Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Aspartic_protease> ?p ?o }
- Aspartic_protease abstract "Aspartic proteases are a catalytic type of protease enzymes that use an activated water molecule bound to one or more aspartate residues for catalysis of their peptide substrates. In general, they have two highly conserved aspartates in the active site and are optimally active at acidic pH. Nearly all known aspartyl proteases are inhibited by pepstatin.Aspartic endopeptidases EC 3.4.23. of vertebrate, fungal and retroviral origin have been characterised. More recently, aspartic endopeptidases associated with the processing of bacterial type 4 prepilin and archaean preflagellin have been described.Eukaryotic aspartic proteases include pepsins, cathepsins, and renins. They have a two-domain structure, arising from ancestral duplication. Retroviral and retrotransposon proteases (Pfam PF00077) are much smaller and appear tobe homologous to a single domain of the eukaryotic aspartyl proteases. Each domain contributes a catalytic Asp residue, with an extended active site cleft localized between the two lobes of the molecule. One lobe has probably evolved from the other through a gene duplication event in the distant past. In modern-day enzymes, although the three-dimensional structures are very similar, the amino acid sequences are more divergent, except for the catalytic site motif, which is very conserved. The presence and position of disulfide bridges are other conserved features of aspartic peptidases.".
- Aspartic_protease symbol "A1_Propeptide".
- Aspartic_protease symbol "Asp".
- Aspartic_protease thumbnail PDB_1lyb_EBI.jpg?width=300.
- Aspartic_protease wikiPageExternalLink A.
- Aspartic_protease wikiPageExternalLink famsum?family=A1.
- Aspartic_protease wikiPageID "7748624".
- Aspartic_protease wikiPageLength "9041".
- Aspartic_protease wikiPageOutDegree "83".
- Aspartic_protease wikiPageRevisionID "705417533".
- Aspartic_protease wikiPageWikiLink Acid.
- Aspartic_protease wikiPageWikiLink Acid–base_reaction.
- Aspartic_protease wikiPageWikiLink Active_site.
- Aspartic_protease wikiPageWikiLink Alpha_helix.
- Aspartic_protease wikiPageWikiLink Amide.
- Aspartic_protease wikiPageWikiLink Animal.
- Aspartic_protease wikiPageWikiLink Aspartic_acid.
- Aspartic_protease wikiPageWikiLink Beta-secretase_1.
- Aspartic_protease wikiPageWikiLink Beta-secretase_2.
- Aspartic_protease wikiPageWikiLink Carbonyl.
- Aspartic_protease wikiPageWikiLink Category:EC_3.4.23.
- Aspartic_protease wikiPageWikiLink Category:Peripheral_membrane_proteins.
- Aspartic_protease wikiPageWikiLink Category:Protein_domains.
- Aspartic_protease wikiPageWikiLink Category:Protein_families.
- Aspartic_protease wikiPageWikiLink Cathepsin.
- Aspartic_protease wikiPageWikiLink Cathepsin_D.
- Aspartic_protease wikiPageWikiLink Cathepsin_E.
- Aspartic_protease wikiPageWikiLink Chymosin.
- Aspartic_protease wikiPageWikiLink Conformational_isomerism.
- Aspartic_protease wikiPageWikiLink Conserved_sequence.
- Aspartic_protease wikiPageWikiLink Convergent_evolution.
- Aspartic_protease wikiPageWikiLink Cysteine_protease.
- Aspartic_protease wikiPageWikiLink Enzyme.
- Aspartic_protease wikiPageWikiLink Enzyme_catalysis.
- Aspartic_protease wikiPageWikiLink Eukaryote.
- Aspartic_protease wikiPageWikiLink GPR_endopeptidase.
- Aspartic_protease wikiPageWikiLink Gastricsin.
- Aspartic_protease wikiPageWikiLink Glutamic_protease.
- Aspartic_protease wikiPageWikiLink HIV.
- Aspartic_protease wikiPageWikiLink HIV-1_protease.
- Aspartic_protease wikiPageWikiLink Hydrogen_bond.
