Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Alfentanil> ?p ?o }
- Alfentanil abstract "Alfentanil (R-39209, trade name Alfenta, Rapifen in Australia) is a potent but short-acting synthetic opioid analgesic drug, used for anaesthesia in surgery. It is an analogue of fentanyl with around 1/4 to 1/10 the potency of fentanyl and around 1/3 of the duration of action, but with an onset of effects 4x faster than fentanyl. Alfentanil has a pKa of approximately 6.5, which leads to a very high proportion of the drug being uncharged at physiologic pH. This unique characteristic is responsible for its rapid onset. It is an agonist at mu opioid receptors.While alfentanil tends to cause fewer cardiovascular complications than other similar drugs such as fentanyl and remifentanil, it tends to give stronger respiratory depression and so requires careful monitoring of breathing and vital signs. Almost exclusively used by anesthesia providers during portions of a case where quick, fast acting (though not long lasting) pain control is needed (i.e. during a nerve block, head pinning etc..) Alfentanil is administered by the parenteral (injected) route for fast onset of effects and precise control of dosage.Alfentanil is a restricted drug which is classified as Schedule II in the USA, according to the U.S. DEA website.Alfentanil was discovered at Janssen Pharmaceutica in 1976.Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.".
- Alfentanil atcPrefix "N01".
- Alfentanil atcSuffix "AH02".
- Alfentanil bioavailability "100.0".
- Alfentanil casNumber "71195-58-9".
- Alfentanil chEBI "2569".
- Alfentanil drugbank "DB00802".
- Alfentanil fdaUniiCode "1N74HM2BS7".
- Alfentanil iupacName "N-{1-[2-(4-ethyl-5-oxo-4,5-dihydro-1H-1,2,3,4-tetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl}-N-phenylpropanamide".
- Alfentanil pubchem "51263".
- Alfentanil thumbnail Alfentanil-2D-skeletal.svg?width=300.
- Alfentanil wikiPageExternalLink a601130.html.
- Alfentanil wikiPageID "1035337".
- Alfentanil wikiPageLength "5382".
- Alfentanil wikiPageOutDegree "32".
- Alfentanil wikiPageRevisionID "685470423".
- Alfentanil wikiPageWikiLink Analgesic.
- Alfentanil wikiPageWikiLink Anesthesia.
- Alfentanil wikiPageWikiLink Category:Anilides.
- Alfentanil wikiPageWikiLink Category:Belgian_inventions.
- Alfentanil wikiPageWikiLink Category:Ethers.
- Alfentanil wikiPageWikiLink Category:General_anesthetics.
- Alfentanil wikiPageWikiLink Category:Janssen_Pharmaceutica.
- Alfentanil wikiPageWikiLink Category:Lactams.
- Alfentanil wikiPageWikiLink Category:Mu-opioid_agonists.
- Alfentanil wikiPageWikiLink Category:Piperidines.
- Alfentanil wikiPageWikiLink Category:Synthetic_opioids.
- Alfentanil wikiPageWikiLink Category:Tetrazoles.
- Alfentanil wikiPageWikiLink Category:Ureas.
- Alfentanil wikiPageWikiLink Circulatory_system.
- Alfentanil wikiPageWikiLink Controlled_Substances_Act.
- Alfentanil wikiPageWikiLink Drug_Enforcement_Administration.
- Alfentanil wikiPageWikiLink Fentanyl.
- Alfentanil wikiPageWikiLink Hypoventilation.
- Alfentanil wikiPageWikiLink Intravenous_therapy.
- Alfentanil wikiPageWikiLink Itch.
- Alfentanil wikiPageWikiLink Janssen_Pharmaceutica.
- Alfentanil wikiPageWikiLink Liver.
- Alfentanil wikiPageWikiLink Nausea.
- Alfentanil wikiPageWikiLink Opioid.
- Alfentanil wikiPageWikiLink Pharmaceutical_drug.
- Alfentanil wikiPageWikiLink Remifentanil.
- Alfentanil wikiPageWikiLink Surgery.
- Alfentanil wikiPageWikiLink Wikt:Parenteral.
- Alfentanil wikiPageWikiLink Μ-opioid_receptor.
- Alfentanil wikiPageWikiLinkText "Alfentanil".
- Alfentanil wikiPageWikiLinkText "Alfentanyl".
- Alfentanil wikiPageWikiLinkText "alfentanil".
- Alfentanil atcPrefix "N01".
- Alfentanil atcSuffix "AH02".
- Alfentanil bioavailability "100.0".
- Alfentanil c "21".
- Alfentanil casNumber "71195".
- Alfentanil chebi "2569".
- Alfentanil chembl "634".
- Alfentanil chemspiderid "46451".
- Alfentanil drugbank "DB00802".
- Alfentanil durationOfAction "900.0".
- Alfentanil eliminationHalfLife "-6660.0".
- Alfentanil h "32".
- Alfentanil inchi "1".
- Alfentanil inchikey "IDBPHNDTYPBSNI-UHFFFAOYAV".
- Alfentanil iupacName "N-{1-[2-ethyl]-4-piperidin-4-yl}-N-phenylpropanamide".
- Alfentanil iupharLigand "7108".
- Alfentanil kegg "D07122".
- Alfentanil legalAu "S8".
- Alfentanil legalDe "Anlage III".
- Alfentanil legalUk "Class A".
- Alfentanil legalUs "Schedule II".
- Alfentanil medlineplus "a601130".
- Alfentanil meltingPoint "140.8".
- Alfentanil metabolism Liver.
- Alfentanil molecularWeight "416.517".
- Alfentanil n "6".
- Alfentanil o "3".
- Alfentanil proteinBound "92.0".
- Alfentanil pubchem "51263".
- Alfentanil routesOfAdministration Intravenous_therapy.
- Alfentanil smiles "O=C1NCCN3CCCCOC".
- Alfentanil stdinchi "1".
- Alfentanil stdinchikey "IDBPHNDTYPBSNI-UHFFFAOYSA-N".
- Alfentanil tradename "Alfenta".
- Alfentanil unii "1".
- Alfentanil verifiedrevid "477317188".
- Alfentanil width "200".
- Alfentanil wikiPageUsesTemplate Template:Analgesics.
- Alfentanil wikiPageUsesTemplate Template:Cascite.
- Alfentanil wikiPageUsesTemplate Template:Chemspidercite.
- Alfentanil wikiPageUsesTemplate Template:Drugbankcite.
- Alfentanil wikiPageUsesTemplate Template:Drugbox.
- Alfentanil wikiPageUsesTemplate Template:Drugs.com.
- Alfentanil wikiPageUsesTemplate Template:Ebicite.
- Alfentanil wikiPageUsesTemplate Template:Fdacite.
- Alfentanil wikiPageUsesTemplate Template:General_anesthetics.
- Alfentanil wikiPageUsesTemplate Template:Keggcite.
- Alfentanil wikiPageUsesTemplate Template:Opioidergics.
- Alfentanil wikiPageUsesTemplate Template:Reflist.
- Alfentanil wikiPageUsesTemplate Template:Stdinchicite.
- Alfentanil subject Category:Anilides.
- Alfentanil subject Category:Belgian_inventions.