Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Amphetamine> ?p ?o }
- Amphetamine abstract "Amphetamine (contracted from alpha‑methylphenethylamine) is a potent central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity. Amphetamine was discovered in 1887 and exists as two enantiomers: levoamphetamine and dextroamphetamine. Amphetamine properly refers to a specific chemical, the racemic free base, which is equal parts of the two enantiomers, levoamphetamine and dextroamphetamine, in their pure amine forms. However, the term is frequently used informally to refer to any combination of the enantiomers, or to either of them alone. Historically, it has been used to treat nasal congestion and depression. Amphetamine is also used as a performance and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant. It is a prescription drug in many countries, and unauthorized possession and distribution of amphetamine are often tightly controlled due to the significant health risks associated with recreational use.The first pharmaceutical amphetamine was Benzedrine, a brand of inhalers used to treat a variety of conditions. Currently, pharmaceutical amphetamine is prescribed as racemic amphetamine, Adderall, dextroamphetamine, or the inactive prodrug lisdexamfetamine. Amphetamine, through activation of a trace amine receptor, increases monoamine and excitatory neurotransmitter activity in the brain, with its most pronounced effects targeting the catecholamine neurotransmitters norepinephrine and dopamine. At therapeutic doses, this causes emotional and cognitive effects such as euphoria, change in libido, increased wakefulness, and improved cognitive control. It induces physical effects such as decreased reaction time, fatigue resistance, and increased muscle strength.Much larger doses of amphetamine may impair cognitive function and induce rapid muscle breakdown. Drug addiction is a serious risk with large recreational doses, but rarely arises from medical use. Very high doses can result in psychosis (e.g., delusions and paranoia) which rarely occurs at therapeutic doses even during long-term use. Recreational doses are generally much larger than prescribed therapeutic doses and carry a far greater risk of serious side effects.Amphetamine belongs to the phenethylamine class. It is also the parent compound of its own structural class, the substituted amphetamines, which includes prominent substances such as bupropion, cathinone, MDMA (ecstasy), and methamphetamine. As a member of the phenethylamine class, amphetamine is also chemically related to the naturally occurring trace amine neuromodulators, specifically phenethylamine and N-methylphenethylamine, both of which are produced within the human body. Phenethylamine is the parent compound of amphetamine, while N-methylphenethylamine is a constitutional isomer that differs only in the placement of the methyl group.".
- Amphetamine thumbnail Racemic_amphetamine_2.svg?width=300.
- Amphetamine wikiPageExternalLink detail.go?type=gene&acc=9607&qid=2119242.
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- Amphetamine wikiPageRevisionID "707444842".
- Amphetamine wikiPageWikiLink 1,1-Bi-2-naphthol.
- Amphetamine wikiPageWikiLink 4-Hydroxyamphetamine.
- Amphetamine wikiPageWikiLink 4-Hydroxyphenylacetone.
- Amphetamine wikiPageWikiLink 5-HT1A_receptor.
- Amphetamine wikiPageWikiLink Acetamide.
- Amphetamine wikiPageWikiLink Acetonitrile.
- Amphetamine wikiPageWikiLink Acetylcholine.
- Amphetamine wikiPageWikiLink Acid_dissociation_constant.
- Amphetamine wikiPageWikiLink Action_potential.
- Amphetamine wikiPageWikiLink Adderall.
- Amphetamine wikiPageWikiLink Addiction.
- Amphetamine wikiPageWikiLink Adenylyl_cyclase.
- Amphetamine wikiPageWikiLink Adjuvant_therapy.
- Amphetamine wikiPageWikiLink Adrenocorticotropic_hormone.
- Amphetamine wikiPageWikiLink Aerobic_exercise.
- Amphetamine wikiPageWikiLink Agonist.
- Amphetamine wikiPageWikiLink Alcoholism.
- Amphetamine wikiPageWikiLink Alertness.
- Amphetamine wikiPageWikiLink Allyl_chloride.
- Amphetamine wikiPageWikiLink Alpha-2_adrenergic_receptor.
- Amphetamine wikiPageWikiLink Alpha_and_beta_carbon.
- Amphetamine wikiPageWikiLink Amine.
- Amphetamine wikiPageWikiLink Ammonia.
- Amphetamine wikiPageWikiLink Analgesic.
- Amphetamine wikiPageWikiLink Anorexia_nervosa.
- Amphetamine wikiPageWikiLink Antidepressant.
- Amphetamine wikiPageWikiLink Antihypertensive_drug.
- Amphetamine wikiPageWikiLink Antipsychotic.