- Aspartic_protease wikiPageWikiLink MEROPS.
- Aspartic_protease wikiPageWikiLink NAPSA.
- Aspartic_protease wikiPageWikiLink Nepenthesin.
- Aspartic_protease wikiPageWikiLink Nucleophile.
- Aspartic_protease wikiPageWikiLink Omptin.
- Aspartic_protease wikiPageWikiLink Oxyanion.
- Aspartic_protease wikiPageWikiLink PGA5.
- Aspartic_protease wikiPageWikiLink PH.
- Aspartic_protease wikiPageWikiLink Pepsin.
- Aspartic_protease wikiPageWikiLink Pepstatin.
- Aspartic_protease wikiPageWikiLink Peptide_sequence.
- Aspartic_protease wikiPageWikiLink Plasmepsin.
- Aspartic_protease wikiPageWikiLink Presenilin.
- Aspartic_protease wikiPageWikiLink Protease.
- Aspartic_protease wikiPageWikiLink Protein_family.
- Aspartic_protease wikiPageWikiLink Protein_precursor.
- Aspartic_protease wikiPageWikiLink Protein_superfamily.
- Aspartic_protease wikiPageWikiLink Reaction_intermediate.
- Aspartic_protease wikiPageWikiLink Renin.
- Aspartic_protease wikiPageWikiLink Residue_(chemistry).
- Aspartic_protease wikiPageWikiLink Retrotransposon.
- Aspartic_protease wikiPageWikiLink Scissile_bond.
- Aspartic_protease wikiPageWikiLink Sequence_motif.
- Aspartic_protease wikiPageWikiLink Serine_protease.
- Aspartic_protease wikiPageWikiLink Signal_peptidase_II.
- Aspartic_protease wikiPageWikiLink Signal_peptide.
- Aspartic_protease wikiPageWikiLink Tetrahedron.
- Aspartic_protease wikiPageWikiLink The_Proteolysis_Map.
- Aspartic_protease wikiPageWikiLink File:Aspartyl_protease_mechanism.png.
- Aspartic_protease wikiPageWikiLinkText "Aspartic protease".
- Aspartic_protease wikiPageWikiLinkText "aspartic protease".
- Aspartic_protease wikiPageWikiLinkText "aspartic-".
- Aspartic_protease caption "Structures of native and inhibited forms of human cathepsin D.".
- Aspartic_protease caption "crystal and molecular structures of human progastricsin at 1.62 angstroms resolution".
- Aspartic_protease interpro "IPR001461".
- Aspartic_protease interpro "IPR012848".
- Aspartic_protease name "A1_Propeptide".
- Aspartic_protease name "Eukaryotic aspartyl protease".
- Aspartic_protease opmFamily "108".
- Aspartic_protease opmProtein "1".
- Aspartic_protease pfam "PF00026".
- Aspartic_protease pfam "PF07966".
- Aspartic_protease prosite "PDOC00128".
- Aspartic_protease scop "1".
- Aspartic_protease symbol "A1_Propeptide".
- Aspartic_protease symbol "Asp".
- Aspartic_protease wikiPageUsesTemplate Template:Aspartic_acid_proteases.
- Aspartic_protease wikiPageUsesTemplate Template:EC_number.
- Aspartic_protease wikiPageUsesTemplate Template:Enzymes.
- Aspartic_protease wikiPageUsesTemplate Template:Infobox_protein_family.
- Aspartic_protease wikiPageUsesTemplate Template:InterPro_content.
- Aspartic_protease wikiPageUsesTemplate Template:MeshName.
- Aspartic_protease wikiPageUsesTemplate Template:Pfam.
- Aspartic_protease wikiPageUsesTemplate Template:Pfam_box.
- Aspartic_protease wikiPageUsesTemplate Template:Portal_bar.
- Aspartic_protease wikiPageUsesTemplate Template:Proteases.
- Aspartic_protease wikiPageUsesTemplate Template:Reflist.
- Aspartic_protease subject Category:EC_3.4.23.
- Aspartic_protease subject Category:Peripheral_membrane_proteins.