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- b_hammerhead_domain abstract "The aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain is an evolutionary conserved protein domain.Aldehyde oxidase (EC 1.2.3.1) catalyzes the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase (EC 1.1.1.204) catalyzes the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase (EC 1.1.3.22) activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulfhydryl groups.".
- b_hammerhead_domain symbol "Ald_Xan_dh_C".
- b_hammerhead_domain wikiPageID "29406902".
- b_hammerhead_domain wikiPageLength "2672".
- b_hammerhead_domain wikiPageOutDegree "12".
- b_hammerhead_domain wikiPageRevisionID "590524099".
- b_hammerhead_domain wikiPageWikiLink Aldehyde.
- b_hammerhead_domain wikiPageWikiLink Aldehyde_oxidase.
- b_hammerhead_domain wikiPageWikiLink Aldehyde_oxidase_1.
- b_hammerhead_domain wikiPageWikiLink Category:Protein_domains.
- b_hammerhead_domain wikiPageWikiLink Flavin_adenine_dinucleotide.
- b_hammerhead_domain wikiPageWikiLink Molybdenum.
- b_hammerhead_domain wikiPageWikiLink Protein_domain.
- b_hammerhead_domain wikiPageWikiLink Thiol.
- b_hammerhead_domain wikiPageWikiLink Uric_acid.
- b_hammerhead_domain wikiPageWikiLink Xanthine.
- b_hammerhead_domain wikiPageWikiLink Xanthine_dehydrogenase.
- b_hammerhead_domain wikiPageWikiLinkText "Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain".
- b_hammerhead_domain wikiPageWikiLinkText "aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain".
- b_hammerhead_domain interpro "IPR000674".
- b_hammerhead_domain name "Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain".
- b_hammerhead_domain pdb "E:28-142 E:35-144 B:35-144 B:35-144 E:35-144 E:35-144 E:35-144 D:25-131 A:25-131 A:587-693 B:587-693 A:587-693 B:587-693 B:587-693 C:587-693 A:203-308 A:192-308 A:192-308".
- b_hammerhead_domain pfam "PF01315".
- b_hammerhead_domain scop "1".
- b_hammerhead_domain symbol "Ald_Xan_dh_C".
- b_hammerhead_domain wikiPageUsesTemplate Template:Cite_journal.
- b_hammerhead_domain wikiPageUsesTemplate Template:EC_number.
- b_hammerhead_domain wikiPageUsesTemplate Template:InterPro_content.
- b_hammerhead_domain wikiPageUsesTemplate Template:PDB3.
- b_hammerhead_domain wikiPageUsesTemplate Template:Pfam_box.
- b_hammerhead_domain wikiPageUsesTemplate Template:Protein-stub.
- b_hammerhead_domain wikiPageUsesTemplate Template:Refbegin.
- b_hammerhead_domain wikiPageUsesTemplate Template:Refend.
- b_hammerhead_domain subject Category:Protein_domains.
- b_hammerhead_domain hypernym Catalyzes.
- b_hammerhead_domain type Biomolecule.
- b_hammerhead_domain type Protein.
- b_hammerhead_domain type Domain.
- b_hammerhead_domain type Thing.
- b_hammerhead_domain type Q206229.
- b_hammerhead_domain type Q8054.
- b_hammerhead_domain comment "The aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain is an evolutionary conserved protein domain.Aldehyde oxidase (EC 1.2.3.1) catalyzes the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors.".
- b_hammerhead_domain label "Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain".
- b_hammerhead_domain sameAs Q4713510.
- b_hammerhead_domain sameAs m.0dscjlf.
- b_hammerhead_domain sameAs Q4713510.
- b_hammerhead_domain wasDerivedFrom b_hammerhead_domain?oldid=590524099.
- b_hammerhead_domain isPrimaryTopicOf b_hammerhead_domain.