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- Aldophosphamide abstract "Aldophosphamide is a tautomer of the main active metabolite of the alkylating antineoplastic agent cyclophosphamide - the 4-hydroxycyclophosphamide. Some of the aldophosphamide is then intracellularly hydrolyzed by the enzyme phosphatase to the of the two directly cytotoxically active metabolites - phosphoramide mustard and acrolein - in the metabolic activation pathway of the cyclophosphamide. But most of the aldophosphamide undergoes metabolic inactivation, catalyzed by another enzyme, ALDH, which gives rise to carboxycyclophosphamide.Aldophosphamide residue is a component in molecules of some new oxazaphosphorine anticancer drugs that are now underway in clinical and preclinical testing: the NSC 612567 (aldophosphamide perhydrothiazine) and NSC 613060 (aldophosphamide thiazolidine).".
- Aldophosphamide wikiPageID "41859566".
- Aldophosphamide wikiPageLength "1411".
- Aldophosphamide wikiPageOutDegree "20".
- Aldophosphamide wikiPageRevisionID "621059831".
- Aldophosphamide wikiPageWikiLink 4-Hydroxycyclophosphamide.
- Aldophosphamide wikiPageWikiLink Acrolein.
- Aldophosphamide wikiPageWikiLink Aldehyde_dehydrogenase.
- Aldophosphamide wikiPageWikiLink Alkylating_antineoplastic_agent.
- Aldophosphamide wikiPageWikiLink Carboxycyclophosphamide.
- Aldophosphamide wikiPageWikiLink Catalysis.
- Aldophosphamide wikiPageWikiLink Category:IARC_Group_1_carcinogens.
- Aldophosphamide wikiPageWikiLink Category:Nitrogen_mustards.
- Aldophosphamide wikiPageWikiLink Category:Organochlorides.
- Aldophosphamide wikiPageWikiLink Category:Oxazaphosphinans.
- Aldophosphamide wikiPageWikiLink Category:Phosphorodiamidates.
- Aldophosphamide wikiPageWikiLink Category:Prodrugs.
- Aldophosphamide wikiPageWikiLink Cyclophosphamide.
- Aldophosphamide wikiPageWikiLink Cytotoxicity.
- Aldophosphamide wikiPageWikiLink Enzyme.
- Aldophosphamide wikiPageWikiLink Hydrolysis.
- Aldophosphamide wikiPageWikiLink Phosphatase.
- Aldophosphamide wikiPageWikiLink Phosphoramide_mustard.
- Aldophosphamide wikiPageWikiLink Tautomer.
- Aldophosphamide wikiPageWikiLinkText "aldophosphamide".
- Aldophosphamide wikiPageUsesTemplate Template:Antineoplastic-drug-stub.
- Aldophosphamide wikiPageUsesTemplate Template:Chemotherapeutic_agents.
- Aldophosphamide wikiPageUsesTemplate Template:Confusing.
- Aldophosphamide wikiPageUsesTemplate Template:Multiple_issues.
- Aldophosphamide wikiPageUsesTemplate Template:One_source.
- Aldophosphamide wikiPageUsesTemplate Template:Reflist.
- Aldophosphamide wikiPageUsesTemplate Template:Technical.
- Aldophosphamide subject Category:IARC_Group_1_carcinogens.
- Aldophosphamide subject Category:Nitrogen_mustards.
- Aldophosphamide subject Category:Organochlorides.
- Aldophosphamide subject Category:Oxazaphosphinans.
- Aldophosphamide subject Category:Phosphorodiamidates.
- Aldophosphamide subject Category:Prodrugs.
- Aldophosphamide hypernym Tautomer.
- Aldophosphamide comment "Aldophosphamide is a tautomer of the main active metabolite of the alkylating antineoplastic agent cyclophosphamide - the 4-hydroxycyclophosphamide. Some of the aldophosphamide is then intracellularly hydrolyzed by the enzyme phosphatase to the of the two directly cytotoxically active metabolites - phosphoramide mustard and acrolein - in the metabolic activation pathway of the cyclophosphamide.".
- Aldophosphamide label "Aldophosphamide".
- Aldophosphamide sameAs Q15711205.
- Aldophosphamide sameAs m.0_l9csp.
- Aldophosphamide sameAs Алдофосфамид.
- Aldophosphamide sameAs Q15711205.
- Aldophosphamide wasDerivedFrom Aldophosphamide?oldid=621059831.
- Aldophosphamide isPrimaryTopicOf Aldophosphamide.