Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Alpha-Melanocyte-stimulating_hormone> ?p ?o }
- Alpha-Melanocyte-stimulating_hormone abstract "Alpha-Melanocyte-stimulating hormone α-Melanocyte-stimulating hormone (α-MSH) is an endogenous peptide hormone and neuropeptide of the melanocortin family, with a tridecapeptide structure and the amino acid sequence Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2. It is the most important of the melanocyte-stimulating hormones (MSHs) (also known as melanotropins) in stimulating melanogenesis, a process that in mammals (including humans) is responsible for pigmentation primarily of the hair and skin. It also plays a role in feeding behavior, energy homeostasis, sexual activity, and protection against ischemia and reperfusion injury.α-MSH is a non-selective full agonist of the melanocortin receptors MC1 (Ki = 0.230 nM), MC3 (Ki = 31.5 nM), MC4 (Ki = 900 nM), and MC5 (Ki = 7160 nM), but not MC2 (which is exclusive for adrenocorticotropic hormone (ACTH)). Activation of the MC1 receptor is responsible for its effect on pigmentation, whereas its regulation of appetite, metabolism, and sexual behavior is mediated through both the MC3 and MC4 receptors.It is generated as a proteolyic cleavage product from ACTH (1-13), which is in turn a cleavage product of proopiomelanocortin (POMC).A few synthetic analogues of α-MSH have been investigated as medicinal drugs due to their photoprotective effects against ultraviolet (UV) radiation from the sun. They include afamelanotide (melanotan) and melanotan II, the former of which being in phase-III clinical trials in the United States. Bremelanotide, another analogue of α-MSH, is currently under development not as a photoprotective agent, but instead for the treatment of sexual dysfunction. All of these drugs have significantly greater potencies than α-MSH, along with improved pharmacokinetics and distinctive selectivity profiles.".
- Alpha-Melanocyte-stimulating_hormone iupacName "N-acetyl-(L)-seryl-(L)-tyrosyl-(L)-seryl-(L)-methionyl-(L)-α-glutamyl-(L)-histidyl-(L)-phenylalanyl-(L)-arginyl-(L)-tryptophylglycyl-(L)-lysyl-(L)-prolyl-(L)-valinamide".
- Alpha-Melanocyte-stimulating_hormone wikiPageID "33862576".
- Alpha-Melanocyte-stimulating_hormone wikiPageLength "6650".
- Alpha-Melanocyte-stimulating_hormone wikiPageOutDegree "52".
- Alpha-Melanocyte-stimulating_hormone wikiPageRevisionID "685992462".
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink ACTH_receptor.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Adrenocorticotropic_hormone.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Afamelanotide.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Agonist.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Beta-Melanocyte-stimulating_hormone.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Binding_selectivity.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Biological_pigment.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Bond_cleavage.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Category:Human_hormones.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Category:Melanocortin_receptor_agonists.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Category:Peptide_hormones.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Chemical_structure.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Clinical_trial.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Drug.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Endogeny_(biology).
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Energy_homeostasis.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Gamma-Melanocyte-stimulating_hormone.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Hair.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Human.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Human_sexual_activity.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Ischemia.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink List_of_feeding_behaviours.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Mammal.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Medicine.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Melanocortin.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Melanocortin_1_receptor.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Melanocortin_3_receptor.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Melanocortin_4_receptor.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Melanocortin_5_receptor.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Melanocortin_receptor.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Melanocyte.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Melanocyte-stimulating_hormone.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Melanotan_II.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Neuropeptide.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Organic_compound.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Peptide.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Peptide_hormone.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Peptide_sequence.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Pharmacokinetics.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Photoprotection.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Potency_(pharmacology).
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Proopiomelanocortin.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Proteolysis.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Reperfusion_injury.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Sexual_dysfunction.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Skin.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Structural_analog.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink Ultraviolet.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLink United_States.
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLinkText "Alpha-Melanocyte-stimulating hormone".
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLinkText "alpha-MSH".
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLinkText "alpha-Melanocyte-stimulating hormone".
- Alpha-Melanocyte-stimulating_hormone wikiPageWikiLinkText "α-MSH".
