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- Abstral abstract "Abstral is a formulation of fentanyl citrate available as a sublingual tablet. It dissolves quickly and is absorbed through the sublingual mucosa to provide rapid analgesia. In the UK, Abstral is licensed for the treatment of breakthrough cancer pain (BTcP) in patients with otherwise stable, baseline persistent pain that is managed with conventional opioids.The active constituent of Abstral is fentanyl, which is classified as a controlled Class A drug under the Misuse of Drugs Act 1971 in the UK.When used under license, fentanyl is a highly lipophilic compound, which is well absorbed sublingually and generally well tolerated. Other pharmaceutical preparations licensed for breakthrough cancer pain in the UK, which contain fentanyl are: Actiq, Effentora, Instanyl and PecFent. Abstral is manufactured and marketed by Sentynl Therapeutics, Inc..Currently, patients receive conventional oral opioids (e.g. morphine) to treat their breakthrough cancer pain episodes. However, the pharmacokinetic profile of conventional opioids does not fit the profile of breakthrough cancer pain. A breakthrough cancer pain episode is rapid in onset, short in duration and severe in intensity, while an opioid such as morphine is slow in onset and long in duration. This necessitated the development of specialised, fast-acting fentanyl preparations.".
- Abstral wikiPageExternalLink fentanyl.
- Abstral wikiPageExternalLink cannotaccess?ac=0&a=1364d&t=article&n=11286&p=tml&title=In%20Brief:%20Fentanyl%20Sublingual%20Tablets%20(Abstral)%20for%20Breakthrough%20Cancer%20Pain&i=1364.
- Abstral wikiPageExternalLink fda-approval-abstral-fentanyl-sublingual-2490.html.
- Abstral wikiPageExternalLink ?query=abstral&rank=24.
- Abstral wikiPageExternalLink Appraisal%20report%20novel-fentanyl-analgesics.pdf.
- Abstral wikiPageID "32186072".
- Abstral wikiPageLength "6125".
- Abstral wikiPageOutDegree "15".
- Abstral wikiPageRevisionID "705343593".
- Abstral wikiPageWikiLink Actiq.
- Abstral wikiPageWikiLink Analgesic.
- Abstral wikiPageWikiLink Cancer_pain.
- Abstral wikiPageWikiLink Category:Analgesics.
- Abstral wikiPageWikiLink Fentanyl.
- Abstral wikiPageWikiLink Misuse_of_Drugs_Act_1971.
- Abstral wikiPageWikiLink Morphine.
- Abstral wikiPageWikiLink Opioid.
- Abstral wikiPageWikiLink PecFent.
- Abstral wikiPageWikiLink Sentynl_Therapeutics,_Inc..
- Abstral wikiPageWikiLink Specialty_drugs_(United_States).
- Abstral wikiPageWikiLink Sublingual_administration.
- Abstral wikiPageWikiLinkText "Abstral".
- Abstral wikiPageUsesTemplate Template:Merge_to.
- Abstral wikiPageUsesTemplate Template:Reflist.
- Abstral subject Category:Analgesics.
- Abstral hypernym Formulation.
- Abstral type Drug.
- Abstral type Analgesic.
- Abstral type Drug.
- Abstral comment "Abstral is a formulation of fentanyl citrate available as a sublingual tablet. It dissolves quickly and is absorbed through the sublingual mucosa to provide rapid analgesia.".
- Abstral label "Abstral".
- Abstral sameAs Q4669977.
- Abstral sameAs m.0h1bjxm.
- Abstral sameAs Q4669977.
- Abstral wasDerivedFrom Abstral?oldid=705343593.
- Abstral isPrimaryTopicOf Abstral.