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- Alpha_sheet abstract "Alpha sheet (also known as alpha pleated sheet or polar pleated sheet) is an atypical secondary structure in proteins, first proposed by Linus Pauling and Robert Corey in 1951. The hydrogen bonding pattern in an alpha sheet is similar to that of a beta sheet, but the orientation of the carbonyl and amino groups in the peptide bond units is distinctive; in a single alpha strand, all of the carbonyl groups are oriented in the same direction on one side of the pleat, and all of the amino groups are oriented in the same direction on the opposite side of the sheet. Thus the alpha sheet accumulates an inherent separation of electrostatic charge, with one edge of the sheet exposing negatively charged carbonyl groups and the opposite edge exposing positively charged amino groups. Unlike the alpha helix and beta sheet, the alpha sheet configuration does not require all component amino acid residues to lie within a single region of dihedral angles; instead, the alpha sheet contains residues of alternating dihedrals in the traditional right-handed (αR) and left-handed (αL) helical regions of Ramachandran space. Although the alpha sheet is only rarely observed in natural protein structures, it has been speculated to play a role in amyloid disease and it was found to be a stable form for amyloidogenic proteins in one set of molecular dynamics simulations. Alpha sheets have also been observed in X-ray crystallography structures of designed peptides.".
- Alpha_sheet thumbnail Alpha_sheet_bonding_schematic-color.svg?width=300.
- Alpha_sheet wikiPageID "9015477".
- Alpha_sheet wikiPageLength "12127".
- Alpha_sheet wikiPageOutDegree "72".
- Alpha_sheet wikiPageRevisionID "681399999".
- Alpha_sheet wikiPageWikiLink Alanine.
- Alpha_sheet wikiPageWikiLink Alpha_helix.
- Alpha_sheet wikiPageWikiLink Alzheimers_disease.
- Alpha_sheet wikiPageWikiLink Amine.
- Alpha_sheet wikiPageWikiLink Amino_acid.
- Alpha_sheet wikiPageWikiLink Amyloid.
- Alpha_sheet wikiPageWikiLink Amyloid_beta.
- Alpha_sheet wikiPageWikiLink Beta-keratin.
- Alpha_sheet wikiPageWikiLink Beta_sheet.
- Alpha_sheet wikiPageWikiLink Biomolecular_structure.
- Alpha_sheet wikiPageWikiLink Carbonyl.
- Alpha_sheet wikiPageWikiLink Category:Protein_structural_motifs.
- Alpha_sheet wikiPageWikiLink Chicken.
- Alpha_sheet wikiPageWikiLink Conformational_change.
- Alpha_sheet wikiPageWikiLink Dextrorotation_and_levorotation.
- Alpha_sheet wikiPageWikiLink Dihedral_angle.
- Alpha_sheet wikiPageWikiLink Dominance_(genetics).
- Alpha_sheet wikiPageWikiLink Electric_charge.
- Alpha_sheet wikiPageWikiLink Electron_crystallography.
- Alpha_sheet wikiPageWikiLink Epimer.
- Alpha_sheet wikiPageWikiLink Fiber_diffraction.
- Alpha_sheet wikiPageWikiLink Glycine.
- Alpha_sheet wikiPageWikiLink Human.
- Alpha_sheet wikiPageWikiLink Huntingtin.
- Alpha_sheet wikiPageWikiLink Huntingtons_disease.
- Alpha_sheet wikiPageWikiLink Hydrogen_bond.
- Alpha_sheet wikiPageWikiLink Isoleucine.
- Alpha_sheet wikiPageWikiLink Linus_Pauling.
- Alpha_sheet wikiPageWikiLink Lysozyme.
- Alpha_sheet wikiPageWikiLink Methyl_group.
- Alpha_sheet wikiPageWikiLink Molecular_dynamics.
- Alpha_sheet wikiPageWikiLink Mutation.
- Alpha_sheet wikiPageWikiLink Native_state.
- Alpha_sheet wikiPageWikiLink Nuclear_magnetic_resonance_spectroscopy_of_proteins.
- Alpha_sheet wikiPageWikiLink Oxygen.
- Alpha_sheet wikiPageWikiLink Peptide.
- Alpha_sheet wikiPageWikiLink Peptide_bond.
- Alpha_sheet wikiPageWikiLink Peptide_plane_flipping.
- Alpha_sheet wikiPageWikiLink Peptide_sequence.
- Alpha_sheet wikiPageWikiLink Phenyl_group.
- Alpha_sheet wikiPageWikiLink Polyglutamine_tract.
- Alpha_sheet wikiPageWikiLink Potassium_channel.
- Alpha_sheet wikiPageWikiLink Prion.
- Alpha_sheet wikiPageWikiLink Protein.
- Alpha_sheet wikiPageWikiLink Protein_family.
- Alpha_sheet wikiPageWikiLink Protein_folding.
- Alpha_sheet wikiPageWikiLink Protein_structure.
- Alpha_sheet wikiPageWikiLink Ramachandran_plot.
- Alpha_sheet wikiPageWikiLink Random_coil.
- Alpha_sheet wikiPageWikiLink Robert_Corey.
- Alpha_sheet wikiPageWikiLink Steric_effects.
- Alpha_sheet wikiPageWikiLink Synaptotagmin_1.
- Alpha_sheet wikiPageWikiLink Tert-Butyloxycarbonyl_protecting_group.
- Alpha_sheet wikiPageWikiLink Transthyretin.
- Alpha_sheet wikiPageWikiLink X-ray_crystallography.
- Alpha_sheet wikiPageWikiLink File:Alpha_sheet_bonding_schematic-color.svg.
- Alpha_sheet wikiPageWikiLink File:Alpha_strand_50_50_vertical.png.
- Alpha_sheet wikiPageWikiLinkText "Alpha sheet".
- Alpha_sheet wikiPageWikiLinkText "alpha sheet".
- Alpha_sheet wikiPageUsesTemplate Template:Clear.
- Alpha_sheet wikiPageUsesTemplate Template:Protein_secondary_structure.
- Alpha_sheet wikiPageUsesTemplate Template:Reflist.
- Alpha_sheet subject Category:Protein_structural_motifs.
- Alpha_sheet hypernym Structure.
- Alpha_sheet type Building.
- Alpha_sheet comment "Alpha sheet (also known as alpha pleated sheet or polar pleated sheet) is an atypical secondary structure in proteins, first proposed by Linus Pauling and Robert Corey in 1951.".
- Alpha_sheet label "Alpha sheet".
- Alpha_sheet sameAs Q3266384.
- Alpha_sheet sameAs Lámina_alfa.
- Alpha_sheet sameAs Αシート.
- Alpha_sheet sameAs m.027th6b.
- Alpha_sheet sameAs Alfa_ravan.
- Alpha_sheet sameAs Alfa_ravan.
- Alpha_sheet sameAs Q3266384.
- Alpha_sheet wasDerivedFrom Alpha_sheet?oldid=681399999.
- Alpha_sheet depiction Alpha_sheet_bonding_schematic-color.svg.
- Alpha_sheet isPrimaryTopicOf Alpha_sheet.