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- Anti_vascular_endothelial_growth_factor_therapy abstract "Anti vascular endothelial growth factor therapy, also known as anti-VEGF therapy or anti-VEGF medication, is the use of medications that block vascular endothelial growth factor. This is done in the treatment of certain cancers and in age-related macular degeneration. They can involve monoclonal antibodies such as bevacizumab, antibody derivatives such as ranibizumab (Lucentis), or orally-available small molecules that inhibit the tyrosine kinases stimulated by VEGF: lapatinib, sunitinib, sorafenib, axitinib, and pazopanib. (Some of these therapies target VEGF receptors rather than the VEGFs.) THC and cannabidiol both inhibit VEGF and slow Glioma growth.Both antibody-based compounds are commercialized. The first three orally available compounds are commercialized, as well. The latter two (axitinib and pazopanib) are in clinical trials.Bergers and Hanahan concluded in 2008 that anti-VEGF drugs can show therapeutic efficacy in mouse models of cancer and in an increasing number of human cancers. But, \"the benefits are at best transitory and are followed by a restoration of tumour growth and progression.\"Later studies into the consequences of VEGF inhibitor use have shown that, although they can reduce the growth of primary tumours, VEGF inhibitors can concomitantly promote invasiveness and metastasis of tumours.AZ2171 (cediranib), a multi-targeted tyrosine kinase inhibitor has been shown to have anti-edema effects by reducing the permeability and aiding in vascular normalization.A 2014 Cochrane Systematic Review studied the effectiveness of ranibizumab and pegaptanib, on patients suffering from macular edema caused by central retinal vein occlusion. Participants on both treatment groups showed improvement in visual acuity measures and a reduction in macular edema symptoms over six months.".
- Anti_vascular_endothelial_growth_factor_therapy wikiPageID "48878156".
- Anti_vascular_endothelial_growth_factor_therapy wikiPageLength "10051".
- Anti_vascular_endothelial_growth_factor_therapy wikiPageOutDegree "28".
- Anti_vascular_endothelial_growth_factor_therapy wikiPageRevisionID "701527149".
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Axitinib.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Bevacizumab.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Cediranib.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Central_retinal_vein_occlusion.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Cochrane_(organisation).
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Diabetes_mellitus.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Granulosa_cell.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Lapatinib.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Macular_degeneration.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Off-label_use.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Ovarian_hyperstimulation_syndrome.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Pazopanib.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Pegaptanib.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Photodynamic_therapy.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Ranibizumab.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Sorafenib.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Sunitinib.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Thiazolidinedione.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Tyrosine_kinase.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink VEGF_receptors.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Vascular_endothelial_growth_factor.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLink Verteporfin.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageWikiLinkText "Anti vascular endothelial growth factor therapy".
- Anti_vascular_endothelial_growth_factor_therapy wikiPageUsesTemplate Template:Citation_needed.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageUsesTemplate Template:Uncategorized.
- Anti_vascular_endothelial_growth_factor_therapy wikiPageUsesTemplate Template:Which.
- Anti_vascular_endothelial_growth_factor_therapy hypernym Use.
- Anti_vascular_endothelial_growth_factor_therapy comment "Anti vascular endothelial growth factor therapy, also known as anti-VEGF therapy or anti-VEGF medication, is the use of medications that block vascular endothelial growth factor. This is done in the treatment of certain cancers and in age-related macular degeneration.".
- Anti_vascular_endothelial_growth_factor_therapy label "Anti vascular endothelial growth factor therapy".
- Anti_vascular_endothelial_growth_factor_therapy wasDerivedFrom Anti_vascular_endothelial_growth_factor_therapy?oldid=701527149.
- Anti_vascular_endothelial_growth_factor_therapy isPrimaryTopicOf Anti_vascular_endothelial_growth_factor_therapy.