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- Ancestry-informative_marker abstract "An ancestry-informative marker (AIM) is a set of polymorphisms for a locus, generally from humans, which exhibits substantially different frequencies between populations from different geographical regions. By using a number of AIMs one can estimate the geographical origins of the ancestors of an individual and ascertain what proportion of ancestry is derived from each geographical region. By using a suite of these markers more or less evenly spaced across the genome, they can be used in a cost-effective way to discover novel genes underlying complex diseases in a technique called admixture mapping or mapping by admixture linkage disequilibrium. There are an estimated 15 million SNP (Single-nucleotide polymorphism) sites (out of roughly 3 billion base pairs, or about 0.4%) from among which AIMs may potentially be selected.As one example, the Duffy Null allele (FY*0) has a frequency of almost 100% of Sub-Saharan Africans, but occurs very infrequently in populations outside of this region. A person having this allele is thus more likely to have Sub-Saharan African ancestors. Collections of AIMs have been developed that can estimate the geographical origins of ancestors from within Europe.".
- Ancestry-informative_marker thumbnail Bauchet_European_clusters.png?width=300.
- Ancestry-informative_marker wikiPageExternalLink shriver01.pdf.
- Ancestry-informative_marker wikiPageExternalLink science.
- Ancestry-informative_marker wikiPageExternalLink snps.html.
- Ancestry-informative_marker wikiPageExternalLink snp_summary.cgi.
- Ancestry-informative_marker wikiPageID "3636956".
- Ancestry-informative_marker wikiPageLength "2457".
- Ancestry-informative_marker wikiPageOutDegree "9".
- Ancestry-informative_marker wikiPageRevisionID "699659702".
- Ancestry-informative_marker wikiPageWikiLink Allele.
- Ancestry-informative_marker wikiPageWikiLink Category:Applied_genetics.
- Ancestry-informative_marker wikiPageWikiLink Category:Health_sciences.
- Ancestry-informative_marker wikiPageWikiLink Duffy_antigen_system.
- Ancestry-informative_marker wikiPageWikiLink Genetic_admixture.
- Ancestry-informative_marker wikiPageWikiLink Race_and_genetics.
- Ancestry-informative_marker wikiPageWikiLink SLC24A5.
- Ancestry-informative_marker wikiPageWikiLink Single-nucleotide_polymorphism.
- Ancestry-informative_marker wikiPageWikiLink File:Bauchet_European_clusters.png.
- Ancestry-informative_marker wikiPageWikiLinkText "Ancestry-informative marker".
- Ancestry-informative_marker wikiPageWikiLinkText "ancestral informative markers".
- Ancestry-informative_marker wikiPageWikiLinkText "ancestry-informative marker".
- Ancestry-informative_marker wikiPageUsesTemplate Template:Reflist.
- Ancestry-informative_marker subject Category:Applied_genetics.
- Ancestry-informative_marker subject Category:Health_sciences.
- Ancestry-informative_marker hypernym Set.
- Ancestry-informative_marker type Science.
- Ancestry-informative_marker comment "An ancestry-informative marker (AIM) is a set of polymorphisms for a locus, generally from humans, which exhibits substantially different frequencies between populations from different geographical regions. By using a number of AIMs one can estimate the geographical origins of the ancestors of an individual and ascertain what proportion of ancestry is derived from each geographical region.".
- Ancestry-informative_marker label "Ancestry-informative marker".
- Ancestry-informative_marker sameAs Q4752570.
- Ancestry-informative_marker sameAs m.09rg52.
- Ancestry-informative_marker sameAs Q4752570.
- Ancestry-informative_marker wasDerivedFrom Ancestry-informative_marker?oldid=699659702.
- Ancestry-informative_marker depiction Bauchet_European_clusters.png.
- Ancestry-informative_marker isPrimaryTopicOf Ancestry-informative_marker.