLinkText "Aspergillomarasmine A".
- Aspergillomarasmine_A wikiPageWikiLinkText "aspergillomarasmine A".
- Aspergillomarasmine_A imagefile "Aspergillomarasmine A.svg".
- Aspergillomarasmine_A imagesize "200".
- Aspergillomarasmine_A imagesize "250".
- Aspergillomarasmine_A iupacname "-N--L-aspartic acid".
- Aspergillomarasmine_A watchedfields "changed".
- Aspergillomarasmine_A wikiPageUsesTemplate Template:Cascite.
- Aspergillomarasmine_A wikiPageUsesTemplate Template:Chembox.
- Aspergillomarasmine_A wikiPageUsesTemplate Template:Chembox_Identifiers.
- Aspergillomarasmine_A wikiPageUsesTemplate Template:Chembox_Properties.
- Aspergillomarasmine_A wikiPageUsesTemplate Template:Clarification_needed.
- Aspergillomarasmine_A wikiPageUsesTemplate Template:Cn.
- Aspergillomarasmine_A wikiPageUsesTemplate Template:Contradict-inline.
- Aspergillomarasmine_A wikiPageUsesTemplate Template:Huh.
- Aspergillomarasmine_A wikiPageUsesTemplate Template:Reflist.
- Aspergillomarasmine_A wikiPageUsesTemplate Template:Why.
- Aspergillomarasmine_A subject Category:Antibiotic_resistance.
- Aspergillomarasmine_A hypernym Acid.
- Aspergillomarasmine_A type ChemicalCompound.
- Aspergillomarasmine_A type ChemicalSubstance.
- Aspergillomarasmine_A type ChemicalObject.
- Aspergillomarasmine_A type Thing.
- Aspergillomarasmine_A type Q11173.
- Aspergillomarasmine_A comment "Aspergillomarasmine A is an polyamino acid naturally produced by the mold Aspergillus versicolor. The substance has been reported to inhibit two antibiotic resistance carbapenemase proteins in bacteria, New Delhi metallo-beta-lactamase 1 (NDM-1) and Verona integron-encoded metallo-beta-lactamase (VIM-2), and make those antibiotic-resistant bacteria susceptible to antibiotics.".
- Aspergillomarasmine_A label "Aspergillomarasmine A".
- Aspergillomarasmine_A sameAs Q18205331.
- Aspergillomarasmine_A sameAs m.01115flf.
- Aspergillomarasmine_A sameAs Q18205331.
- Aspergillomarasmine_A wasDerivedFrom Aspergillomarasmine_A?oldid=703991036.
- Aspergillomarasmine_A depiction Aspergillomarasmine_A.svg.
- Aspergillomarasmine_A isPrimaryTopicOf Aspergillomarasmine_A.