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- Alexander_Varshavsky abstract "Alexander Jacob Varshavsky (Russian: Александр Яковлевич Варшавский; born 8 November 1946) is a Russian-American biochemist, noted for his discovery of the N-end rule of ubiquitination. A native of Moscow, he is currently researching at Caltech.Varshavsky provided an original approach to killing cancer cells, proffering the idea of a targeted molecular device that could enter a cell, examine it for DNA deletions specific to cancer and killing it if it meets the right profile. \"(It) involves, in a nutshell, the finding of a genuine Achilles' heel of cancer cells, i.e. their potentially vulnerable feature that won't change during tumor progression,\" said Varshavsky.The approach termed deletion-specific targeting (DST), employs HDs (homozygous DNA deletions) as the targets of cancer therapy. \"In contrast to other attributes of cancer cells, their HDs are immutable markers. If the DST strategy can be implemented in a clinical setting, it may prove to be both curative and free of side effects.\"".
- Alexander_Varshavsky wikiPageExternalLink Varshavsky.
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- Alexander_Varshavsky wikiPageWikiLink Albany_Medical_Center_Prize.
- Alexander_Varshavsky wikiPageWikiLink Albert_Lasker_Award_for_Basic_Medical_Research.
- Alexander_Varshavsky wikiPageWikiLink BBVA_Foundation_Frontiers_of_Knowledge_Award.
- Alexander_Varshavsky wikiPageWikiLink Breakthrough_Prize_in_Life_Sciences.
- Alexander_Varshavsky wikiPageWikiLink California_Institute_of_Technology.
- Alexander_Varshavsky wikiPageWikiLink Category:1946_births.
- Alexander_Varshavsky wikiPageWikiLink Category:American_biochemists.
- Alexander_Varshavsky wikiPageWikiLink Category:American_medical_researchers.
- Alexander_Varshavsky wikiPageWikiLink Category:American_people_of_Russian_descent.
- Alexander_Varshavsky wikiPageWikiLink Category:Living_people.
- Alexander_Varshavsky wikiPageWikiLink Category:Massry_Prize_recipients.
- Alexander_Varshavsky wikiPageWikiLink Category:Members_of_the_United_States_National_Academy_of_Sciences.
- Alexander_Varshavsky wikiPageWikiLink Category:Recipients_of_the_Albert_Lasker_Award_for_Basic_Medical_Research.
- Alexander_Varshavsky wikiPageWikiLink Category:Wolf_Prize_in_Medicine_laureates.
- Alexander_Varshavsky wikiPageWikiLink Columbia_University.
- Alexander_Varshavsky wikiPageWikiLink Competitions_and_prizes_in_biotechnology.
- Alexander_Varshavsky wikiPageWikiLink Gairdner_Foundation_International_Award.
- Alexander_Varshavsky wikiPageWikiLink Keck_School_of_Medicine_of_USC.
- Alexander_Varshavsky wikiPageWikiLink King_Faisal_International_Prize.
- Alexander_Varshavsky wikiPageWikiLink Louisa_Gross_Horwitz_Prize.
- Alexander_Varshavsky wikiPageWikiLink March_of_Dimes_Prize_in_Developmental_Biology.
- Alexander_Varshavsky wikiPageWikiLink Massry_Prize.
- Alexander_Varshavsky wikiPageWikiLink N-end_rule.
- Alexander_Varshavsky wikiPageWikiLink Otto_Warburg_Medal.
- Alexander_Varshavsky wikiPageWikiLink The_Vilcek_Foundation.
- Alexander_Varshavsky wikiPageWikiLink Ubiquitin.
- Alexander_Varshavsky wikiPageWikiLink University_of_Southern_California.
- Alexander_Varshavsky wikiPageWikiLink Wolf_Prize_in_Medicine.
- Alexander_Varshavsky wikiPageWikiLinkText "Alexander Jacob Varshavsky".
- Alexander_Varshavsky wikiPageWikiLinkText "Alexander Varshavsky".
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- Alexander_Varshavsky wikiPageUsesTemplate Template:Lang-ru.
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- Alexander_Varshavsky wikiPageUsesTemplate Template:US-biochemist-stub.
- Alexander_Varshavsky wikiPageUsesTemplate Template:Wolf_Prize_in_Medicine.
- Alexander_Varshavsky subject Category:1946_births.
- Alexander_Varshavsky subject Category:American_biochemists.
- Alexander_Varshavsky subject Category:American_medical_researchers.
- Alexander_Varshavsky subject Category:American_people_of_Russian_descent.
- Alexander_Varshavsky subject Category:Living_people.
- Alexander_Varshavsky subject Category:Massry_Prize_recipients.
- Alexander_Varshavsky subject Category:Members_of_the_United_States_National_Academy_of_Sciences.
- Alexander_Varshavsky subject Category:Recipients_of_the_Albert_Lasker_Award_for_Basic_Medical_Research.
- Alexander_Varshavsky subject Category:Wolf_Prize_in_Medicine_laureates.
- Alexander_Varshavsky hypernym Biochemist.
- Alexander_Varshavsky type Award.
- Alexander_Varshavsky type Biologist.
- Alexander_Varshavsky type List.
- Alexander_Varshavsky type Person.
- Alexander_Varshavsky type Scientist.
- Alexander_Varshavsky type Award.
- Alexander_Varshavsky type Biologist.
- Alexander_Varshavsky type Laureate.
- Alexander_Varshavsky type List.
- Alexander_Varshavsky type Member.
- Alexander_Varshavsky type Scientist.
- Alexander_Varshavsky type Winner.
- Alexander_Varshavsky type Thing.
- Alexander_Varshavsky comment "Alexander Jacob Varshavsky (Russian: Александр Яковлевич Варшавский; born 8 November 1946) is a Russian-American biochemist, noted for his discovery of the N-end rule of ubiquitination. A native of Moscow, he is currently researching at Caltech.Varshavsky provided an original approach to killing cancer cells, proffering the idea of a targeted molecular device that could enter a cell, examine it for DNA deletions specific to cancer and killing it if it meets the right profile.".
- Alexander_Varshavsky label "Alexander Varshavsky".
- Alexander_Varshavsky sameAs Q442466.
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- Alexander_Varshavsky sameAs Варшавский,_Александр_Яковлевич.
- Alexander_Varshavsky sameAs Alexander_Varshavsky.
- Alexander_Varshavsky sameAs Q442466.
- Alexander_Varshavsky sameAs 亚历山大·瓦尔沙夫斯基.
- Alexander_Varshavsky wasDerivedFrom Alexander_Varshavsky?oldid=707746650.
- Alexander_Varshavsky isPrimaryTopicOf Alexander_Varshavsky.