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- Annular_lipid_shell abstract "Annular lipids or shell lipids (also called boundary lipids) represent a select set of lipids or lipidic molecules which preferentially 'bind' or stick to the surface of membrane proteins in biological cells. They constitute a layer, or an annulus/ shell, of lipids which are highly immobilized due to the existence of strong lipid-protein (binding) interactions. Polar headgroups of these lipids bind to the hydrophilic part of the membrane protein(s) at the inner and outer surfaces of lipid bilayer membrane. The hydrophobic surface of the membrane proteins is bound to the apposed lipid fatty acid chains of the membrane bilayer. For integral membrane proteins spanning the thickness of the membrane bilayer, these annular/shell lipids act like a lubricating layer on the proteins' surfaces, thereby facilitating almost free rotation and lateral diffusion of membrane proteins within the 2-dimensional expanse of the biological membrane(s). Outside the layer of shell/annular lipids, lipids are not tied down to protein molecules. However, they may be slightly restricted in their segmental motion freedom due to mild peer pressure of protein molecules, if present in high concentration, which arises from extended influence of protein-lipid interaction. Membrane areas away from protein molecules contain lamellar phase bulk lipids, which are largely free from any restraining effects due to protein-lipid interactions. Thermal denaturation of membrane proteins may destroy the secondary and tertiary structure of membrane proteins, exposing newer surfaces to membrane lipids and therefore increasing the number of lipids molecules in the annulus/shell layer. This phenomenon can be studied by the spin label electron paramagnetic resonance technique.".
- Annular_lipid_shell wikiPageExternalLink a004705.full.
- Annular_lipid_shell wikiPageExternalLink YashRoy_R_C_1991_Protein_heat_denaturation_and_study_of_membrane_lipid-protein_inteactions_by_spin_label_ESR._Jounal_of_Biochemical_and_Biophysical_Methods._Vol._22_No._1_pp._55-59.
- Annular_lipid_shell wikiPageID "43114391".
- Annular_lipid_shell wikiPageLength "2430".
- Annular_lipid_shell wikiPageOutDegree "17".
- Annular_lipid_shell wikiPageRevisionID "633082709".
- Annular_lipid_shell wikiPageWikiLink Category:Lipids.
- Annular_lipid_shell wikiPageWikiLink Cell_(biology).
- Annular_lipid_shell wikiPageWikiLink Electron_paramagnetic_resonance.
- Annular_lipid_shell wikiPageWikiLink Fatty_acid.
- Annular_lipid_shell wikiPageWikiLink Integral_membrane_protein.
- Annular_lipid_shell wikiPageWikiLink Lamellar_phase.
- Annular_lipid_shell wikiPageWikiLink Lipid.
- Annular_lipid_shell wikiPageWikiLink Lipid_bilayer.
- Annular_lipid_shell wikiPageWikiLink Membrane_lipids.
- Annular_lipid_shell wikiPageWikiLink Membrane_protein.
- Annular_lipid_shell wikiPageWikiLink Protein–lipid_interaction.
- Annular_lipid_shell wikiPageWikiLink Spin_label.
- Annular_lipid_shell wikiPageWikiLinkText "Annular lipid shell".
- Annular_lipid_shell wikiPageWikiLinkText "annular lipid shell".
- Annular_lipid_shell subject Category:Lipids.
- Annular_lipid_shell comment "Annular lipids or shell lipids (also called boundary lipids) represent a select set of lipids or lipidic molecules which preferentially 'bind' or stick to the surface of membrane proteins in biological cells. They constitute a layer, or an annulus/ shell, of lipids which are highly immobilized due to the existence of strong lipid-protein (binding) interactions.".
- Annular_lipid_shell label "Annular lipid shell".
- Annular_lipid_shell sameAs Q18352524.
- Annular_lipid_shell sameAs m.01111yc7.
- Annular_lipid_shell sameAs Q18352524.
- Annular_lipid_shell wasDerivedFrom Annular_lipid_shell?oldid=633082709.
- Annular_lipid_shell isPrimaryTopicOf Annular_lipid_shell.