Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Acitretin> ?p ?o }
- Acitretin abstract "Acitretin (trade names Soriatane and Neotigason) is a second-generation retinoid. It is taken orally, and is typically used for psoriasis.It is a metabolite of etretinate, which was used prior to the introduction of acitretin. Etretinate was discontinued because it had a narrow therapeutic index as well as a long elimination half-life (t1/2=120 days), making dosing difficult. In contrast, acitretin's half-life is approximately 2 days. However, because acitretin can be reverse metabolised into etretinate which has an extremely long half-life, women must avoid becoming pregnant for at least 3 years after discontinuing acitretin. Therefore, acitretin is generally not recommended for women of child-bearing age with a risk of becoming pregnant.Acitretin is an oral retinoid used in the treatment of severe resistant psoriasis. Because of the potential for problems and severe side effects it is generally used in only very severe cases of psoriasis that have been unresponsive to other treatments. It binds to nuclear receptors that regulates gene transcription. They induce keratinocyte differentiation and reduce epidermal hyperplasia, leading to the slowing of cell reproduction. Acitretin is readily absorbed and widely distributed after oral administration. A therapeutic effect occurs after 2 to 4 weeks or longer.Patients that have received the medication are advised against giving blood for at least 3 years due to the risk of birth defects.".
- Acitretin atcPrefix "D05".
- Acitretin atcSuffix "BB02".
- Acitretin bioavailability "60.0".
- Acitretin casNumber "55079-83-9".
- Acitretin chEBI "50173".
- Acitretin drugbank "DB00459".
- Acitretin fdaUniiCode "LCH760E9T7".
- Acitretin iupacName "(2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid".
- Acitretin pubchem "5284513".
- Acitretin thumbnail Acitretin2DACS.svg?width=300.
- Acitretin wikiPageID "1300834".
- Acitretin wikiPageLength "4988".
- Acitretin wikiPageOutDegree "9".
- Acitretin wikiPageRevisionID "688426272".
- Acitretin wikiPageWikiLink Biological_half-life.
- Acitretin wikiPageWikiLink Category:Phenol_ethers.
- Acitretin wikiPageWikiLink Category:Retinoids.
- Acitretin wikiPageWikiLink Etretinate.
- Acitretin wikiPageWikiLink Keratinocyte.
- Acitretin wikiPageWikiLink Psoriasis.
- Acitretin wikiPageWikiLink Retinoid.
- Acitretin wikiPageWikiLink Therapeutic_index.
- Acitretin wikiPageWikiLinkText "Acitretin".
- Acitretin wikiPageWikiLinkText "acitretin".
- Acitretin atcPrefix "D05".
- Acitretin atcSuffix "BB02".
- Acitretin bioavailability "60.0".
- Acitretin c "21".
- Acitretin casNumber "55079".
- Acitretin chebi "50173".
- Acitretin chembl "1131".
- Acitretin chemspiderid "4447573".
- Acitretin drugbank "DB00459".
- Acitretin eliminationHalfLife "176400.0".
- Acitretin excretion "Faeces & urine".
- Acitretin h "26".
- Acitretin inchi "1".
- Acitretin inchikey "IHUNBGSDBOWDMA-AQFIFDHZBN".
- Acitretin iupacName "-9".
- Acitretin iupharLigand "7598".
- Acitretin kegg "D02754".
- Acitretin legalAu "S4".
- Acitretin legalCa "Rx-only".
- Acitretin legalUk "POM".
- Acitretin legalUs "Rx-only".
- Acitretin medlineplus "a601010".
- Acitretin metabolism "Hepatic".
- Acitretin molecularWeight "326.429".
- Acitretin o "3".
- Acitretin pregnancyAu "X".
- Acitretin pregnancyUs "X".
- Acitretin pubchem "5284513".
- Acitretin routesOfAdministration "Oral".
- Acitretin smiles "O=C\C=CC".
- Acitretin stdinchi "1".
- Acitretin stdinchikey "IHUNBGSDBOWDMA-AQFIFDHZSA-N".
- Acitretin tradename "Soriatane, Neotigason".
- Acitretin unii "LCH760E9T7".
- Acitretin verifiedrevid "477240755".
- Acitretin wikiPageUsesTemplate Template:Antipsoriatics.
- Acitretin wikiPageUsesTemplate Template:Cascite.
- Acitretin wikiPageUsesTemplate Template:Chemspidercite.
- Acitretin wikiPageUsesTemplate Template:Drugbankcite.
- Acitretin wikiPageUsesTemplate Template:Drugbox.
- Acitretin wikiPageUsesTemplate Template:Drugs.com.
- Acitretin wikiPageUsesTemplate Template:Ebicite.
- Acitretin wikiPageUsesTemplate Template:Fdacite.
- Acitretin wikiPageUsesTemplate Template:Keggcite.
- Acitretin wikiPageUsesTemplate Template:Nuclear_receptor_ligands.
- Acitretin wikiPageUsesTemplate Template:Reflist.
- Acitretin wikiPageUsesTemplate Template:Stdinchicite.
- Acitretin subject Category:Phenol_ethers.
- Acitretin subject Category:Retinoids.
- Acitretin hypernym Retinoid.
- Acitretin type ChemicalSubstance.
- Acitretin type Drug.
- Acitretin type Drug.
- Acitretin type Ether.
- Acitretin type Redirect.
- Acitretin type Teratogen.
- Acitretin type Terpene.
- Acitretin type ChemicalObject.
- Acitretin type Thing.
- Acitretin type Q8386.
- Acitretin comment "Acitretin (trade names Soriatane and Neotigason) is a second-generation retinoid. It is taken orally, and is typically used for psoriasis.It is a metabolite of etretinate, which was used prior to the introduction of acitretin. Etretinate was discontinued because it had a narrow therapeutic index as well as a long elimination half-life (t1/2=120 days), making dosing difficult. In contrast, acitretin's half-life is approximately 2 days.".
- Acitretin label "Acitretin".
- Acitretin sameAs Q341500.
- Acitretin sameAs أسيتريتين.
- Acitretin sameAs Acitretin.
- Acitretin sameAs اسیترتین.
- Acitretin sameAs Acitrétine.
- Acitretin sameAs Acitretin.
- Acitretin sameAs Acitretina.
- Acitretin sameAs 아시트레틴.
- Acitretin sameAs Acitretine.
- Acitretin sameAs Acytretyna.
- Acitretin sameAs Acitretina.
- Acitretin sameAs m.04r3nh.
- Acitretin sameAs Acitretin.