Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Anticancer_gene> ?p ?o }
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- Anticancer_gene abstract "Anticancer genes act in a dominant fashion: when ectopically overexpressed they specifically destroy tumour cells without harming normal cells. This cell destruction can come in various modes such as apoptosis, mitotic catastrophe followed by apoptosis or necrosis, and autophagy. Anticancer genes have only recently emerged from studies on cancer cells. Anticancer genes comprise Apoptin, a gene encoded by the chicken anaemia virus genome which was the first anti-cancer gene isolated. Brevinin-2R is a short anti-microbial peptide of only 25 amino acids, a so-called non-hemolytic defensin, isolated from the skin of the frog species Rana ridibunda. The adenovirus E4orf4 is the second known viral protein with tumour-selective cell killing capabilities. HAMLET encodes the milk protein α-lactalbumin and is active against cancer cells only when complexed with oleic acid. Mda-7 (also known as IL-24) encodes a secreted cytokine and belongs to the IL-10 gene family. Noxa, is a BH3-only protein of the Bcl-2 family, has recently been discovered as a specific killer of breast cancer cells. Parvovirus-H1 NS1 is another viral protein carrying tumour-selective apoptosis capabilities. ORCTL3, a cation transporter, was recently discovered as a novel anti-cancer gene. Par-4 encodes a protein that features a leucine zipper and mediates many diverse signals for apoptosis at its endogenous expression level. TRAIL (TNF related apoptosis-inducing ligand) is a member of the TNF family of apoptosis-inducing ligands Some of these genes are in clinical development. TRAIL, Mda-7, HAMLET are the clinically most advanced anti-cancer genes. They are currently tested in clinical trials I and II, all other anti-cancer genes are in pre-clinical studies.".
- Anticancer_gene wikiPageID "34556489".
- Anticancer_gene wikiPageLength "3938".
- Anticancer_gene wikiPageOutDegree "24".
- Anticancer_gene wikiPageRevisionID "620745944".
- Anticancer_gene wikiPageWikiLink Amino_acid.
- Anticancer_gene wikiPageWikiLink Antimicrobial.
- Anticancer_gene wikiPageWikiLink Apoptosis.
- Anticancer_gene wikiPageWikiLink Autophagy.
- Anticancer_gene wikiPageWikiLink Bcl-2.
- Anticancer_gene wikiPageWikiLink Breast_cancer.
- Anticancer_gene wikiPageWikiLink Category:Genetics.
- Anticancer_gene wikiPageWikiLink Category:Oncology.
- Anticancer_gene wikiPageWikiLink Cell_(biology).
- Anticancer_gene wikiPageWikiLink Cell_death.
- Anticancer_gene wikiPageWikiLink Cytokine.
- Anticancer_gene wikiPageWikiLink Defensin.
- Anticancer_gene wikiPageWikiLink Ectopic_expression.
- Anticancer_gene wikiPageWikiLink Genome.
- Anticancer_gene wikiPageWikiLink Hemolysis.
- Anticancer_gene wikiPageWikiLink Lactalbumin.
- Anticancer_gene wikiPageWikiLink Leucine.
- Anticancer_gene wikiPageWikiLink Milk.
- Anticancer_gene wikiPageWikiLink Mitotic_catastrophe.
- Anticancer_gene wikiPageWikiLink Necrosis.
- Anticancer_gene wikiPageWikiLink Neoplasm.
- Anticancer_gene wikiPageWikiLink Oleic_acid.
- Anticancer_gene wikiPageWikiLink Transport_protein.
- Anticancer_gene wikiPageWikiLink Viral_protein.
- Anticancer_gene wikiPageWikiLinkText "Anticancer gene".
- Anticancer_gene wikiPageUsesTemplate Template:Doi.
- Anticancer_gene wikiPageUsesTemplate Template:Reflist.
- Anticancer_gene subject Category:Genetics.
- Anticancer_gene subject Category:Oncology.
- Anticancer_gene type Specialty.
- Anticancer_gene comment "Anticancer genes act in a dominant fashion: when ectopically overexpressed they specifically destroy tumour cells without harming normal cells. This cell destruction can come in various modes such as apoptosis, mitotic catastrophe followed by apoptosis or necrosis, and autophagy. Anticancer genes have only recently emerged from studies on cancer cells. Anticancer genes comprise Apoptin, a gene encoded by the chicken anaemia virus genome which was the first anti-cancer gene isolated.".
- Anticancer_gene label "Anticancer gene".
- Anticancer_gene sameAs Q4774587.
- Anticancer_gene sameAs m.0j28x7q.
- Anticancer_gene sameAs Q4774587.
- Anticancer_gene wasDerivedFrom Anticancer_gene?oldid=620745944.
- Anticancer_gene isPrimaryTopicOf Anticancer_gene.