- Amphetamine wikiPageWikiLink Anxiety.
- Amphetamine wikiPageWikiLink Aphrodisiac.
- Amphetamine wikiPageWikiLink Aromatic_L-amino_acid_decarboxylase.
- Amphetamine wikiPageWikiLink Arousal.
- Amphetamine wikiPageWikiLink Arteriosclerosis.
- Amphetamine wikiPageWikiLink Astrocyte.
- Amphetamine wikiPageWikiLink Attention_deficit_hyperactivity_disorder.
- Amphetamine wikiPageWikiLink Autoreceptor.
- Amphetamine wikiPageWikiLink Autoxidation.
- Amphetamine wikiPageWikiLink Basal_ganglia.
- Amphetamine wikiPageWikiLink Behavioral_addiction.
- Amphetamine wikiPageWikiLink Benzaldehyde.
- Amphetamine wikiPageWikiLink Benzoic_acid.
- Amphetamine wikiPageWikiLink Benzoyl-CoA.
- Amphetamine wikiPageWikiLink Benzphetamine.
- Amphetamine wikiPageWikiLink Benzyl.
- Amphetamine wikiPageWikiLink Benzyl_chloride.
- Amphetamine wikiPageWikiLink Binge_eating_disorder.
- Amphetamine wikiPageWikiLink Bioavailability.
- Amphetamine wikiPageWikiLink Biological_half-life.
- Amphetamine wikiPageWikiLink Biological_target.
- Amphetamine wikiPageWikiLink Bipolar_disorder.
- Amphetamine wikiPageWikiLink Black_market.
- Amphetamine wikiPageWikiLink Blood_plasma.
- Amphetamine wikiPageWikiLink Blood_proteins.
- Amphetamine wikiPageWikiLink Brand.
- Amphetamine wikiPageWikiLink Bruxism.
- Amphetamine wikiPageWikiLink Bupropion.
- Amphetamine wikiPageWikiLink Butyrate—CoA_ligase.
- Amphetamine wikiPageWikiLink CAMK.
- Amphetamine wikiPageWikiLink CREB.
- Amphetamine wikiPageWikiLink CYP2D6.
- Amphetamine wikiPageWikiLink Calcium_channel.
- Amphetamine wikiPageWikiLink Cannabinoid.
- Amphetamine wikiPageWikiLink Cardiovascular_disease.
- Amphetamine wikiPageWikiLink Carnitine.
- Amphetamine wikiPageWikiLink Catecholamine.
- Amphetamine wikiPageWikiLink Category:5-HT1A_agonists.
- Amphetamine wikiPageWikiLink Category:Amphetamine.
- Amphetamine wikiPageWikiLink Category:Anorectics.
- Amphetamine wikiPageWikiLink Category:Aphrodisiacs.
- Amphetamine wikiPageWikiLink Category:Drugs_acting_on_the_cardiovascular_system.
- Amphetamine wikiPageWikiLink Category:Drugs_acting_on_the_nervous_system.
- Amphetamine wikiPageWikiLink Category:Drugs_in_sport.
- Amphetamine wikiPageWikiLink Category:Euphoriants.
- Amphetamine wikiPageWikiLink Category:Excitatory_amino_acid_reuptake_inhibitors.
- Amphetamine wikiPageWikiLink Category:German_inventions.
- Amphetamine wikiPageWikiLink Category:Management_of_obesity.
- Amphetamine wikiPageWikiLink Category:Narcolepsy.
- Amphetamine wikiPageWikiLink Category:Nootropics.
- Amphetamine wikiPageWikiLink Category:Norepinephrine-dopamine_releasing_agents.
- Amphetamine wikiPageWikiLink Category:Phenethylamines.
- Amphetamine wikiPageWikiLink Category:Stimulants.
- Amphetamine wikiPageWikiLink Category:Substituted_amphetamines.
- Amphetamine wikiPageWikiLink Category:TAAR1_agonists.
- Amphetamine wikiPageWikiLink Category:Treatment_and_management_of_attention_deficit_hyperactivity_disorder.
- Amphetamine wikiPageWikiLink Category:VMAT_inhibitors.
- Amphetamine wikiPageWikiLink Cathinone.
- Amphetamine wikiPageWikiLink Caudate_nucleus.
- Amphetamine wikiPageWikiLink Cell_membrane.
- Amphetamine wikiPageWikiLink Central_nervous_system.
- Amphetamine wikiPageWikiLink Chemical_classification.
- Amphetamine wikiPageWikiLink Chemical_synapse.
- Amphetamine wikiPageWikiLink Chiral_ligand.