- Alpha-Melanocyte-stimulating_hormone iupacname "N-acetyl-(L)-seryl-(L)-tyrosyl-(L)-seryl-(L)-methionyl-(L)-α-glutamyl-(L)-histidyl-(L)-phenylalanyl-(L)-arginyl-(L)-tryptophylglycyl-(L)-lysyl-(L)-prolyl-(L)-valinamide".
- Alpha-Melanocyte-stimulating_hormone name "α-Melanocyte-stimulating hormone".
- Alpha-Melanocyte-stimulating_hormone othernames "alpha-MSH, α-melanocortin, α-melanotropin, α-intermedin; Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2".
- Alpha-Melanocyte-stimulating_hormone verifiedfields "changed".
- Alpha-Melanocyte-stimulating_hormone verifiedrevid "477348553".
- Alpha-Melanocyte-stimulating_hormone watchedfields "changed".
- Alpha-Melanocyte-stimulating_hormone wikiPageUsesTemplate Template:Biochemistry-stub.
- Alpha-Melanocyte-stimulating_hormone wikiPageUsesTemplate Template:Cascite.
- Alpha-Melanocyte-stimulating_hormone wikiPageUsesTemplate Template:Chembox.
- Alpha-Melanocyte-stimulating_hormone wikiPageUsesTemplate Template:Chembox_Hazards.
- Alpha-Melanocyte-stimulating_hormone wikiPageUsesTemplate Template:Chembox_Identifiers.
- Alpha-Melanocyte-stimulating_hormone wikiPageUsesTemplate Template:Chembox_Properties.
- Alpha-Melanocyte-stimulating_hormone wikiPageUsesTemplate Template:Chemspidercite.
- Alpha-Melanocyte-stimulating_hormone wikiPageUsesTemplate Template:Ebicite.
- Alpha-Melanocyte-stimulating_hormone wikiPageUsesTemplate Template:Hormones.
- Alpha-Melanocyte-stimulating_hormone wikiPageUsesTemplate Template:Neuropeptidergics.
- Alpha-Melanocyte-stimulating_hormone wikiPageUsesTemplate Template:Neuropeptides.
- Alpha-Melanocyte-stimulating_hormone wikiPageUsesTemplate Template:Reflist.
- Alpha-Melanocyte-stimulating_hormone wikiPageUsesTemplate Template:Stdinchicite.
- Alpha-Melanocyte-stimulating_hormone subject Category:Human_hormones.
- Alpha-Melanocyte-stimulating_hormone subject Category:Melanocortin_receptor_agonists.
- Alpha-Melanocyte-stimulating_hormone subject Category:Peptide_hormones.
- Alpha-Melanocyte-stimulating_hormone hypernym Hormone.
- Alpha-Melanocyte-stimulating_hormone type Agent.
- Alpha-Melanocyte-stimulating_hormone type ChemicalCompound.
- Alpha-Melanocyte-stimulating_hormone type ChemicalSubstance.
- Alpha-Melanocyte-stimulating_hormone type Protein.
- Alpha-Melanocyte-stimulating_hormone type Agent.
- Alpha-Melanocyte-stimulating_hormone type Agonist.
- Alpha-Melanocyte-stimulating_hormone type Chemical.
- Alpha-Melanocyte-stimulating_hormone type Hormone.
- Alpha-Melanocyte-stimulating_hormone type Peptide.
- Alpha-Melanocyte-stimulating_hormone type Redirect.
- Alpha-Melanocyte-stimulating_hormone type ChemicalObject.
- Alpha-Melanocyte-stimulating_hormone type Thing.
- Alpha-Melanocyte-stimulating_hormone type Q11173.
- Alpha-Melanocyte-stimulating_hormone comment "Alpha-Melanocyte-stimulating hormone α-Melanocyte-stimulating hormone (α-MSH) is an endogenous peptide hormone and neuropeptide of the melanocortin family, with a tridecapeptide structure and the amino acid sequence Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2.".
- Alpha-Melanocyte-stimulating_hormone label "Alpha-Melanocyte-stimulating hormone".
- Alpha-Melanocyte-stimulating_hormone sameAs Q4734908.
- Alpha-Melanocyte-stimulating_hormone sameAs آلفا-ملانوسیت-استیمولاتینگ_هورمون.
- Alpha-Melanocyte-stimulating_hormone sameAs m.0hnbqt6.