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- Ars_operon abstract "In molecular biology, the ars operon is an operon found in several bacterial taxon. It is required for the detoxification of arsenate, arsenite, and antimonite. This system transports arsenite and antimonite out of the cell. The pump is composed of two polypeptides, the products of the arsA and arsB genes. This two-subunit enzyme produces resistance to arsenite and antimonite. Arsenate, however, must first be reduced to arsenite before it is extruded. A third gene, arsC, expands the substrate specificity to allow for arsenate pumping and resistance. ArsC is an approximately 150-residue arsenate reductase that uses reduced glutathione (GSH) to convert arsenate to arsenite with a redox active cysteine residue in the active site. ArsC forms an active quaternary complex with GSH, arsenate, and glutaredoxin 1 (Grx1). The three ligands must be present simultaneously for reduction to occur.".
- Ars_operon symbol "ArsA_ATPase".
- Ars_operon symbol "ArsB".
- Ars_operon symbol "ArsC".
- Ars_operon symbol "ArsD".
- Ars_operon thumbnail PDB_1rw1_EBI.jpg?width=300.
- Ars_operon wikiPageID "32148595".
- Ars_operon wikiPageLength "7136".
- Ars_operon wikiPageOutDegree "49".
- Ars_operon wikiPageRevisionID "627504083".
- Ars_operon wikiPageWikiLink Active_site.
- Ars_operon wikiPageWikiLink Alpha_helix.
- Ars_operon wikiPageWikiLink Bacteria.
- Ars_operon wikiPageWikiLink Base_pair.
- Ars_operon wikiPageWikiLink Beta_sheet.
- Ars_operon wikiPageWikiLink Binding_site.
- Ars_operon wikiPageWikiLink Biomolecular_structure.
- Ars_operon wikiPageWikiLink Category:Protein_families.
- Ars_operon wikiPageWikiLink Cell_(biology).
- Ars_operon wikiPageWikiLink Conserved_sequence.
- Ars_operon wikiPageWikiLink Cysteine.
- Ars_operon wikiPageWikiLink Detoxification.
- Ars_operon wikiPageWikiLink Dissociation_(chemistry).
- Ars_operon wikiPageWikiLink Enzyme.
- Ars_operon wikiPageWikiLink Gene.
- Ars_operon wikiPageWikiLink Glutaredoxin.
- Ars_operon wikiPageWikiLink Glutathione.
- Ars_operon wikiPageWikiLink Gram-positive_bacteria.
- Ars_operon wikiPageWikiLink Homology_(biology).
- Ars_operon wikiPageWikiLink Hydrophobe.
- Ars_operon wikiPageWikiLink Ligand.
- Ars_operon wikiPageWikiLink Multiprotein_complex.
- Ars_operon wikiPageWikiLink Operon.
- Ars_operon wikiPageWikiLink Protein.
- Ars_operon wikiPageWikiLink Protein_dimer.
- Ars_operon wikiPageWikiLink Protein_folding.
- Ars_operon wikiPageWikiLink Redox.
- Ars_operon wikiPageWikiLink Reductase.
- Ars_operon wikiPageWikiLink Repressor.
- Ars_operon wikiPageWikiLink Residue_(chemistry).
- Ars_operon wikiPageWikiLink Stress_(biology).
- Ars_operon wikiPageWikiLink Substrate_(chemistry).
- Ars_operon wikiPageWikiLink Thioredoxin.
- Ars_operon wikiPageWikiLink Trans-acting.
- Ars_operon wikiPageWikiLink Transcription_(genetics).
- Ars_operon wikiPageWikiLink Transcription_factor.
- Ars_operon wikiPageWikiLink Transcriptional_regulation.
- Ars_operon wikiPageWikiLink Vicinal_(chemistry).
- Ars_operon wikiPageWikiLinkText "Ars operon".
- Ars_operon caption "yffb protein".
- Ars_operon interpro "IPR000802".
- Ars_operon interpro "IPR006660".
- Ars_operon interpro "IPR010712".
- Ars_operon name "Anion-transporting ATPase".
- Ars_operon name "ArsB".
- Ars_operon name "ArsC".
- Ars_operon name "ArsD".
- Ars_operon pfam "PF02040".
- Ars_operon pfam "PF02374".
- Ars_operon pfam "PF03960".
- Ars_operon pfam "PF06953".
- Ars_operon pfamClan "CL0023".
- Ars_operon pfamClan "CL0172".
- Ars_operon pfamClan "CL0182".
- Ars_operon scop "1".
- Ars_operon scop "777600.0".
- Ars_operon symbol "ArsA_ATPase".
- Ars_operon symbol "ArsB".
- Ars_operon symbol "ArsC".
- Ars_operon symbol "ArsD".
- Ars_operon tcdb "3".
- Ars_operon wikiPageUsesTemplate Template:Infobox_protein_family.
- Ars_operon wikiPageUsesTemplate Template:InterPro_content.
- Ars_operon wikiPageUsesTemplate Template:Reflist.
- Ars_operon subject Category:Protein_families.
- Ars_operon hypernym Operon.
- Ars_operon type Biomolecule.
- Ars_operon type Protein.
- Ars_operon type Chemical.
- Ars_operon type Thing.
- Ars_operon type Q206229.
- Ars_operon type Q8054.
- Ars_operon comment "In molecular biology, the ars operon is an operon found in several bacterial taxon. It is required for the detoxification of arsenate, arsenite, and antimonite. This system transports arsenite and antimonite out of the cell. The pump is composed of two polypeptides, the products of the arsA and arsB genes. This two-subunit enzyme produces resistance to arsenite and antimonite. Arsenate, however, must first be reduced to arsenite before it is extruded.".
- Ars_operon label "Ars operon".
- Ars_operon sameAs Q4796324.
- Ars_operon sameAs m.0gw_5xf.
- Ars_operon sameAs Q4796324.
- Ars_operon wasDerivedFrom Ars_operon?oldid=627504083.
- Ars_operon depiction PDB_1rw1_EBI.jpg.
- Ars_operon isPrimaryTopicOf Ars_operon.